SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cx5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA500_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 3cx5 CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		4 / 4 ALA E 196
HIS E 161
HIS E 181
PRO E 195
 None
FES  E4004 (-3.2A)
FES  E4004 ( 3.2A)
FES  E4004 ( 4.7A)
 1.36A 3mbgA-3cx5E:
undetectable		 3mbgA-3cx5E:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC900_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 3cx5 CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		4 / 4 ALA E 196
HIS E 161
HIS E 181
PRO E 195
 None
FES  E4004 (-3.2A)
FES  E4004 ( 3.2A)
FES  E4004 ( 4.7A)
 1.36A 3mbgC-3cx5E:
undetectable		 3mbgC-3cx5E:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 3cx5 CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		3 / 3 PRO E 203
TYR E 205
GLY E 215
 None
 0.75A 4g2zA-3cx5E:
undetectable		 4g2zA-3cx5E:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3cx5 CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		4 / 8 ILE E 101
LEU E 200
VAL E 147
ILE E 202
 None
 0.78A 4r38A-3cx5E:
undetectable		 4r38A-3cx5E:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)		 3cx5 CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		4 / 7 GLY E 175
GLY E 189
LEU E 137
GLU E 125
 None
 0.86A 5izfA-3cx5E:
undetectable		 5izfA-3cx5E:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 3cx5 CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		5 / 11 TYR E  57
VAL E  60
GLY E  64
SER E  68
ALA E  71
 None
 0.43A 6hu9A-3cx5E:
undetectable
6hu9E-3cx5E:
undetectable
6hu9I-3cx5E:
3.5		 6hu9A-3cx5E:
18.55
6hu9E-3cx5E:
100.00
6hu9I-3cx5E:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 3cx5 CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		5 / 10 TYR E  57
VAL E  60
GLY E  64
SER E  68
ALA E  71
 None
 0.37A 6hu9L-3cx5E:
2.3
6hu9P-3cx5E:
undetectable
6hu9T-3cx5E:
undetectable		 6hu9L-3cx5E:
18.55
6hu9P-3cx5E:
100.00
6hu9T-3cx5E:
17.65