SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ctt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		3 / 3 LEU A 151
SER A 230
ASN A 176
 None
 0.73A 1bx4A-3cttA:
undetectable		 1bx4A-3cttA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 9 LEU A 558
LEU A 562
ILE A 565
HIS A 538
LEU A 540
 None
 1.49A 1ereA-3cttA:
undetectable		 1ereA-3cttA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 9 LEU A 558
LEU A 562
ILE A 565
HIS A 538
LEU A 540
 None
 1.48A 1ereB-3cttA:
undetectable		 1ereB-3cttA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 9 LEU A 558
LEU A 562
ILE A 565
HIS A 538
LEU A 540
 None
 1.49A 1ereC-3cttA:
undetectable		 1ereC-3cttA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 9 LEU A 558
LEU A 562
ILE A 565
HIS A 538
LEU A 540
 None
 1.47A 1ereD-3cttA:
undetectable		 1ereD-3cttA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 THR A 416
TYR A 415
ILE A 442
ILE A 523
ALA A 216
 None
None
None
GOL  A3002 (-4.7A)
None
 1.14A 1jtxA-3cttA:
undetectable		 1jtxA-3cttA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1867_0
(FPRA)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 4 ALA A 250
ARG A 171
GLN A 246
GLU A  11
 None
 1.36A 1lqtB-3cttA:
undetectable		 1lqtB-3cttA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1424_0
(FPRA)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 4 ALA A 250
ARG A 171
GLN A 246
GLU A  11
 None
 1.38A 1lquB-3cttA:
undetectable		 1lquB-3cttA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 6 ASP A 396
GLY A 397
THR A 399
PRO A 400
 None
NAG  A2002 (-4.7A)
None
None
 0.88A 1n4fA-3cttA:
undetectable		 1n4fA-3cttA:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 7 TYR A 733
GLU A 760
PHE A 659
ALA A 698
 None
 1.13A 1oniD-3cttA:
undetectable
1oniE-3cttA:
undetectable		 1oniD-3cttA:
10.62
1oniE-3cttA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_F_BEZF511_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 5 GLU A 760
PHE A 659
ARG A 730
ALA A 698
 None
 1.44A 1oniE-3cttA:
0.0
1oniF-3cttA:
0.0		 1oniE-3cttA:
10.62
1oniF-3cttA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_F_BEZF511_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 5 TYR A 733
GLU A 760
PHE A 659
ALA A 698
 None
 1.03A 1oniE-3cttA:
0.0
1oniF-3cttA:
0.0		 1oniE-3cttA:
10.62
1oniF-3cttA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA501_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 9 GLY A 614
ALA A 611
SER A 617
LEU A 620
LEU A 319
 None
 1.27A 1y7iA-3cttA:
undetectable		 1y7iA-3cttA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 7 LEU A 499
GLY A 501
THR A 525
ILE A 565
 None
 0.80A 2bdmA-3cttA:
undetectable		 2bdmA-3cttA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 8 SER A 597
TRP A 674
ALA A 652
LEU A 558
 None
 0.87A 2bxkA-3cttA:
undetectable		 2bxkA-3cttA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2001_1
(SERUM ALBUMIN)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 8 SER A 597
TRP A 674
ALA A 652
LEU A 558
 None
 0.85A 2bxmA-3cttA:
undetectable		 2bxmA-3cttA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 7 ARG A 144
LEU A 151
PHE A 152
LEU A 266
 None
 1.07A 2eimC-3cttA:
undetectable
2eimJ-3cttA:
undetectable		 2eimC-3cttA:
14.24
2eimJ-3cttA:
5.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 11 GLY A 556
ASP A 542
ASN A 543
GLY A 569
PHE A 575
 None
3CU  A1001 ( 2.5A)
None
None
3CU  A1001 (-4.5A)
 1.21A 2hmaA-3cttA:
undetectable		 2hmaA-3cttA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		3 / 3 ASN A 561
LEU A 562
HIS A 657
 None
 0.82A 2q6fB-3cttA:
undetectable		 2q6fB-3cttA:
17.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		8 / 12 ASP A 203
ASN A 207
ASP A 327
ILE A 328
ASP A 542
PHE A 575
ALA A 576
HIS A 600
 GOL  A3001 (-2.6A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-3.9A)
 1.44A 2qmjA-3cttA:
61.8		 2qmjA-3cttA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		12 / 12 ASP A 203
ASN A 207
ASP A 327
ILE A 328
ILE A 364
TRP A 406
ASP A 443
ARG A 526
ASP A 542
PHE A 575
ALA A 576
HIS A 600
 GOL  A3001 (-2.6A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-3.9A)
 0.33A 2qmjA-3cttA:
61.8		 2qmjA-3cttA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ASP A 327
ILE A 364
ASP A 571
PHE A 575
ALA A 576
 3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 4.8A)
3CU  A1001 (-4.5A)
None
 1.38A 2qmjA-3cttA:
61.8		 2qmjA-3cttA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ASP A 542
ASP A 366
ILE A 364
ILE A 328
ASP A 203
 3CU  A1001 ( 2.5A)
None
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
GOL  A3001 (-2.6A)
 1.17A 2qmjA-3cttA:
61.8		 2qmjA-3cttA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ILE A 364
ARG A 598
ASP A 571
PHE A 575
ALA A 576
 3CU  A1001 (-4.5A)
3CU  A1001 ( 4.7A)
3CU  A1001 ( 4.8A)
3CU  A1001 (-4.5A)
None
 1.43A 2qmjA-3cttA:
61.8		 2qmjA-3cttA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMJ_A_ACRA1001_2
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 6 THR A 205
TYR A 299
TRP A 441
MET A 444
TRP A 539
THR A 544
 None
3CU  A1001 (-3.6A)
3CU  A1001 (-4.9A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.6A)
None
 0.26A 2qmjA-3cttA:
61.8		 2qmjA-3cttA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ASP A 203
ASP A 327
ASP A 443
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.51A 2x2iA-3cttA:
36.2		 2x2iA-3cttA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1050_2
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 6 TRP A 441
MET A 444
ARG A 526
TRP A 539
 3CU  A1001 (-4.9A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
 0.52A 2x2iA-3cttA:
36.1		 2x2iA-3cttA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 203
ASP A 327
ASP A 443
MET A 444
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.60A 2x2iB-3cttA:
32.4		 2x2iB-3cttA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 203
ASP A 327
ASP A 443
MET A 444
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.52A 2x2iC-3cttA:
36.2		 2x2iC-3cttA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_D_QPSD1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 203
ASP A 327
ASP A 443
MET A 444
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.52A 2x2iD-3cttA:
32.3		 2x2iD-3cttA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ILE A 440
ALA A 291
GLY A 439
LEU A 637
PRO A 287
 None
None
None
None
GOL  A3002 (-4.0A)
 1.08A 2y7hB-3cttA:
undetectable		 2y7hB-3cttA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ILE A 440
ALA A 291
GLY A 439
LEU A 637
PRO A 287
 None
None
None
None
GOL  A3002 (-4.0A)
 1.08A 2y7hC-3cttA:
undetectable		 2y7hC-3cttA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_B_VDYB6178_1
(VITAMIN D
HYDROXYLASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 PRO A 320
LEU A 319
ILE A 572
THR A 579
LEU A 619
 None
 1.26A 3a51B-3cttA:
undetectable		 3a51B-3cttA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 THR A 821
ILE A 756
LEU A 758
ILE A 853
VAL A 798
 None
 1.06A 3a51C-3cttA:
undetectable		 3a51C-3cttA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 GLU A 658
ARG A 730
ALA A 757
PHE A 735
TYR A 636
 None
 1.45A 3apwB-3cttA:
undetectable		 3apwB-3cttA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		3 / 3 THR A 204
GLU A 182
HIS A 185
 None
 0.78A 3g1uB-3cttA:
undetectable		 3g1uB-3cttA:
18.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3L4W_A_MIGA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		11 / 12 TYR A 299
ASP A 327
ILE A 328
ILE A 364
TRP A 406
TRP A 441
ASP A 443
MET A 444
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-3.6A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.49A 3l4wA-3cttA:
60.8		 3l4wA-3cttA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3L4W_A_MIGA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		11 / 12 TYR A 299
ASP A 327
ILE A 328
ILE A 364
TRP A 441
ASP A 443
MET A 444
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-3.6A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.19A 3l4wA-3cttA:
60.8		 3l4wA-3cttA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		3 / 3 GLU A 436
GLU A 349
ASN A 352
 None
 0.90A 3lp9B-3cttA:
2.0
3lp9D-3cttA:
2.0		 3lp9B-3cttA:
14.92
3lp9D-3cttA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		11 / 12 ASP A 203
ASP A 327
ILE A 328
ILE A 364
TRP A 406
ASP A 443
ARG A 526
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.45A 3phaA-3cttA:
35.5		 3phaA-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ASP A 203
ASP A 327
ILE A 364
ARG A 526
ASP A 542
PHE A 575
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
 1.44A 3phaA-3cttA:
35.5		 3phaA-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ASP A 542
ASP A 366
ILE A 364
ILE A 328
ASP A 203
 3CU  A1001 ( 2.5A)
None
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
GOL  A3001 (-2.6A)
 1.17A 3phaA-3cttA:
35.5		 3phaA-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ASP A 327
ILE A 328
ILE A 364
TRP A 406
ASP A 443
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.48A 3phaB-3cttA:
40.9		 3phaB-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ASP A 542
ASP A 366
ILE A 364
ILE A 328
ASP A 203
 3CU  A1001 ( 2.5A)
None
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
GOL  A3001 (-2.6A)
 1.18A 3phaB-3cttA:
40.9		 3phaB-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_C_ACRC701_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ASP A 327
ILE A 328
TRP A 406
ASP A 443
ARG A 526
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.43A 3phaC-3cttA:
40.8		 3phaC-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_C_ACRC701_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ASP A 203
ASP A 327
ILE A 364
ARG A 526
ASP A 542
PHE A 575
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
 1.39A 3phaC-3cttA:
40.8		 3phaC-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ASP A 327
ILE A 328
TRP A 406
ASP A 443
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.44A 3phaD-3cttA:
41.2		 3phaD-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ASP A 203
ASP A 327
ILE A 364
MET A 444
ASP A 542
PHE A 575
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
 1.43A 3phaD-3cttA:
41.2		 3phaD-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 327
ILE A 328
ILE A 364
TRP A 406
MET A 444
ARG A 526
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.48A 3pocA-3cttA:
40.9		 3pocA-3cttA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 327
ILE A 328
ILE A 364
TRP A 406
TRP A 441
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-4.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.93A 3pocA-3cttA:
40.9		 3pocA-3cttA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 327
ILE A 364
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.45A 3pocA-3cttA:
40.9		 3pocA-3cttA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB664_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 327
ILE A 328
ILE A 364
TRP A 406
MET A 444
ARG A 526
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.49A 3pocB-3cttA:
42.1		 3pocB-3cttA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB664_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 327
ILE A 328
ILE A 364
TRP A 406
TRP A 441
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-4.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.97A 3pocB-3cttA:
42.1		 3pocB-3cttA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB664_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 327
ILE A 364
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.47A 3pocB-3cttA:
42.1		 3pocB-3cttA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 7 ILE A 816
ILE A 756
VAL A 791
LEU A 796
 None
 0.68A 3r9vA-3cttA:
undetectable
3r9vB-3cttA:
undetectable		 3r9vA-3cttA:
16.09
3r9vB-3cttA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		3 / 3 PHE A 234
GLN A  92
PHE A 529
 None
 0.81A 3rv5A-3cttA:
undetectable		 3rv5A-3cttA:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_2
(PROTEASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 11 LEU A 754
ALA A 764
ASP A 759
ILE A 816
ILE A 756
 None
 0.95A 3s45B-3cttA:
undetectable		 3s45B-3cttA:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_2
(HIV-1 PROTEASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 7 ASN A 832
GLY A 861
ILE A 800
THR A 865
 None
 0.84A 3spkB-3cttA:
undetectable		 3spkB-3cttA:
7.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TOP_A_ACRA1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ASP A 327
ILE A 364
TRP A 406
ASP A 443
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.52A 3topA-3cttA:
48.7		 3topA-3cttA:
43.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TOP_A_ACRA1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 PRO A 206
ASP A 327
ILE A 364
ASP A 443
PHE A 575
HIS A 600
 None
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.29A 3topA-3cttA:
48.7		 3topA-3cttA:
43.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TOP_A_ACRA1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 TRP A 406
MET A 444
ARG A 526
ASP A 542
PHE A 575
 None
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
 1.20A 3topA-3cttA:
48.7		 3topA-3cttA:
43.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TOP_A_ACRA1_2
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 5 ILE A 328
TRP A 441
TRP A 539
THR A 544
 3CU  A1001 ( 3.9A)
3CU  A1001 (-4.9A)
3CU  A1001 (-4.6A)
None
 0.21A 3topA-3cttA:
48.6		 3topA-3cttA:
43.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TOP_B_ACRB1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ASP A 327
ILE A 364
TRP A 406
ASP A 443
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.51A 3topB-3cttA:
48.7		 3topB-3cttA:
43.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASN A 207
ASP A 327
ILE A 364
TRP A 441
ASP A 443
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 None
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.71A 3w37A-3cttA:
47.9		 3w37A-3cttA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ASP A 327
ILE A 364
TRP A 441
ASP A 443
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.33A 3w37A-3cttA:
47.9		 3w37A-3cttA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ASN A 207
ASP A 327
ILE A 328
ASP A 542
PHE A 575
 None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
 1.43A 3welA-3cttA:
48.1		 3welA-3cttA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		9 / 12 ASN A 207
ASP A 327
ILE A 364
TRP A 441
ASP A 443
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 None
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.71A 3welA-3cttA:
48.1		 3welA-3cttA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		9 / 12 ASP A 203
ASP A 327
ILE A 364
TRP A 441
ASP A 443
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.33A 3welA-3cttA:
48.1		 3welA-3cttA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEL_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 6 ILE A 328
TRP A 406
MET A 444
TRP A 539
 3CU  A1001 ( 3.9A)
None
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.6A)
 0.45A 3welA-3cttA:
48.1		 3welA-3cttA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ASN A 207
ASP A 327
ILE A 328
ASP A 443
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.71A 3wemA-3cttA:
47.4		 3wemA-3cttA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEN_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		11 / 12 ASP A 203
ASN A 207
ASP A 327
ILE A 328
TRP A 441
ASP A 443
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.69A 3wenA-3cttA:
47.5		 3wenA-3cttA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ASN A 207
ASP A 327
ILE A 328
TRP A 441
ASP A 443
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.71A 3weoA-3cttA:
55.0		 3weoA-3cttA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEO_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 6 ILE A 364
TRP A 406
MET A 444
TRP A 539
 3CU  A1001 (-4.5A)
None
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.6A)
 0.47A 3weoA-3cttA:
55.0		 3weoA-3cttA:
36.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		3 / 3 GLU A 823
TYR A 844
SER A 846
 None
 0.75A 4at0A-3cttA:
undetectable		 4at0A-3cttA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B9Z_A_ACRA1818_1
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ASP A 327
ILE A 328
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.34A 4b9zA-3cttA:
36.9		 4b9zA-3cttA:
26.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B9Z_A_ACRA1818_1
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 327
ILE A 364
ASP A 443
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.37A 4b9zA-3cttA:
36.9		 4b9zA-3cttA:
26.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 4 ASN A 201
ALA A 216
GLY A 215
THR A 528
 None
 1.29A 4bboC-3cttA:
undetectable		 4bboC-3cttA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 11 ILE A 199
ALA A 216
GLY A 215
GLU A 446
ASN A 498
 None
 1.27A 4e47C-3cttA:
undetectable		 4e47C-3cttA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ASP A 443
ASP A 203
ASP A 571
GLU A 182
HIS A 538
 3CU  A1001 (-2.7A)
GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
None
None
 1.31A 4feuA-3cttA:
0.5
4feuB-3cttA:
undetectable		 4feuA-3cttA:
15.32
4feuB-3cttA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 11 HIS A 538
ASP A 443
ASP A 203
ASP A 571
GLU A 182
 None
3CU  A1001 (-2.7A)
GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
None
 1.40A 4fevE-3cttA:
0.0		 4fevE-3cttA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 11 SER A 297
ASP A 203
ASP A 571
ASP A 542
HIS A 538
 None
GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
3CU  A1001 ( 2.5A)
None
 1.44A 4fewE-3cttA:
0.5
4fewF-3cttA:
0.5		 4fewE-3cttA:
15.32
4fewF-3cttA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 11 SER A 297
ASP A 443
ASP A 203
ASP A 571
HIS A 538
 None
3CU  A1001 (-2.7A)
GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
None
 1.28A 4fewE-3cttA:
0.5
4fewF-3cttA:
0.5		 4fewE-3cttA:
15.32
4fewF-3cttA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		3 / 3 ARG A 471
TYR A 214
ASN A 498
 None
 0.73A 4ffwB-3cttA:
undetectable		 4ffwB-3cttA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 9 GLU A 559
GLY A 179
GLU A 276
TYR A 277
GLY A 232
 None
 1.39A 4fimA-3cttA:
undetectable		 4fimA-3cttA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 6 PRO A 367
ILE A 440
TYR A 415
PHE A 428
 None
 1.18A 4g10A-3cttA:
undetectable		 4g10A-3cttA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 11 ASP A 443
ASP A 203
ASP A 571
GLU A 182
HIS A 538
 3CU  A1001 (-2.7A)
GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
None
None
 1.48A 4gkhC-3cttA:
1.7
4gkhD-3cttA:
0.0		 4gkhC-3cttA:
15.32
4gkhD-3cttA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_H_KANH301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 10 HIS A 538
ASP A 443
ASP A 203
ASP A 571
GLU A 182
 None
3CU  A1001 (-2.7A)
GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
None
 1.38A 4gkhG-3cttA:
0.0
4gkhH-3cttA:
1.5		 4gkhG-3cttA:
15.32
4gkhH-3cttA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_I_KANI301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 11 ASP A 443
ASP A 203
ASP A 571
GLU A 182
HIS A 538
 3CU  A1001 (-2.7A)
GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
None
None
 1.48A 4gkhI-3cttA:
0.0
4gkhJ-3cttA:
0.0		 4gkhI-3cttA:
15.32
4gkhJ-3cttA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_L_KANL301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 10 HIS A 538
ASP A 443
ASP A 203
ASP A 571
GLU A 182
 None
3CU  A1001 (-2.7A)
GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
None
 1.35A 4gkhK-3cttA:
0.2
4gkhL-3cttA:
1.5		 4gkhK-3cttA:
15.32
4gkhL-3cttA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 11 HIS A 538
ASP A 443
ASP A 203
ASP A 571
GLU A 182
 None
3CU  A1001 (-2.7A)
GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
None
 1.39A 4gkiC-3cttA:
0.0
4gkiD-3cttA:
1.5		 4gkiC-3cttA:
15.32
4gkiD-3cttA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_L_KANL301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 HIS A 538
ASP A 443
ASP A 203
ASP A 571
GLU A 182
 None
3CU  A1001 (-2.7A)
GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
None
 1.50A 4gkiK-3cttA:
1.7
4gkiL-3cttA:
1.7		 4gkiK-3cttA:
15.32
4gkiL-3cttA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 8 SER A 395
LEU A 401
SER A 394
THR A 399
 None
 0.88A 4iklA-3cttA:
undetectable
4iklB-3cttA:
undetectable		 4iklA-3cttA:
10.35
4iklB-3cttA:
10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 11 ILE A 199
ALA A 216
GLY A 215
GLU A 446
ASN A 498
 None
 1.28A 4jdsC-3cttA:
undetectable		 4jdsC-3cttA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 8 THR A 218
LEU A 245
VAL A 243
VAL A 233
 None
 1.08A 4l4eA-3cttA:
undetectable		 4l4eA-3cttA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 8 THR A 218
LEU A 245
VAL A 243
VAL A 233
 None
 1.10A 4l4fA-3cttA:
undetectable		 4l4fA-3cttA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OMW_D_TE4D202_1
(BETA-LACTOGLOBULIN)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 9 PRO A 367
GLU A 446
ASN A 201
ALA A 216
SER A 527
 None
 1.48A 4omwD-3cttA:
undetectable		 4omwD-3cttA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA601_1
(SERUM ALBUMIN)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ASN A 599
PHE A 294
LEU A 319
LEU A 619
SER A 612
 None
 1.06A 4po0A-3cttA:
undetectable		 4po0A-3cttA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 5 PHE A 529
PRO A 112
VAL A 111
PHE A 109
 None
 1.18A 4w5oA-3cttA:
undetectable		 4w5oA-3cttA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 LEU A 754
ALA A 764
ASP A 759
ILE A 816
ILE A 756
 None
 0.83A 5e5jA-3cttA:
undetectable		 5e5jA-3cttA:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 LEU A 754
ALA A 764
ASP A 759
ILE A 816
ILE A 756
 None
 0.84A 5e5kB-3cttA:
undetectable		 5e5kB-3cttA:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 LEU A 401
PRO A 400
ILE A 390
GLY A 385
ASP A 387
 None
 1.12A 5h5fA-3cttA:
undetectable		 5h5fA-3cttA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ILE A 818
ALA A 851
GLY A 732
GLY A 820
VAL A 791
 None
 0.94A 5i73A-3cttA:
undetectable		 5i73A-3cttA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEF_A_NBVA1005_1
(NEUTRAL
ALPHA-GLUCOSIDASE AB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 327
ILE A 328
ILE A 364
TRP A 441
ASP A 443
MET A 444
PHE A 450
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
None
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.47A 5iefA-3cttA:
49.1		 5iefA-3cttA:
29.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEF_A_NBVA1005_2
(NEUTRAL
ALPHA-GLUCOSIDASE AB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 4 ARG A 526
TRP A 539
ASP A 571
ARG A 598
 3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 4.8A)
3CU  A1001 ( 4.7A)
 0.41A 5iefA-3cttA:
49.1		 5iefA-3cttA:
29.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 5 ARG A 144
LEU A 151
PHE A 152
LEU A 266
 None
 1.20A 5iy5P-3cttA:
undetectable
5iy5W-3cttA:
undetectable		 5iy5P-3cttA:
14.24
5iy5W-3cttA:
4.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 VAL A 779
LEU A 292
SER A 646
GLN A 738
LEU A 768
 None
 1.19A 5m50E-3cttA:
undetectable		 5m50E-3cttA:
18.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NN6_A_MIGA1013_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 327
ILE A 364
TRP A 406
TRP A 441
ASP A 443
MET A 444
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.71A 5nn6A-3cttA:
51.5		 5nn6A-3cttA:
44.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NN8_A_ACRA1015_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ASP A 327
ILE A 364
TRP A 406
TRP A 441
ASP A 443
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.40A 5nn8A-3cttA:
54.9		 5nn8A-3cttA:
44.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NN8_A_ACRA1015_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ASP A 203
ASP A 571
ASP A 542
ASP A 443
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-2.7A)
3CU  A1001 (-3.9A)
 1.44A 5nn8A-3cttA:
54.9		 5nn8A-3cttA:
44.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 6 PHE A 529
PRO A 112
VAL A 111
PHE A 109
 None
 1.16A 5t7bA-3cttA:
undetectable		 5t7bA-3cttA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		3 / 3 TRP A 423
MET A 388
ASN A 419
 None
 1.31A 5uc1B-3cttA:
undetectable		 5uc1B-3cttA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		3 / 3 TRP A 423
MET A 388
ASN A 419
 None
 1.37A 5uc1A-3cttA:
undetectable		 5uc1A-3cttA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 8 ILE A 369
TYR A 500
TRP A 424
VAL A 365
 None
 0.91A 5vlmF-3cttA:
undetectable		 5vlmF-3cttA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 7 GLY A 602
TRP A 406
ASP A 329
TYR A 301
 None
 1.17A 5vlmG-3cttA:
undetectable		 5vlmG-3cttA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 6 ARG A 144
LEU A 151
PHE A 152
LEU A 266
 None
 1.12A 5w97C-3cttA:
undetectable
5w97J-3cttA:
undetectable		 5w97C-3cttA:
14.24
5w97J-3cttA:
5.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 6 ARG A 144
LEU A 151
PHE A 152
LEU A 266
 None
 1.05A 5x19P-3cttA:
undetectable		 5x19P-3cttA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 5 ARG A 144
LEU A 151
PHE A 152
LEU A 266
 None
 1.10A 5x1bP-3cttA:
undetectable		 5x1bP-3cttA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 5 ARG A 144
LEU A 151
PHE A 152
LEU A 266
 None
 1.14A 5x1fC-3cttA:
undetectable
5x1fJ-3cttA:
undetectable		 5x1fC-3cttA:
14.24
5x1fJ-3cttA:
5.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1401_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 10 TRP A 441
ASP A 443
ARG A 526
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.50A 5x7pA-3cttA:
32.8		 5x7pA-3cttA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 5 ARG A 144
LEU A 151
PHE A 152
LEU A 266
 None
 1.18A 5xdxC-3cttA:
undetectable
5xdxJ-3cttA:
undetectable		 5xdxC-3cttA:
14.59
5xdxJ-3cttA:
5.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 5 ARG A 144
LEU A 151
PHE A 152
LEU A 266
 None
 1.21A 5xdxP-3cttA:
undetectable
5xdxW-3cttA:
undetectable		 5xdxP-3cttA:
14.59
5xdxW-3cttA:
5.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 SER A 622
ILE A 629
LEU A 727
HIS A 625
LEU A 720
 None
None
None
SO4  A4001 (-3.9A)
None
 1.42A 5zwrB-3cttA:
undetectable		 5zwrB-3cttA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_B_SAMB505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 TRP A 674
ILE A 554
HIS A 538
LEU A 540
GLY A 556
 None
 1.36A 6bp4B-3cttA:
undetectable		 6bp4B-3cttA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 8 LEU A 499
TYR A 502
GLU A 114
TRP A 490
 None
 1.05A 6c71B-3cttA:
undetectable		 6c71B-3cttA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ILE A 328
ILE A 364
TRP A 406
ASP A 443
MET A 444
ARG A 526
TRP A 539
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.40A 6c9xA-3cttA:
35.7		 6c9xA-3cttA:
25.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ASP A 203
ILE A 364
MET A 444
ARG A 526
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.28A 6c9xA-3cttA:
35.7		 6c9xA-3cttA:
25.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ILE A 328
ILE A 364
TRP A 406
TRP A 441
PHE A 575
HIS A 600
 3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-4.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.93A 6c9xA-3cttA:
35.7		 6c9xA-3cttA:
25.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ILE A 328
ILE A 364
TRP A 406
ASP A 443
MET A 444
ARG A 526
TRP A 539
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.41A 6c9xB-3cttA:
35.7		 6c9xB-3cttA:
25.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ASP A 203
ILE A 364
MET A 444
ARG A 526
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.27A 6c9xB-3cttA:
35.7		 6c9xB-3cttA:
25.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ILE A 328
ILE A 364
TRP A 406
TRP A 441
PHE A 575
HIS A 600
 3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-4.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.94A 6c9xB-3cttA:
35.7		 6c9xB-3cttA:
25.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ILE A 328
MET A 444
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.50A 6c9zA-3cttA:
34.3		 6c9zA-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ILE A 364
MET A 444
ARG A 526
ASP A 542
PHE A 575
 3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
 1.00A 6c9zA-3cttA:
34.3		 6c9zA-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		11 / 12 TYR A 299
ILE A 328
ILE A 364
TRP A 406
ASP A 443
MET A 444
ARG A 526
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-3.6A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.53A 6c9zA-3cttA:
34.3		 6c9zA-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 TYR A 299
ILE A 328
ILE A 364
TRP A 406
TRP A 441
PHE A 575
HIS A 600
 3CU  A1001 (-3.6A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-4.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.03A 6c9zA-3cttA:
34.3		 6c9zA-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ASP A 203
ILE A 328
MET A 444
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.44A 6c9zB-3cttA:
35.5		 6c9zB-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ASP A 203
ILE A 364
MET A 444
ARG A 526
PHE A 575
 GOL  A3001 (-2.6A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.5A)
 1.10A 6c9zB-3cttA:
35.5		 6c9zB-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		11 / 12 ASP A 203
TYR A 299
ILE A 328
ILE A 364
TRP A 406
ASP A 443
MET A 444
ARG A 526
TRP A 539
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-3.6A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.52A 6c9zB-3cttA:
35.5		 6c9zB-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 TYR A 299
ILE A 328
ILE A 364
TRP A 406
TRP A 441
PHE A 575
HIS A 600
 3CU  A1001 (-3.6A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-4.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.02A 6c9zB-3cttA:
35.5		 6c9zB-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 327
ILE A 328
ILE A 364
ASP A 443
MET A 444
ARG A 526
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.40A 6ca1A-3cttA:
40.8		 6ca1A-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ASP A 327
ILE A 328
ILE A 364
TRP A 441
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-4.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.77A 6ca1A-3cttA:
40.8		 6ca1A-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 327
ILE A 364
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.41A 6ca1A-3cttA:
40.8		 6ca1A-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 327
ILE A 328
ILE A 364
ASP A 443
MET A 444
ARG A 526
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.40A 6ca1B-3cttA:
39.4		 6ca1B-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ASP A 327
ILE A 328
ILE A 364
TRP A 441
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-4.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.79A 6ca1B-3cttA:
39.4		 6ca1B-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 327
ILE A 364
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.44A 6ca1B-3cttA:
39.4		 6ca1B-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ASP A 327
ILE A 364
MET A 444
ARG A 526
ASP A 542
PHE A 575
 3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
 1.47A 6ca3A-3cttA:
35.7		 6ca3A-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		11 / 12 TYR A 299
ASP A 327
ILE A 328
ILE A 364
ASP A 443
MET A 444
ARG A 526
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-3.6A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.47A 6ca3A-3cttA:
35.7		 6ca3A-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 TYR A 299
ASP A 327
ILE A 328
ILE A 364
TRP A 441
PHE A 575
HIS A 600
 3CU  A1001 (-3.6A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-4.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.89A 6ca3A-3cttA:
35.7		 6ca3A-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 327
ILE A 328
ILE A 364
ASP A 443
MET A 444
ARG A 526
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.42A 6ca3B-3cttA:
34.4		 6ca3B-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		8 / 12 ASP A 327
ILE A 328
ILE A 364
TRP A 406
ASP A 443
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.78A 6ca3B-3cttA:
34.4		 6ca3B-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 327
ILE A 328
ILE A 364
TRP A 406
TRP A 441
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-4.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.25A 6ca3B-3cttA:
34.4		 6ca3B-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ASP A 327
ILE A 364
MET A 444
ARG A 526
ASP A 542
PHE A 575
 3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
 1.47A 6ca3B-3cttA:
34.4		 6ca3B-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_0
(PROTEASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 LEU A 754
ALA A 764
ASP A 759
ILE A 816
ILE A 756
 None
 0.78A 6dh3A-3cttA:
undetectable		 6dh3A-3cttA:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 6 LEU A  87
TYR A 263
GLN A 117
GLU A  90
 None
 1.25A 6djzC-3cttA:
1.3		 6djzC-3cttA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		3 / 3 ARG A 144
LEU A 151
PHE A 152
 None
 0.80A 6nknP-3cttA:
undetectable		 6nknP-3cttA:
14.24