SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cuc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 3cuc PROTEIN OF UNKNOWN
FUNCTION WITH A FIC
DOMAIN
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 182
ASN A 207
ILE A   6
ILE A 266
LEU A 210
 None
 1.29A 2bjfA-3cucA:
undetectable		 2bjfA-3cucA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A933_1
(ANDROGEN RECEPTOR)		 3cuc PROTEIN OF UNKNOWN
FUNCTION WITH A FIC
DOMAIN
(Bacteroides
thetaiotaomicron) 		5 / 10 PHE A  98
GLY A  79
ASN A  77
GLU A  86
ARG A  92
 None
 1.43A 2piwA-3cucA:
2.0		 2piwA-3cucA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 3cuc PROTEIN OF UNKNOWN
FUNCTION WITH A FIC
DOMAIN
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 210
TYR A 260
LEU A 261
CYH A 264
LEU A 265
 None
 1.39A 3okxA-3cucA:
undetectable		 3okxA-3cucA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X30_A_T44A401_1
(THYROXINE-BINDING
GLOBULIN)		 3cuc PROTEIN OF UNKNOWN
FUNCTION WITH A FIC
DOMAIN
(Bacteroides
thetaiotaomicron) 		5 / 9 ALA A  65
LEU A  56
LEU A  47
ASN A  40
LEU A  55
 None
 1.49A 4x30A-3cucA:
undetectable		 4x30A-3cucA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 3cuc PROTEIN OF UNKNOWN
FUNCTION WITH A FIC
DOMAIN
(Bacteroides
thetaiotaomicron) 		3 / 3 LYS A  12
TRP A  13
SER A  15
 None
 0.99A 5nwwA-3cucA:
undetectable		 5nwwA-3cucA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3cuc PROTEIN OF UNKNOWN
FUNCTION WITH A FIC
DOMAIN
(Bacteroides
thetaiotaomicron) 		4 / 8 TRP A  27
THR A 270
GLN A  17
TRP A  13
 None
 1.41A 5tzoC-3cucA:
undetectable		 5tzoC-3cucA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3cuc PROTEIN OF UNKNOWN
FUNCTION WITH A FIC
DOMAIN
(Bacteroides
thetaiotaomicron) 		5 / 10 ILE A 220
ILE A 218
LEU A 210
HIS A 192
ILE A 189
 None
 1.18A 5vkqA-3cucA:
undetectable
5vkqD-3cucA:
undetectable		 5vkqA-3cucA:
11.06
5vkqD-3cucA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3cuc PROTEIN OF UNKNOWN
FUNCTION WITH A FIC
DOMAIN
(Bacteroides
thetaiotaomicron) 		5 / 10 HIS A 192
ILE A 189
ILE A 220
ILE A 218
LEU A 210
 None
 1.16A 5vkqA-3cucA:
undetectable
5vkqB-3cucA:
undetectable		 5vkqA-3cucA:
11.06
5vkqB-3cucA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3cuc PROTEIN OF UNKNOWN
FUNCTION WITH A FIC
DOMAIN
(Bacteroides
thetaiotaomicron) 		5 / 10 HIS A 192
ILE A 189
ILE A 220
ILE A 218
LEU A 210
 None
 1.17A 5vkqC-3cucA:
undetectable
5vkqD-3cucA:
undetectable		 5vkqC-3cucA:
11.06
5vkqD-3cucA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)		 3cuc PROTEIN OF UNKNOWN
FUNCTION WITH A FIC
DOMAIN
(Bacteroides
thetaiotaomicron) 		4 / 6 LYS A  68
GLU A  72
ALA A  75
LYS A  74
 None
 1.19A 6an0A-3cucA:
undetectable		 6an0A-3cucA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 3cuc PROTEIN OF UNKNOWN
FUNCTION WITH A FIC
DOMAIN
(Bacteroides
thetaiotaomicron) 		5 / 10 HIS A 185
ALA A 182
TYR A 260
GLU A 223
PHE A  35
 None
 1.48A 6b89A-3cucA:
0.0		 6b89A-3cucA:
14.69