SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ctf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 3ctf GLUTAREDOXIN-2
(Saccharomyces
cerevisiae) 		5 / 12 SER A 104
TYR A 113
ALA A  56
GLY A  93
LEU A  87
 None
 1.22A 4j7xB-3ctfA:
undetectable		 4j7xB-3ctfA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA610_0
(SERUM ALBUMIN)		 3ctf GLUTAREDOXIN-2
(Saccharomyces
cerevisiae) 		3 / 3 VAL A  36
SER A  37
THR A  40
 None
 0.32A 4luhA-3ctfA:
undetectable		 4luhA-3ctfA:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3ctf GLUTAREDOXIN-2
(Saccharomyces
cerevisiae) 		3 / 3 ILE A 119
VAL A 112
PRO A 110
 None
 0.69A 5uunA-3ctfA:
5.7		 5uunA-3ctfA:
18.47