SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cuo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 3cuo UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YGAV
(Escherichia
coli) 		5 / 12 LEU A  33
LEU A  30
LEU A  27
LEU A  59
THR A  39
 None
 1.27A 1a28B-3cuoA:
undetectable		 1a28B-3cuoA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3cuo UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YGAV
(Escherichia
coli) 		5 / 12 GLY A  42
ALA A  41
SER A  40
GLY A  38
LEU A  78
 None
 0.94A 1fe2A-3cuoA:
undetectable		 1fe2A-3cuoA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_2
(BETA-LACTAMASE
CTX-M-9)		 3cuo UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YGAV
(Escherichia
coli) 		4 / 5 TYR A  79
PRO A  37
THR A  55
THR A  45
 None
 1.35A 1ymxB-3cuoA:
undetectable		 1ymxB-3cuoA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3cuo UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YGAV
(Escherichia
coli) 		5 / 12 GLY A  42
ALA A  41
SER A  40
GLY A  38
LEU A  78
 None
 1.02A 4e1gA-3cuoA:
undetectable		 4e1gA-3cuoA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3cuo UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YGAV
(Escherichia
coli) 		5 / 12 GLY A  42
ALA A  41
SER A  40
GLY A  38
LEU A  78
 None
 1.02A 4e1gB-3cuoA:
undetectable		 4e1gB-3cuoA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_C_08JC602_1
(CYTOCHROME P450 3A4)		 3cuo UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YGAV
(Escherichia
coli) 		4 / 7 ARG A  63
ALA A  41
ILE A  29
LEU A  33
 None
 0.87A 5te8C-3cuoA:
undetectable		 5te8C-3cuoA:
12.80