SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cxb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 3cxb PROTEIN SIFA
(Salmonella
enterica) 		4 / 7 PHE A  84
ALA A  76
PHE A  38
PHE A  37
 None
 1.17A 1lqtA-3cxbA:
undetectable		 1lqtA-3cxbA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 3cxb PROTEIN SIFA
(Salmonella
enterica) 		4 / 7 PHE A  84
ALA A  76
PHE A  38
PHE A  37
 None
 1.18A 1lquA-3cxbA:
undetectable		 1lquA-3cxbA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3cxb PROTEIN SIFA
(Salmonella
enterica) 		4 / 7 ILE A 294
GLN A 297
VAL A 298
ILE A 181
 None
 0.87A 6cduF-3cxbA:
undetectable
6cduG-3cxbA:
undetectable		 6cduF-3cxbA:
20.89
6cduG-3cxbA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3cxb PROTEIN SIFA
(Salmonella
enterica) 		5 / 6 ASN A  88
ASP A  93
SER A 162
ARG A 150
ARG A 151
 None
 0.98A 6dwdA-3cxbA:
undetectable
6dwdC-3cxbA:
undetectable		 6dwdA-3cxbA:
21.86
6dwdC-3cxbA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3cxb PROTEIN SIFA
(Salmonella
enterica) 		4 / 5 ASN A  88
ASP A  93
ARG A 150
ARG A 151
 None
 0.94A 6dwdB-3cxbA:
undetectable
6dwdD-3cxbA:
undetectable		 6dwdB-3cxbA:
21.86
6dwdD-3cxbA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWJ_B_GLYB710_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3cxb PROTEIN SIFA
(Salmonella
enterica) 		4 / 5 ARG A 150
ARG A 151
ASN A  88
ASP A  93
 None
 1.12A 6dwjB-3cxbA:
undetectable
6dwjD-3cxbA:
undetectable		 6dwjB-3cxbA:
21.86
6dwjD-3cxbA:
21.86