SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cvd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3cvd PLASTOCYANIN
(Phormidium
laminosum) 		4 / 4 HIS A  39
CYH A  89
HIS A  92
MET A  97
 CU1  A 106 (-3.1A)
CU1  A 106 (-2.2A)
CU1  A 106 (-3.9A)
CU1  A 106 (-2.4A)
 0.46A 1oe1A-3cvdA:
undetectable		 1oe1A-3cvdA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3cvd PLASTOCYANIN
(Phormidium
laminosum) 		5 / 5 HIS A  39
CYH A  89
PRO A  91
HIS A  92
MET A  97
 CU1  A 106 (-3.1A)
CU1  A 106 (-2.2A)
None
CU1  A 106 (-3.9A)
CU1  A 106 (-2.4A)
 0.81A 1oe2A-3cvdA:
6.0		 1oe2A-3cvdA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3cvd PLASTOCYANIN
(Phormidium
laminosum) 		4 / 4 HIS A  39
CYH A  89
HIS A  92
MET A  97
 CU1  A 106 (-3.1A)
CU1  A 106 (-2.2A)
CU1  A 106 (-3.9A)
CU1  A 106 (-2.4A)
 0.47A 1oe3A-3cvdA:
2.8		 1oe3A-3cvdA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3cvd PLASTOCYANIN
(Phormidium
laminosum) 		4 / 4 HIS A  39
CYH A  89
HIS A  92
MET A  97
 CU1  A 106 (-3.1A)
CU1  A 106 (-2.2A)
CU1  A 106 (-3.9A)
CU1  A 106 (-2.4A)
 0.33A 2fqdA-3cvdA:
undetectable		 2fqdA-3cvdA:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3cvd PLASTOCYANIN
(Phormidium
laminosum) 		4 / 4 HIS A  39
CYH A  89
HIS A  92
MET A  97
 CU1  A 106 (-3.1A)
CU1  A 106 (-2.2A)
CU1  A 106 (-3.9A)
CU1  A 106 (-2.4A)
 0.37A 2fqeA-3cvdA:
undetectable		 2fqeA-3cvdA:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3cvd PLASTOCYANIN
(Phormidium
laminosum) 		4 / 4 HIS A  39
CYH A  89
HIS A  92
MET A  97
 CU1  A 106 (-3.1A)
CU1  A 106 (-2.2A)
CU1  A 106 (-3.9A)
CU1  A 106 (-2.4A)
 0.39A 2fqfA-3cvdA:
undetectable		 2fqfA-3cvdA:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3cvd PLASTOCYANIN
(Phormidium
laminosum) 		4 / 4 HIS A  39
CYH A  89
HIS A  92
MET A  97
 CU1  A 106 (-3.1A)
CU1  A 106 (-2.2A)
CU1  A 106 (-3.9A)
CU1  A 106 (-2.4A)
 0.38A 2fqgA-3cvdA:
undetectable		 2fqgA-3cvdA:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3cvd PLASTOCYANIN
(Phormidium
laminosum) 		4 / 4 HIS A  39
CYH A  89
HIS A  92
MET A  97
 CU1  A 106 (-3.1A)
CU1  A 106 (-2.2A)
CU1  A 106 (-3.9A)
CU1  A 106 (-2.4A)
 0.42A 2xxgA-3cvdA:
6.0		 2xxgA-3cvdA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3cvd PLASTOCYANIN
(Phormidium
laminosum) 		5 / 5 HIS A  39
CYH A  89
PRO A  91
HIS A  92
MET A  97
 CU1  A 106 (-3.1A)
CU1  A 106 (-2.2A)
None
CU1  A 106 (-3.9A)
CU1  A 106 (-2.4A)
 0.86A 2xxgC-3cvdA:
6.1		 2xxgC-3cvdA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 3cvd PLASTOCYANIN
(Phormidium
laminosum) 		3 / 3 GLY A  99
TRP A  31
VAL A   5
 None
 0.64A 3n62B-3cvdA:
undetectable		 3n62B-3cvdA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 3cvd PLASTOCYANIN
(Phormidium
laminosum) 		3 / 3 GLY A  99
TRP A  31
VAL A   5
 None
 0.66A 3n65B-3cvdA:
undetectable		 3n65B-3cvdA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 3cvd PLASTOCYANIN
(Phormidium
laminosum) 		3 / 3 GLY A  99
TRP A  31
VAL A   5
 None
 0.64A 3n66B-3cvdA:
undetectable		 3n66B-3cvdA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 3cvd PLASTOCYANIN
(Phormidium
laminosum) 		4 / 4 HIS A  39
CYH A  89
HIS A  92
MET A  97
 CU1  A 106 (-3.1A)
CU1  A 106 (-2.2A)
CU1  A 106 (-3.9A)
CU1  A 106 (-2.4A)
 0.35A 4ef3A-3cvdA:
undetectable		 4ef3A-3cvdA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3cvd PLASTOCYANIN
(Phormidium
laminosum) 		4 / 7 LEU A  55
PRO A  81
LEU A  59
TYR A  85
 None
 1.06A 4z4fA-3cvdA:
undetectable		 4z4fA-3cvdA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3cvd PLASTOCYANIN
(Phormidium
laminosum) 		4 / 8 THR A 102
TYR A  85
THR A  86
GLN A  47
 None
 1.19A 5tzoA-3cvdA:
undetectable		 5tzoA-3cvdA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3cvd PLASTOCYANIN
(Phormidium
laminosum) 		4 / 8 THR A 102
TYR A  85
THR A  86
GLN A  47
 None
 1.20A 5tzoB-3cvdA:
undetectable		 5tzoB-3cvdA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3cvd PLASTOCYANIN
(Phormidium
laminosum) 		4 / 8 THR A 102
TYR A  85
THR A  86
GLN A  47
 None
 1.18A 5tzoC-3cvdA:
undetectable		 5tzoC-3cvdA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3cvd PLASTOCYANIN
(Phormidium
laminosum) 		3 / 3 GLY A  99
TRP A  31
VAL A   5
 None
 0.62A 5vuoB-3cvdA:
undetectable		 5vuoB-3cvdA:
14.56