SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cvr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		4 / 6 LEU A 348
TRP A 338
LEU A 374
PHE A 312
 None
 1.07A 1ru9H-3cvrA:
undetectable
1ru9L-3cvrA:
undetectable		 1ru9H-3cvrA:
17.88
1ru9L-3cvrA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		4 / 6 LEU A 348
TRP A 338
LEU A 374
PHE A 312
 None
 1.10A 1rukH-3cvrA:
undetectable
1rukL-3cvrA:
undetectable		 1rukH-3cvrA:
17.88
1rukL-3cvrA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_B_CHDB4085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.43A 1v54A-3cvrA:
undetectable
1v54B-3cvrA:
undetectable
1v54T-3cvrA:
undetectable		 1v54A-3cvrA:
22.78
1v54B-3cvrA:
18.50
1v54T-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_O_CHDO3085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.44A 1v54G-3cvrA:
0.0
1v54N-3cvrA:
2.0
1v54O-3cvrA:
0.0		 1v54G-3cvrA:
9.07
1v54N-3cvrA:
22.78
1v54O-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_O_CHDO3085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.43A 1v55G-3cvrA:
undetectable
1v55N-3cvrA:
undetectable
1v55O-3cvrA:
undetectable		 1v55G-3cvrA:
9.07
1v55N-3cvrA:
22.78
1v55O-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		3 / 3 THR A 322
GLU A 447
HIS A 221
 None
 0.80A 1xwfA-3cvrA:
undetectable		 1xwfA-3cvrA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		3 / 3 THR A 322
GLU A 447
HIS A 221
 None
 0.84A 1xwfB-3cvrA:
undetectable		 1xwfB-3cvrA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		3 / 3 THR A 322
GLU A 447
HIS A 221
 None
 0.83A 1xwfC-3cvrA:
undetectable		 1xwfC-3cvrA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		3 / 3 THR A 322
GLU A 447
HIS A 221
 None
 0.87A 1xwfD-3cvrA:
undetectable		 1xwfD-3cvrA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.43A 2dyrG-3cvrA:
0.0
2dyrN-3cvrA:
0.0
2dyrO-3cvrA:
0.0		 2dyrG-3cvrA:
9.07
2dyrN-3cvrA:
22.78
2dyrO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.42A 2eijG-3cvrA:
undetectable
2eijN-3cvrA:
undetectable
2eijO-3cvrA:
undetectable		 2eijG-3cvrA:
9.07
2eijN-3cvrA:
22.78
2eijO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.42A 2eikG-3cvrA:
undetectable
2eikN-3cvrA:
undetectable
2eikO-3cvrA:
undetectable		 2eikG-3cvrA:
9.07
2eikN-3cvrA:
22.78
2eikO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.43A 2eilG-3cvrA:
undetectable
2eilN-3cvrA:
1.8
2eilO-3cvrA:
undetectable		 2eilG-3cvrA:
9.07
2eilN-3cvrA:
22.78
2eilO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CHDN1604_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.48A 2eimG-3cvrA:
undetectable
2eimN-3cvrA:
0.7
2eimO-3cvrA:
undetectable		 2eimG-3cvrA:
9.07
2eimN-3cvrA:
22.78
2eimO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		4 / 5 LEU A 138
PRO A 139
LEU A 142
ILE A 145
 None
 0.73A 2qd4A-3cvrA:
undetectable		 2qd4A-3cvrA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_G_CHDG1085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.42A 2y69G-3cvrA:
0.0
2y69N-3cvrA:
0.5
2y69O-3cvrA:
0.0		 2y69G-3cvrA:
10.14
2y69N-3cvrA:
22.78
2y69O-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_T_CHDT1085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.44A 2y69A-3cvrA:
2.0
2y69B-3cvrA:
0.0
2y69T-3cvrA:
0.0		 2y69A-3cvrA:
22.78
2y69B-3cvrA:
18.50
2y69T-3cvrA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_B_CHDB1086_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.44A 2zxwA-3cvrA:
2.1
2zxwB-3cvrA:
undetectable
2zxwT-3cvrA:
undetectable		 2zxwA-3cvrA:
22.78
2zxwB-3cvrA:
18.50
2zxwT-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_G_CHDG86_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.43A 2zxwG-3cvrA:
undetectable
2zxwN-3cvrA:
0.8
2zxwO-3cvrA:
undetectable		 2zxwG-3cvrA:
9.07
2zxwN-3cvrA:
22.78
2zxwO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.41A 3abkA-3cvrA:
2.1
3abkB-3cvrA:
undetectable
3abkT-3cvrA:
undetectable		 3abkA-3cvrA:
22.78
3abkB-3cvrA:
18.50
3abkT-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.42A 3abkG-3cvrA:
0.0
3abkN-3cvrA:
0.5
3abkO-3cvrA:
0.0		 3abkG-3cvrA:
9.07
3abkN-3cvrA:
22.78
3abkO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_B_CHDB1086_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.45A 3ablA-3cvrA:
0.7
3ablB-3cvrA:
undetectable
3ablT-3cvrA:
undetectable		 3ablA-3cvrA:
22.78
3ablB-3cvrA:
18.50
3ablT-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.42A 3ablG-3cvrA:
0.0
3ablN-3cvrA:
0.3
3ablO-3cvrA:
0.0		 3ablG-3cvrA:
9.07
3ablN-3cvrA:
22.78
3ablO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_B_CHDB1086_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.45A 3abmA-3cvrA:
undetectable
3abmB-3cvrA:
undetectable
3abmT-3cvrA:
undetectable		 3abmA-3cvrA:
22.78
3abmB-3cvrA:
18.50
3abmT-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.43A 3abmG-3cvrA:
0.0
3abmN-3cvrA:
0.0
3abmO-3cvrA:
0.0		 3abmG-3cvrA:
9.07
3abmN-3cvrA:
22.78
3abmO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.44A 3ag1A-3cvrA:
0.6
3ag1B-3cvrA:
undetectable
3ag1T-3cvrA:
undetectable		 3ag1A-3cvrA:
22.78
3ag1B-3cvrA:
18.50
3ag1T-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.45A 3ag1G-3cvrA:
undetectable
3ag1N-3cvrA:
1.5
3ag1O-3cvrA:
undetectable		 3ag1G-3cvrA:
9.07
3ag1N-3cvrA:
22.78
3ag1O-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_G_CHDG86_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.42A 3ag2G-3cvrA:
0.0
3ag2N-3cvrA:
0.6
3ag2O-3cvrA:
0.0		 3ag2G-3cvrA:
9.07
3ag2N-3cvrA:
22.78
3ag2O-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.39A 3ag3A-3cvrA:
undetectable
3ag3B-3cvrA:
undetectable
3ag3T-3cvrA:
undetectable		 3ag3A-3cvrA:
22.78
3ag3B-3cvrA:
18.50
3ag3T-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.42A 3ag3G-3cvrA:
undetectable
3ag3N-3cvrA:
undetectable
3ag3O-3cvrA:
undetectable		 3ag3G-3cvrA:
9.07
3ag3N-3cvrA:
22.78
3ag3O-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 12 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.41A 3ag4A-3cvrA:
undetectable
3ag4B-3cvrA:
undetectable
3ag4T-3cvrA:
undetectable		 3ag4A-3cvrA:
22.78
3ag4B-3cvrA:
18.50
3ag4T-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.43A 3ag4G-3cvrA:
0.0
3ag4N-3cvrA:
2.0
3ag4O-3cvrA:
0.0		 3ag4G-3cvrA:
9.07
3ag4N-3cvrA:
22.78
3ag4O-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.42A 3asnA-3cvrA:
undetectable
3asnB-3cvrA:
undetectable
3asnT-3cvrA:
undetectable		 3asnA-3cvrA:
22.78
3asnB-3cvrA:
18.50
3asnT-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_G_CHDG229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.42A 3asnG-3cvrA:
0.0
3asnN-3cvrA:
0.0
3asnO-3cvrA:
0.0		 3asnG-3cvrA:
9.07
3asnN-3cvrA:
22.78
3asnO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.42A 3asoA-3cvrA:
undetectable
3asoB-3cvrA:
undetectable
3asoT-3cvrA:
undetectable		 3asoA-3cvrA:
22.78
3asoB-3cvrA:
18.50
3asoT-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_G_CHDG229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.41A 3asoG-3cvrA:
0.0
3asoN-3cvrA:
0.2
3asoO-3cvrA:
0.0		 3asoG-3cvrA:
9.07
3asoN-3cvrA:
22.78
3asoO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		3 / 3 VAL A 445
SER A 329
LEU A 429
 None
 0.69A 3n8xA-3cvrA:
0.8		 3n8xA-3cvrA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.42A 3wg7A-3cvrA:
0.8
3wg7B-3cvrA:
undetectable
3wg7T-3cvrA:
undetectable		 3wg7A-3cvrA:
22.78
3wg7B-3cvrA:
18.50
3wg7T-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.41A 3wg7G-3cvrA:
0.0
3wg7N-3cvrA:
0.0
3wg7O-3cvrA:
0.0		 3wg7G-3cvrA:
9.07
3wg7N-3cvrA:
22.78
3wg7O-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.43A 3x2qA-3cvrA:
2.3
3x2qB-3cvrA:
undetectable
3x2qT-3cvrA:
undetectable		 3x2qA-3cvrA:
22.78
3x2qB-3cvrA:
18.50
3x2qT-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_O_CHDO302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.41A 3x2qG-3cvrA:
0.0
3x2qN-3cvrA:
0.0
3x2qO-3cvrA:
0.0		 3x2qG-3cvrA:
9.07
3x2qN-3cvrA:
22.78
3x2qO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_C_QMRC1214_1
(CAPITELLA TELETA
ACHBP)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		4 / 8 VAL A 198
CYH A 214
ILE A 210
ILE A 235
 None
 0.84A 4afgD-3cvrA:
undetectable
4afgE-3cvrA:
undetectable		 4afgD-3cvrA:
16.43
4afgE-3cvrA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_A_ACTA1002_0
(ACTIN, ALPHA
SKELETAL MUSCLE
FORMIN-LIKE PROTEIN
3)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		4 / 5 ARG A  68
GLN A  65
GLU A  86
THR A  88
 None
 1.28A 4eahA-3cvrA:
2.3
4eahE-3cvrA:
2.3
4eahG-3cvrA:
0.0		 4eahA-3cvrA:
24.35
4eahE-3cvrA:
24.35
4eahG-3cvrA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_C_ACTC1002_0
(ACTIN, ALPHA
SKELETAL MUSCLE
FORMIN-LIKE PROTEIN
3)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		4 / 4 ARG A  68
GLN A  65
GLU A  86
THR A  88
 None
 1.34A 4eahC-3cvrA:
2.3
4eahH-3cvrA:
0.0		 4eahC-3cvrA:
24.35
4eahH-3cvrA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		4 / 4 LEU A 138
PRO A 139
LEU A 142
ILE A 145
 None
 0.89A 4f4dB-3cvrA:
undetectable		 4f4dB-3cvrA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		4 / 7 VAL A  84
ILE A  82
LEU A  71
LEU A  74
 None
 0.96A 4xo7A-3cvrA:
undetectable		 4xo7A-3cvrA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.42A 5b1aA-3cvrA:
0.0
5b1aB-3cvrA:
undetectable
5b1aT-3cvrA:
undetectable		 5b1aA-3cvrA:
22.78
5b1aB-3cvrA:
18.50
5b1aT-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_O_CHDO302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.45A 5b1aG-3cvrA:
0.0
5b1aN-3cvrA:
0.0
5b1aO-3cvrA:
0.0		 5b1aG-3cvrA:
9.07
5b1aN-3cvrA:
22.78
5b1aO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.44A 5b1bA-3cvrA:
0.0
5b1bB-3cvrA:
0.0
5b1bT-3cvrA:
0.0		 5b1bA-3cvrA:
22.78
5b1bB-3cvrA:
18.50
5b1bT-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.43A 5b1bG-3cvrA:
undetectable
5b1bN-3cvrA:
1.4
5b1bO-3cvrA:
undetectable		 5b1bG-3cvrA:
9.07
5b1bN-3cvrA:
22.78
5b1bO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.41A 5b3sA-3cvrA:
0.0
5b3sB-3cvrA:
0.0
5b3sT-3cvrA:
0.0		 5b3sA-3cvrA:
22.78
5b3sB-3cvrA:
18.50
5b3sT-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_G_CHDG102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.42A 5b3sG-3cvrA:
0.0
5b3sN-3cvrA:
0.2
5b3sO-3cvrA:
0.0		 5b3sG-3cvrA:
9.07
5b3sN-3cvrA:
22.78
5b3sO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 12 PRO A  99
LEU A  71
ASN A  77
LEU A  64
CYH A  56
 None
 1.27A 5emlA-3cvrA:
undetectable		 5emlA-3cvrA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		3 / 3 PRO A 179
ILE A 236
SER A 161
 None
 0.72A 5fsaA-3cvrA:
0.3		 5fsaA-3cvrA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		4 / 6 PHE A 431
SER A 324
VAL A 323
ASP A 423
 None
 1.24A 5hesA-3cvrA:
undetectable		 5hesA-3cvrA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_G_CHDG102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.43A 5iy5G-3cvrA:
0.0
5iy5N-3cvrA:
0.7
5iy5O-3cvrA:
0.0		 5iy5G-3cvrA:
9.58
5iy5N-3cvrA:
22.78
5iy5O-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_T_CHDT103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.41A 5iy5A-3cvrA:
2.1
5iy5B-3cvrA:
0.0
5iy5T-3cvrA:
0.0		 5iy5A-3cvrA:
22.78
5iy5B-3cvrA:
18.50
5iy5T-3cvrA:
9.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		4 / 7 VAL A 127
LEU A 132
ALA A 107
LEU A 122
 None
 0.65A 5jq7A-3cvrA:
undetectable		 5jq7A-3cvrA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		3 / 3 ASP A 128
ASN A 146
ASP A 186
 None
 0.70A 5vopA-3cvrA:
undetectable		 5vopA-3cvrA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		3 / 3 ASP A 128
ASN A 146
ASP A 186
 None
 0.78A 5vopB-3cvrA:
undetectable		 5vopB-3cvrA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.46A 5w97G-3cvrA:
undetectable
5w97a-3cvrA:
0.2
5w97b-3cvrA:
undetectable		 5w97G-3cvrA:
9.07
5w97a-3cvrA:
22.78
5w97b-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.46A 5w97A-3cvrA:
0.0
5w97B-3cvrA:
0.0
5w97g-3cvrA:
0.0		 5w97A-3cvrA:
22.78
5w97B-3cvrA:
18.50
5w97g-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.42A 5wauA-3cvrA:
0.0
5wauB-3cvrA:
0.0
5waug-3cvrA:
0.0		 5wauA-3cvrA:
22.78
5wauB-3cvrA:
18.50
5waug-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.44A 5wauG-3cvrA:
0.0
5waua-3cvrA:
0.7
5waub-3cvrA:
0.0		 5wauG-3cvrA:
9.07
5waua-3cvrA:
22.78
5waub-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.41A 5x19A-3cvrA:
0.0
5x19B-3cvrA:
0.0
5x19T-3cvrA:
0.0		 5x19A-3cvrA:
22.78
5x19B-3cvrA:
18.50
5x19T-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_G_CHDG104_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.44A 5x19G-3cvrA:
0.0
5x19N-3cvrA:
0.0
5x19O-3cvrA:
0.0		 5x19G-3cvrA:
9.07
5x19N-3cvrA:
22.78
5x19O-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.42A 5x1bA-3cvrA:
1.5
5x1bB-3cvrA:
0.0
5x1bT-3cvrA:
0.0		 5x1bA-3cvrA:
22.78
5x1bB-3cvrA:
18.50
5x1bT-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_O_CHDO302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.41A 5x1bG-3cvrA:
0.0
5x1bN-3cvrA:
0.4
5x1bO-3cvrA:
0.0		 5x1bG-3cvrA:
9.07
5x1bN-3cvrA:
22.78
5x1bO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.44A 5x1fA-3cvrA:
0.3
5x1fB-3cvrA:
0.0
5x1fT-3cvrA:
0.0		 5x1fA-3cvrA:
22.78
5x1fB-3cvrA:
18.50
5x1fT-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_G_CHDG104_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.41A 5x1fG-3cvrA:
0.0
5x1fN-3cvrA:
0.3
5x1fO-3cvrA:
0.0		 5x1fG-3cvrA:
9.07
5x1fN-3cvrA:
22.78
5x1fO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.43A 5xdqA-3cvrA:
0.1
5xdqB-3cvrA:
undetectable
5xdqT-3cvrA:
undetectable		 5xdqA-3cvrA:
22.78
5xdqB-3cvrA:
18.50
5xdqT-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_G_CHDG102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.43A 5xdqG-3cvrA:
0.0
5xdqN-3cvrA:
0.0
5xdqO-3cvrA:
0.0		 5xdqG-3cvrA:
9.07
5xdqN-3cvrA:
22.78
5xdqO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.44A 5xdxA-3cvrA:
0.5
5xdxB-3cvrA:
undetectable
5xdxT-3cvrA:
undetectable		 5xdxA-3cvrA:
22.78
5xdxB-3cvrA:
18.50
5xdxT-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_O_CHDO301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.43A 5xdxG-3cvrA:
0.0
5xdxN-3cvrA:
0.6
5xdxO-3cvrA:
0.0		 5xdxG-3cvrA:
9.07
5xdxN-3cvrA:
22.78
5xdxO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.41A 5z84A-3cvrA:
0.0
5z84B-3cvrA:
0.0
5z84T-3cvrA:
0.0		 5z84A-3cvrA:
22.78
5z84B-3cvrA:
18.50
5z84T-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_G_CHDG101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.42A 5z84G-3cvrA:
0.0
5z84N-3cvrA:
0.0
5z84O-3cvrA:
0.0		 5z84G-3cvrA:
9.07
5z84N-3cvrA:
22.78
5z84O-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.41A 5z85G-3cvrA:
0.0
5z85N-3cvrA:
0.7
5z85O-3cvrA:
0.0		 5z85G-3cvrA:
9.07
5z85N-3cvrA:
22.78
5z85O-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_T_CHDT101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.39A 5z85A-3cvrA:
1.7
5z85B-3cvrA:
0.0
5z85T-3cvrA:
0.0		 5z85A-3cvrA:
22.78
5z85B-3cvrA:
18.50
5z85T-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.42A 5z86A-3cvrA:
0.4
5z86B-3cvrA:
undetectable
5z86T-3cvrA:
undetectable		 5z86A-3cvrA:
22.78
5z86B-3cvrA:
18.50
5z86T-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.42A 5z86G-3cvrA:
0.0
5z86N-3cvrA:
0.0
5z86O-3cvrA:
0.0		 5z86G-3cvrA:
9.07
5z86N-3cvrA:
22.78
5z86O-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.42A 5zcoA-3cvrA:
0.0
5zcoB-3cvrA:
0.0
5zcoT-3cvrA:
0.0		 5zcoA-3cvrA:
22.78
5zcoB-3cvrA:
18.50
5zcoT-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_G_CHDG102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.41A 5zcoG-3cvrA:
0.0
5zcoN-3cvrA:
0.6
5zcoO-3cvrA:
0.0		 5zcoG-3cvrA:
9.07
5zcoN-3cvrA:
22.78
5zcoO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.42A 5zcpA-3cvrA:
0.0
5zcpB-3cvrA:
0.0
5zcpT-3cvrA:
0.0		 5zcpA-3cvrA:
22.78
5zcpB-3cvrA:
18.50
5zcpT-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_G_CHDG102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.40A 5zcpG-3cvrA:
0.0
5zcpN-3cvrA:
0.7
5zcpO-3cvrA:
0.0		 5zcpG-3cvrA:
9.07
5zcpN-3cvrA:
22.78
5zcpO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.41A 5zcqA-3cvrA:
0.0
5zcqB-3cvrA:
0.0
5zcqT-3cvrA:
0.0		 5zcqA-3cvrA:
22.78
5zcqB-3cvrA:
18.50
5zcqT-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.40A 5zcqG-3cvrA:
0.0
5zcqN-3cvrA:
0.4
5zcqO-3cvrA:
0.0		 5zcqG-3cvrA:
9.07
5zcqN-3cvrA:
22.78
5zcqO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 VAL A 127
LEU A 132
LEU A 152
LEU A 118
LEU A 115
 None
 0.82A 6f5uA-3cvrA:
undetectable
6f5uB-3cvrA:
undetectable		 6f5uA-3cvrA:
8.95
6f5uB-3cvrA:
8.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 VAL A 167
LEU A 172
LEU A 192
LEU A 158
LEU A 155
 None
 0.94A 6f5uA-3cvrA:
undetectable
6f5uB-3cvrA:
undetectable		 6f5uA-3cvrA:
8.95
6f5uB-3cvrA:
8.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 12 LEU A  53
GLU A  44
LEU A  92
LEU A  64
LEU A  78
 None
 1.09A 6f6iA-3cvrA:
undetectable
6f6iB-3cvrA:
undetectable		 6f6iA-3cvrA:
8.95
6f6iB-3cvrA:
8.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		4 / 7 LEU A 115
LEU A 105
LEU A 102
LEU A  74
 None
 0.61A 6g9bA-3cvrA:
undetectable
6g9bB-3cvrA:
undetectable		 6g9bA-3cvrA:
8.95
6g9bB-3cvrA:
8.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 11 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.43A 6nknA-3cvrA:
1.4
6nknB-3cvrA:
undetectable
6nknT-3cvrA:
undetectable		 6nknA-3cvrA:
22.78
6nknB-3cvrA:
18.50
6nknT-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_G_CHDG104_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 9 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.43A 6nknG-3cvrA:
0.0
6nknN-3cvrA:
1.4
6nknO-3cvrA:
0.0		 6nknG-3cvrA:
9.07
6nknN-3cvrA:
22.78
6nknO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_G_CHDG104_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.43A 6nmfG-3cvrA:
0.0
6nmfN-3cvrA:
0.8
6nmfO-3cvrA:
0.0		 6nmfG-3cvrA:
9.07
6nmfN-3cvrA:
22.78
6nmfO-3cvrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 9 MET A 402
GLY A 399
THR A 392
ARG A 375
GLY A 484
 None
 1.45A 6nmpA-3cvrA:
0.0
6nmpB-3cvrA:
0.0
6nmpT-3cvrA:
0.0		 6nmpA-3cvrA:
22.78
6nmpB-3cvrA:
18.50
6nmpT-3cvrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_O_CHDO302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3cvr INVASION PLASMID
ANTIGEN
(Shigella
flexneri) 		5 / 10 ARG A 375
GLY A 484
MET A 402
GLY A 399
THR A 392
 None
 1.45A 6nmpG-3cvrA:
0.0
6nmpN-3cvrA:
1.7
6nmpO-3cvrA:
0.0		 6nmpG-3cvrA:
9.07
6nmpN-3cvrA:
22.78
6nmpO-3cvrA:
18.50