SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cu3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WRL_A_TFPA204_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	3cu3	DOMAIN OF UNKNOWN FUNCTION WITH A CYSTATIN-LIKE FOLD (Nostoc punctiforme)	4 / 7	PHE A 36 LEU A 77 PHE A 40 VAL A 119	None	0.88A	1wrlA-3cu3A: undetectable 1wrlB-3cu3A: undetectable	1wrlA-3cu3A: 22.35 1wrlB-3cu3A: 22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Y0X_X_T44X500_1 (THYROID HORMONE RECEPTOR BETA-1)	3cu3	DOMAIN OF UNKNOWN FUNCTION WITH A CYSTATIN-LIKE FOLD (Nostoc punctiforme)	5 / 12	ILE A 98 MET A 24 ARG A 18 LEU A 132 ILE A 129	None	1.36A	1y0xX-3cu3A: undetectable	1y0xX-3cu3A: 21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RTB_A_SAMA501_0 (HYDG PROTEIN)	3cu3	DOMAIN OF UNKNOWN FUNCTION WITH A CYSTATIN-LIKE FOLD (Nostoc punctiforme)	5 / 12	LEU A 152 PHE A 149 LEU A 146 LEU A 138 ALA A 110	None	1.44A	4rtbA-3cu3A: undetectable	4rtbA-3cu3A: 16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RTB_A_SAMA501_0 (HYDG PROTEIN)	3cu3	DOMAIN OF UNKNOWN FUNCTION WITH A CYSTATIN-LIKE FOLD (Nostoc punctiforme)	5 / 12	VAL A 164 PHE A 149 LEU A 146 LEU A 138 ALA A 110	None	1.20A	4rtbA-3cu3A: undetectable	4rtbA-3cu3A: 16.74

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1WRL_A_TFPA204_1","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES;TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","3cu3","DOMAIN OF UNKNOWN FUNCTION WITH A CYSTATIN-LIKE FOLD","Nostoc punctiforme",4,"PHE A  36;LEU A  77;PHE A  40;VAL A 119","None","0.88A","1wrlA-3cu3A:undetectable;1wrlB-3cu3A:undetectable","1wrlA-3cu3A:22.35;1wrlB-3cu3A:22.35"],["1Y0X_X_T44X500_1","THYROID HORMONE RECEPTOR BETA-1","3cu3","DOMAIN OF UNKNOWN FUNCTION WITH A CYSTATIN-LIKE FOLD","Nostoc punctiforme",5,"ILE A  98;MET A  24;ARG A  18;LEU A 132;ILE A 129","None","1.36A","1y0xX-3cu3A:undetectable","1y0xX-3cu3A:21.71"],["4RTB_A_SAMA501_0","HYDG PROTEIN","3cu3","DOMAIN OF UNKNOWN FUNCTION WITH A CYSTATIN-LIKE FOLD","Nostoc punctiforme",5,"LEU A 152;PHE A 149;LEU A 146;LEU A 138;ALA A 110","None","1.44A","4rtbA-3cu3A:undetectable","4rtbA-3cu3A:16.74"],["4RTB_A_SAMA501_0","HYDG PROTEIN","3cu3","DOMAIN OF UNKNOWN FUNCTION WITH A CYSTATIN-LIKE FOLD","Nostoc punctiforme",5,"VAL A 164;PHE A 149;LEU A 146;LEU A 138;ALA A 110","None","1.20A","4rtbA-3cu3A:undetectable","4rtbA-3cu3A:16.74"]]