SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cym'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E3V_A_DXCA801_0
(STEROID
DELTA-ISOMERASE)
3cym UNCHARACTERIZED
PROTEIN BAD_0989

(Bifidobacterium
adolescentis)
5 / 12 TYR A  28
GLY A  37
PHE A  85
VAL A  89
ALA A  41
None
1.31A 1e3vA-3cymA:
undetectable
1e3vA-3cymA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)
3cym UNCHARACTERIZED
PROTEIN BAD_0989

(Bifidobacterium
adolescentis)
4 / 6 PRO A 158
ASN A 165
ASP A 162
TRP A 163
None
1.40A 1hpkA-3cymA:
undetectable
1hpkA-3cymA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)
3cym UNCHARACTERIZED
PROTEIN BAD_0989

(Bifidobacterium
adolescentis)
3 / 3 SER A 345
ARG A 392
GLN A 389
None
0.90A 2xnrA-3cymA:
undetectable
2xnrA-3cymA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEC_A_STIA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)
3cym UNCHARACTERIZED
PROTEIN BAD_0989

(Bifidobacterium
adolescentis)
4 / 4 LEU A 143
MET A 181
ILE A  67
ASP A  63
None
0.93A 3hecA-3cymA:
undetectable
3hecA-3cymA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TX2_A_BEZA251_0
(PROBABLE
6-PHOSPHOGLUCONOLACT
ONASE)
3cym UNCHARACTERIZED
PROTEIN BAD_0989

(Bifidobacterium
adolescentis)
4 / 7 ALA A 194
TRP A 417
TRP A 193
ALA A 122
None
1.26A 3tx2A-3cymA:
undetectable
3tx2A-3cymA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)
3cym UNCHARACTERIZED
PROTEIN BAD_0989

(Bifidobacterium
adolescentis)
3 / 3 ARG A 415
ASP A  98
GLN A 101
GOL  A 503 (-3.0A)
None
None
0.92A 4azsA-3cymA:
undetectable
4azsA-3cymA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)
3cym UNCHARACTERIZED
PROTEIN BAD_0989

(Bifidobacterium
adolescentis)
3 / 3 GLN A 412
TYR A 390
ASN A 393
None
1.04A 6dwdC-3cymA:
undetectable
6dwdC-3cymA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)
3cym UNCHARACTERIZED
PROTEIN BAD_0989

(Bifidobacterium
adolescentis)
4 / 6 TRP A  94
GLY A  66
ALA A  40
LEU A  39
None
1.07A 6fosA-3cymA:
2.1
6fosA-3cymA:
11.90