SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cx7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEG_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 3cx7 GLUTAMATE
TRANSPORTER
ASSOCIATED PROTEIN
48
(Rattus
norvegicus) 		5 / 12 PRO B 414
LEU B 408
TYR B 366
PHE B 385
LEU B 386
 None
 1.43A 3megA-3cx7B:
undetectable		 3megA-3cx7B:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME
KP18CYS PEPTIDE)		 3cx7 GLUTAMATE
TRANSPORTER
ASSOCIATED PROTEIN
48
(Rattus
norvegicus) 		5 / 12 GLN B 367
SER B 374
LEU B 377
ILE B 381
LEU B 386
 None
 1.30A 4k38A-3cx7B:
undetectable
4k38D-3cx7B:
undetectable		 4k38A-3cx7B:
21.25
4k38D-3cx7B:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 3cx7 GLUTAMATE
TRANSPORTER
ASSOCIATED PROTEIN
48
(Rattus
norvegicus) 		4 / 7 GLU B 450
GLY B 443
TYR B 436
GLY B 445
 None
 0.73A 4rdxA-3cx7B:
undetectable		 4rdxA-3cx7B:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3cx7 GLUTAMATE
TRANSPORTER
ASSOCIATED PROTEIN
48
(Rattus
norvegicus) 		5 / 12 GLN B 470
GLU B 463
LEU B 454
LEU B 474
PHE B 328
 None
 1.30A 4retC-3cx7B:
undetectable		 4retC-3cx7B:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3cx7 GLUTAMATE
TRANSPORTER
ASSOCIATED PROTEIN
48
(Rattus
norvegicus) 		4 / 7 ILE B 396
GLN B 401
GLU B 387
VAL B 394
 None
 1.04A 6j20A-3cx7B:
undetectable		 6j20A-3cx7B:
17.51