SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cyq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_B_FFOB361_0
(DIHYDROFOLATE
REDUCTASE)		 3cyq CHEMOTAXIS PROTEIN
MOTB
(Helicobacter
pylori) 		5 / 12 ILE B 229
PHE B 231
ILE B 244
LEU B 151
PRO B 152
 None
 1.14A 1jolB-3cyqB:
undetectable		 1jolB-3cyqB:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_B_FFOB361_0
(DIHYDROFOLATE
REDUCTASE)		 3cyq CHEMOTAXIS PROTEIN
MOTB
(Helicobacter
pylori) 		5 / 12 ILE B 229
PHE B 231
LEU B 151
PRO B 152
TYR B 140
 None
 1.11A 1jolB-3cyqB:
undetectable		 1jolB-3cyqB:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_A_FOLA1161_0
(DIHYDROFOLATE
REDUCTASE)		 3cyq CHEMOTAXIS PROTEIN
MOTB
(Helicobacter
pylori) 		5 / 12 ILE B 229
PHE B 231
ILE B 244
LEU B 151
PRO B 152
 None
 0.95A 2d0kA-3cyqB:
undetectable		 2d0kA-3cyqB:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 3cyq CHEMOTAXIS PROTEIN
MOTB
(Helicobacter
pylori) 		4 / 4 LEU B 201
ILE B 229
ILE B 144
ALA B 145
 None
 0.77A 2i30A-3cyqB:
undetectable		 2i30A-3cyqB:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 3cyq CHEMOTAXIS PROTEIN
MOTB
(Helicobacter
pylori) 		3 / 3 LYS B 240
ARG B 154
VAL B 155
 None
 0.92A 2r2vC-3cyqB:
undetectable
2r2vD-3cyqB:
undetectable		 2r2vC-3cyqB:
20.00
2r2vD-3cyqB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3cyq CHEMOTAXIS PROTEIN
MOTB
(Helicobacter
pylori) 		5 / 10 ILE B 241
THR B 233
ASP B 237
ILE B 148
ILE B 157
 None
 1.47A 3kpbD-3cyqB:
undetectable		 3kpbD-3cyqB:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3cyq CHEMOTAXIS PROTEIN
MOTB
(Helicobacter
pylori) 		4 / 6 ASP B 237
ILE B 244
THR B 233
PHE B 231
 None
 1.09A 4acbC-3cyqB:
undetectable		 4acbC-3cyqB:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3cyq CHEMOTAXIS PROTEIN
MOTB
(Helicobacter
pylori) 		4 / 8 VAL B 187
TYR B 194
VAL B 159
ILE B 144
 None
 1.12A 4aftD-3cyqB:
undetectable
4aftE-3cyqB:
undetectable		 4aftD-3cyqB:
21.96
4aftE-3cyqB:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 3cyq CHEMOTAXIS PROTEIN
MOTB
(Helicobacter
pylori) 		3 / 3 ARG B 226
ARG B 183
ILE B 212
 None
 0.89A 4b7qA-3cyqB:
undetectable		 4b7qA-3cyqB:
14.07