SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cvg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_A_IPHA802_0
(PHENOL HYDROXYLASE)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		5 / 10 GLY A  48
VAL A  53
ILE A  97
TYR A  99
GLY A  45
 None
 1.16A 1fohA-3cvgA:
undetectable		 1fohA-3cvgA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_B_IPHB802_0
(PHENOL HYDROXYLASE)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		5 / 10 GLY A  48
VAL A  53
ILE A  97
TYR A  99
GLY A  45
 None
 1.17A 1fohB-3cvgA:
undetectable		 1fohB-3cvgA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		5 / 12 ALA A 255
TYR A  99
GLY A  43
VAL A  53
LEU A  52
 None
 1.23A 1jipA-3cvgA:
undetectable		 1jipA-3cvgA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		4 / 4 HIS A 151
ASP A 145
SER A 138
ASP A 152
 None
 1.22A 1n2xA-3cvgA:
undetectable		 1n2xA-3cvgA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_2
(PROTEASE)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		5 / 11 ASN A  44
GLY A  46
ALA A  47
ILE A 286
ILE A  97
 None
 0.95A 1n49B-3cvgA:
undetectable		 1n49B-3cvgA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_1
(PROTEASE)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		5 / 11 ASN A  44
GLY A  46
ALA A  47
ILE A 286
ILE A  97
 None
 0.94A 1n49C-3cvgA:
undetectable		 1n49C-3cvgA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N6C_A_SAMA402_0
(SET
DOMAIN-CONTAINING
PROTEIN 7)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		5 / 11 ILE A  97
ALA A  47
GLY A  46
LYS A  78
ASN A  44
 None
 1.21A 1n6cA-3cvgA:
undetectable		 1n6cA-3cvgA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_A_IPHA6012_0
(PHENOL
2-MONOOXYGENASE)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		5 / 10 GLY A  48
VAL A  53
ILE A  97
TYR A  99
GLY A  45
 None
 1.16A 1pn0A-3cvgA:
undetectable		 1pn0A-3cvgA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_B_IPHB6022_0
(PHENOL
2-MONOOXYGENASE)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		5 / 10 GLY A  48
VAL A  53
ILE A  97
TYR A  99
GLY A  45
 None
 1.16A 1pn0B-3cvgA:
undetectable		 1pn0B-3cvgA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		5 / 12 ILE A  42
GLY A  43
VAL A  95
ILE A  85
VAL A  53
 None
 1.01A 3fpjA-3cvgA:
undetectable		 3fpjA-3cvgA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		5 / 12 HIS A 256
GLY A  46
ALA A  47
SER A  50
LEU A  52
 None
 1.26A 3n8xA-3cvgA:
undetectable		 3n8xA-3cvgA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		3 / 3 GLY A  96
THR A  84
ASN A  44
 None
 0.69A 3v4tD-3cvgA:
undetectable		 3v4tD-3cvgA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		5 / 11 ILE A  97
ALA A  47
GLY A  46
LYS A  78
ASN A  44
 None
 1.21A 4e47A-3cvgA:
undetectable		 4e47A-3cvgA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		5 / 11 ILE A  97
ALA A  47
GLY A  46
LYS A  78
ASN A  44
 None
 1.17A 4e47B-3cvgA:
undetectable		 4e47B-3cvgA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		5 / 11 ILE A  97
ALA A  47
GLY A  46
LYS A  78
ASN A  44
 None
 1.22A 4e47C-3cvgA:
undetectable		 4e47C-3cvgA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		5 / 11 ILE A  97
ALA A  47
GLY A  46
LYS A  78
ASN A  44
 None
 1.18A 4jdsA-3cvgA:
undetectable		 4jdsA-3cvgA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		5 / 11 ILE A  97
ALA A  47
GLY A  46
LYS A  78
ASN A  44
 None
 1.18A 4jdsB-3cvgA:
undetectable		 4jdsB-3cvgA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		5 / 11 ILE A  97
ALA A  47
GLY A  46
LYS A  78
ASN A  44
 None
 1.21A 4jdsC-3cvgA:
undetectable		 4jdsC-3cvgA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		5 / 12 ILE A  97
ALA A  47
GLY A  46
LYS A  78
ASN A  44
 None
 1.17A 4jlgA-3cvgA:
undetectable		 4jlgA-3cvgA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		4 / 8 ILE A 143
LEU A 166
ILE A 220
MET A 150
 None
 0.98A 4xtaB-3cvgA:
undetectable		 4xtaB-3cvgA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		5 / 11 ILE A  97
ALA A  47
GLY A  46
LYS A  78
ASN A  44
 None
 1.17A 5ayfA-3cvgA:
undetectable		 5ayfA-3cvgA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C6P_A_4YHA601_1
(PROTEIN C)		 3cvg PUTATIVE METAL
BINDING PROTEIN
(Coccidioides
immitis) 		4 / 6 ALA A 173
SER A 172
GLN A  49
ASP A 123
 CA  A 401 ( 3.8A)
CA  A 401 ( 3.8A)
None
None
 1.22A 5c6pA-3cvgA:
undetectable		 5c6pA-3cvgA:
19.91