SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cwv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		5 / 10 VAL A 124
TYR A 111
LEU A  37
LEU A 101
VAL A  80
 None
 1.21A 1cqpA-3cwvA:
undetectable
1cqpB-3cwvA:
undetectable		 1cqpA-3cwvA:
19.77
1cqpB-3cwvA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E3V_A_DXCA801_0
(STEROID
DELTA-ISOMERASE)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		5 / 12 ASP A 169
TYR A  35
PHE A 191
VAL A  57
ALA A 171
 None
 1.49A 1e3vA-3cwvA:
undetectable		 1e3vA-3cwvA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_2
(ESTROGEN RECEPTOR)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		4 / 6 LEU A 299
ASP A 247
LEU A 279
HIS A 346
 None
 1.16A 1errB-3cwvA:
undetectable		 1errB-3cwvA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_C_AG2C7004_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		4 / 6 ALA A 274
LEU A 342
LEU A 242
LEU A 352
 None
 0.91A 1mt1D-3cwvA:
undetectable
1mt1E-3cwvA:
undetectable		 1mt1D-3cwvA:
14.84
1mt1E-3cwvA:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		5 / 12 LEU A  65
LEU A  55
VAL A 189
GLU A 179
ARG A 176
 None
 0.90A 2bxfA-3cwvA:
undetectable		 2bxfA-3cwvA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		4 / 5 LEU A 299
ASP A 247
LEU A 279
HIS A 346
 None
 1.12A 2jfaA-3cwvA:
undetectable		 2jfaA-3cwvA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		3 / 3 GLY A 129
ARG A  15
TYR A 111
 None
 0.83A 2opxA-3cwvA:
undetectable		 2opxA-3cwvA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_2
(ESTROGEN RECEPTOR)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		4 / 5 LEU A 299
ASP A 247
LEU A 279
HIS A 346
 None
 1.09A 2qxsA-3cwvA:
undetectable		 2qxsA-3cwvA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_2
(ESTROGEN RECEPTOR)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		4 / 5 LEU A 299
ASP A 247
LEU A 279
HIS A 346
 None
 1.11A 2qxsB-3cwvA:
undetectable		 2qxsB-3cwvA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_B_FOLB1188_0
(DIHYDROFOLATE
REDUCTASE)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		5 / 12 LEU A 242
PHE A 339
GLN A 336
ARG A 287
THR A 349
 None
 1.26A 2w3mB-3cwvA:
undetectable		 2w3mB-3cwvA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_2
(PTERIDINE REDUCTASE)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		3 / 3 MET A 100
VAL A 113
GLU A  44
 None
 0.91A 2x9gA-3cwvA:
undetectable		 2x9gA-3cwvA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		4 / 8 ARG A 170
SER A  62
ILE A  63
ASP A  60
 None
 1.03A 2xadA-3cwvA:
undetectable		 2xadA-3cwvA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		4 / 8 ARG A 170
SER A  62
ILE A  63
ASP A  60
 None
 1.08A 2xadB-3cwvA:
undetectable		 2xadB-3cwvA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		4 / 8 ARG A 170
SER A  62
ILE A  63
ASP A  60
 None
 1.04A 2xadC-3cwvA:
undetectable		 2xadC-3cwvA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		4 / 8 ARG A 170
SER A  62
ILE A  63
ASP A  60
 None
 1.07A 2xadD-3cwvA:
undetectable		 2xadD-3cwvA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		3 / 3 ARG A 120
ILE A 115
TRP A 122
 None
 1.08A 3e7iB-3cwvA:
undetectable		 3e7iB-3cwvA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		4 / 4 LEU A  33
ALA A 106
VAL A  14
PRO A  18
 None
 1.00A 3gv1B-3cwvA:
undetectable		 3gv1B-3cwvA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		3 / 3 LEU A  65
LEU A  55
ARG A 176
 None
 0.65A 3hcnB-3cwvA:
undetectable		 3hcnB-3cwvA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		5 / 12 VAL A 271
LEU A 183
ARG A 260
GLY A 265
LEU A 322
 None
 1.26A 3j6pB-3cwvA:
undetectable		 3j6pB-3cwvA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_C_VIAC901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		4 / 7 HIS A 223
LEU A 282
PHE A 339
VAL A 271
 None
 1.01A 3jwqC-3cwvA:
undetectable		 3jwqC-3cwvA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		4 / 7 LEU A 107
SER A 108
ILE A 162
PHE A 163
 None
 0.87A 3ln1B-3cwvA:
undetectable		 3ln1B-3cwvA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		3 / 3 ARG A 120
ILE A 115
TRP A 122
 None
 1.02A 3nw2B-3cwvA:
undetectable		 3nw2B-3cwvA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		5 / 11 ILE A 331
ILE A 324
THR A 261
VAL A 305
VAL A 303
 None
 0.97A 3tmzA-3cwvA:
undetectable		 3tmzA-3cwvA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_C_CLMC221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		5 / 11 CYH A  67
SER A 104
PHE A 156
SER A  99
VAL A  53
 None
 1.33A 3u9fA-3cwvA:
undetectable
3u9fC-3cwvA:
undetectable		 3u9fA-3cwvA:
17.98
3u9fC-3cwvA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		5 / 12 SER A 104
PHE A 156
SER A  99
VAL A  53
CYH A  67
 None
 1.38A 3u9fH-3cwvA:
undetectable
3u9fI-3cwvA:
undetectable		 3u9fH-3cwvA:
17.98
3u9fI-3cwvA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		5 / 11 VAL A 152
ALA A  74
LEU A 105
VAL A 113
THR A  73
 None
 1.37A 4eilA-3cwvA:
undetectable		 4eilA-3cwvA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_C_FOLC703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		5 / 11 VAL A 152
ALA A  74
LEU A 105
VAL A 113
THR A  73
 None
 1.36A 4eilC-3cwvA:
undetectable		 4eilC-3cwvA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		5 / 11 VAL A 152
ALA A  74
LEU A 105
VAL A 113
THR A  73
 None
 1.39A 4kyaA-3cwvA:
undetectable		 4kyaA-3cwvA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_C_FOLC703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		5 / 10 VAL A 152
ALA A  74
LEU A 105
VAL A 113
THR A  73
 None
 1.39A 4kyaC-3cwvA:
undetectable		 4kyaC-3cwvA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		5 / 11 VAL A 152
ALA A  74
LEU A 105
VAL A 113
THR A  73
 None
 1.36A 4kyaE-3cwvA:
undetectable		 4kyaE-3cwvA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_G_FOLG703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		5 / 11 VAL A 152
ALA A  74
LEU A 105
VAL A 113
THR A  73
 None
 1.38A 4kyaG-3cwvA:
undetectable		 4kyaG-3cwvA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		5 / 12 LEU A 352
VAL A 295
GLY A 277
ALA A 278
VAL A 227
 None
 1.02A 4xdrA-3cwvA:
undetectable		 4xdrA-3cwvA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		4 / 7 LEU A 343
ALA A 278
ALA A 274
LEU A 242
 None
 0.65A 4z90F-3cwvA:
undetectable
4z90G-3cwvA:
undetectable
4z90H-3cwvA:
undetectable
4z90J-3cwvA:
undetectable		 4z90F-3cwvA:
19.95
4z90G-3cwvA:
19.95
4z90H-3cwvA:
19.95
4z90J-3cwvA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED
(Myxococcus
xanthus) 		4 / 6 LEU A 107
SER A 108
ILE A 162
PHE A 163
 None
 0.96A 5jw1A-3cwvA:
undetectable		 5jw1A-3cwvA:
21.04