SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cwx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3cwx PROTEIN CAGD
(Helicobacter
pylori) 		4 / 5 SER A 111
SER A 113
VAL A  63
PHE A  60
 None
 1.26A 1oipA-3cwxA:
undetectable		 1oipA-3cwxA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FO7_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3cwx PROTEIN CAGD
(Helicobacter
pylori) 		4 / 5 HIS A  75
ASP A  72
TYR A 148
PRO A 150
 None
 1.22A 3fo7A-3cwxA:
undetectable		 3fo7A-3cwxA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3cwx PROTEIN CAGD
(Helicobacter
pylori) 		4 / 5 HIS A  75
ASP A  72
TYR A 148
PRO A 150
 None
 1.15A 3h1xA-3cwxA:
undetectable		 3h1xA-3cwxA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)		 3cwx PROTEIN CAGD
(Helicobacter
pylori) 		4 / 7 ILE A  99
LEU A 163
LEU A 137
SER A 113
 None
 0.93A 3r9vA-3cwxA:
undetectable
3r9vB-3cwxA:
undetectable		 3r9vA-3cwxA:
22.97
3r9vB-3cwxA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3cwx PROTEIN CAGD
(Helicobacter
pylori) 		5 / 12 SER A 113
ILE A  53
VAL A  63
LEU A  67
ILE A  97
 None
 1.15A 3w67D-3cwxA:
undetectable		 3w67D-3cwxA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_C_ECNC403_1
(FLAVOHEMOGLOBIN)		 3cwx PROTEIN CAGD
(Helicobacter
pylori) 		5 / 9 ILE A 166
PHE A 167
TYR A 168
LEU A 163
LEU A 122
 None
 1.21A 4g1bC-3cwxA:
undetectable		 4g1bC-3cwxA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 3cwx PROTEIN CAGD
(Helicobacter
pylori) 		5 / 12 ILE A 166
LEU A 122
LEU A 137
TYR A 138
ILE A  62
 None
 1.15A 4g1bD-3cwxA:
undetectable		 4g1bD-3cwxA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_2
(PROTEASE PR5-SQV)		 3cwx PROTEIN CAGD
(Helicobacter
pylori) 		5 / 11 LEU A 142
ASP A  72
ILE A  99
VAL A  66
ILE A  70
 None
 1.24A 5kr2B-3cwxA:
undetectable		 5kr2B-3cwxA:
20.93