SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ctm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3ctm CARBONYL REDUCTASE
(Candida
parapsilosis) 		4 / 7 TYR A  54
THR A 265
SER A 166
VAL A 116
 None
 1.12A 1tv8A-3ctmA:
2.4		 1tv8A-3ctmA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 3ctm CARBONYL REDUCTASE
(Candida
parapsilosis) 		4 / 6 LEU A 167
ALA A 117
SER A  38
THR A  40
 None
 1.07A 1tyrA-3ctmA:
undetectable		 1tyrA-3ctmA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3ctm CARBONYL REDUCTASE
(Candida
parapsilosis) 		5 / 11 TYR A 254
ILE A  46
VAL A  50
ALA A  51
ILE A  63
 None
 1.01A 1uduA-3ctmA:
undetectable		 1uduA-3ctmA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 3ctm CARBONYL REDUCTASE
(Candida
parapsilosis) 		3 / 3 TRP A  48
THR A  80
TYR A  81
 None
 0.96A 2a3aA-3ctmA:
3.8		 2a3aA-3ctmA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 3ctm CARBONYL REDUCTASE
(Candida
parapsilosis) 		3 / 3 TRP A  48
THR A  80
TYR A  81
 None
 1.04A 2a3aB-3ctmA:
3.9		 2a3aB-3ctmA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 3ctm CARBONYL REDUCTASE
(Candida
parapsilosis) 		3 / 3 TRP A  48
THR A  80
TYR A  81
 None
 0.98A 2a3bA-3ctmA:
3.6		 2a3bA-3ctmA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3ctm CARBONYL REDUCTASE
(Candida
parapsilosis) 		4 / 8 TYR A  54
THR A 265
SER A 166
VAL A 116
 None
 1.14A 2fb2A-3ctmA:
2.1		 2fb2A-3ctmA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3ctm CARBONYL REDUCTASE
(Candida
parapsilosis) 		4 / 7 TYR A  54
THR A 265
SER A 166
VAL A 116
 None
 1.14A 2fb2B-3ctmA:
3.1		 2fb2B-3ctmA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3ctm CARBONYL REDUCTASE
(Candida
parapsilosis) 		4 / 5 SER A 166
SER A 259
VAL A 114
SER A 262
 None
 1.24A 2j9cA-3ctmA:
undetectable
2j9cB-3ctmA:
undetectable
2j9cC-3ctmA:
undetectable		 2j9cA-3ctmA:
17.73
2j9cB-3ctmA:
17.73
2j9cC-3ctmA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3ctm CARBONYL REDUCTASE
(Candida
parapsilosis) 		4 / 7 SER A 166
SER A 259
VAL A 114
SER A 262
 None
 1.24A 2j9cA-3ctmA:
undetectable
2j9cB-3ctmA:
undetectable
2j9cC-3ctmA:
undetectable		 2j9cA-3ctmA:
17.73
2j9cB-3ctmA:
17.73
2j9cC-3ctmA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_A_SALA257_1
(TRANSCRIPTIONAL
REGULATOR)		 3ctm CARBONYL REDUCTASE
(Candida
parapsilosis) 		4 / 8 SER A  42
ALA A  62
THR A 101
ILE A 102
 None
 0.77A 3bpxA-3ctmA:
undetectable
3bpxB-3ctmA:
undetectable		 3bpxA-3ctmA:
16.96
3bpxB-3ctmA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA2_1
(CYTOCHROME P450 2D6)		 3ctm CARBONYL REDUCTASE
(Candida
parapsilosis) 		5 / 11 THR A 124
THR A 101
VAL A  98
SER A  43
VAL A 116
 None
 1.43A 3tbgA-3ctmA:
undetectable		 3tbgA-3ctmA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3ctm CARBONYL REDUCTASE
(Candida
parapsilosis) 		5 / 12 GLY A  58
ALA A  55
THR A  80
ALA A  37
VAL A  61
 None
 0.99A 4df3B-3ctmA:
7.3		 4df3B-3ctmA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE0_A_40LA1101_0
(PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM)		 3ctm CARBONYL REDUCTASE
(Candida
parapsilosis) 		5 / 12 ILE A 272
TYR A 254
VAL A 251
THR A 221
ILE A  46
 None
 1.44A 4xe0A-3ctmA:
undetectable		 4xe0A-3ctmA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)		 3ctm CARBONYL REDUCTASE
(Candida
parapsilosis) 		5 / 12 ASP A 222
ALA A  49
GLY A  41
GLY A  44
VAL A  39
 None
 1.30A 6clxA-3ctmA:
6.0		 6clxA-3ctmA:
20.42