SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cwz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_C_08JC602_1
(CYTOCHROME P450 3A4)
3cwz RAB6-INTERACTING
PROTEIN 1

(Mus
musculus)
4 / 7 LEU B 784
ALA B 792
ILE B 779
LEU B 897
None
0.93A 5te8C-3cwzB:
undetectable
5te8C-3cwzB:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)
3cwz RAB6-INTERACTING
PROTEIN 1

(Mus
musculus)
4 / 7 ALA B 998
GLY B1025
GLY B1027
THR B 948
None
0.80A 5ybbB-3cwzB:
undetectable
5ybbB-3cwzB:
20.89