SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cz5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3cz5 TWO-COMPONENT
RESPONSE REGULATOR,
LUXR FAMILY
(Aurantimonas
manganoxydans) 		4 / 7 MET A 129
ALA A  94
ARG A 141
GLU A 140
 None
 1.26A 1t9wA-3cz5A:
undetectable		 1t9wA-3cz5A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3cz5 TWO-COMPONENT
RESPONSE REGULATOR,
LUXR FAMILY
(Aurantimonas
manganoxydans) 		4 / 6 PHE A  98
VAL A 106
LEU A  83
ALA A 102
 None
 1.08A 2e1qA-3cz5A:
undetectable		 2e1qA-3cz5A:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 3cz5 TWO-COMPONENT
RESPONSE REGULATOR,
LUXR FAMILY
(Aurantimonas
manganoxydans) 		4 / 8 ALA A  94
PHE A  98
LEU A  59
ALA A 102
 None
None
PO4  A 201 (-4.4A)
None
 0.87A 3hrdA-3cz5A:
undetectable
3hrdB-3cz5A:
undetectable		 3hrdA-3cz5A:
18.56
3hrdB-3cz5A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3cz5 TWO-COMPONENT
RESPONSE REGULATOR,
LUXR FAMILY
(Aurantimonas
manganoxydans) 		5 / 12 ILE A 122
GLY A 104
VAL A 106
PHE A  85
TYR A  31
 None
 0.99A 5n0oA-3cz5A:
2.3		 5n0oA-3cz5A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3cz5 TWO-COMPONENT
RESPONSE REGULATOR,
LUXR FAMILY
(Aurantimonas
manganoxydans) 		5 / 12 ILE A 122
GLY A 104
VAL A 106
PHE A  85
VAL A  55
 None
 1.14A 5n0oA-3cz5A:
2.3		 5n0oA-3cz5A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3cz5 TWO-COMPONENT
RESPONSE REGULATOR,
LUXR FAMILY
(Aurantimonas
manganoxydans) 		5 / 12 ILE A 122
GLY A 104
VAL A 106
PHE A  85
TYR A  31
 None
 0.96A 5n0rA-3cz5A:
undetectable		 5n0rA-3cz5A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3cz5 TWO-COMPONENT
RESPONSE REGULATOR,
LUXR FAMILY
(Aurantimonas
manganoxydans) 		5 / 12 ILE A 122
GLY A 104
VAL A 106
PHE A  85
VAL A  55
 None
 1.15A 5n0rA-3cz5A:
undetectable		 5n0rA-3cz5A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3cz5 TWO-COMPONENT
RESPONSE REGULATOR,
LUXR FAMILY
(Aurantimonas
manganoxydans) 		5 / 12 ILE A 122
GLY A 104
VAL A 106
PHE A  85
TYR A  31
 None
 1.00A 5n0sA-3cz5A:
undetectable		 5n0sA-3cz5A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3cz5 TWO-COMPONENT
RESPONSE REGULATOR,
LUXR FAMILY
(Aurantimonas
manganoxydans) 		5 / 12 ILE A 122
GLY A 104
VAL A 106
PHE A  85
TYR A  31
 None
 0.91A 5n0tA-3cz5A:
3.3		 5n0tA-3cz5A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3cz5 TWO-COMPONENT
RESPONSE REGULATOR,
LUXR FAMILY
(Aurantimonas
manganoxydans) 		5 / 12 ILE A 122
GLY A 104
VAL A 106
PHE A  85
TYR A  31
 None
 0.96A 5n0wA-3cz5A:
2.5		 5n0wA-3cz5A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3cz5 TWO-COMPONENT
RESPONSE REGULATOR,
LUXR FAMILY
(Aurantimonas
manganoxydans) 		5 / 12 ILE A 122
GLY A 104
VAL A 106
PHE A  85
VAL A  55
 None
 1.13A 5n0wA-3cz5A:
2.5		 5n0wA-3cz5A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3cz5 TWO-COMPONENT
RESPONSE REGULATOR,
LUXR FAMILY
(Aurantimonas
manganoxydans) 		5 / 12 ILE A 122
GLY A 104
VAL A 106
PHE A  85
TYR A  31
 None
 0.95A 5n0wB-3cz5A:
2.6		 5n0wB-3cz5A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3cz5 TWO-COMPONENT
RESPONSE REGULATOR,
LUXR FAMILY
(Aurantimonas
manganoxydans) 		5 / 12 ILE A 122
GLY A 104
VAL A 106
PHE A  85
TYR A  31
 None
 0.97A 5n4iA-3cz5A:
2.5		 5n4iA-3cz5A:
17.32