SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cz8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_A_NIOA704_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		4 / 4 SER A 357
PHE A 374
GLU A 375
GLY A 376
 None
None
None
GOL  A 505 ( 4.1A)
 1.49A 1icvA-3cz8A:
undetectable
1icvB-3cz8A:
undetectable		 1icvA-3cz8A:
20.25
1icvB-3cz8A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		3 / 3 GLY A 139
ASP A 140
ASN A 184
 None
 0.66A 1vq1A-3cz8A:
undetectable		 1vq1A-3cz8A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		4 / 7 ASN A 335
GLY A 317
TRP A 373
SER A 357
 None
 1.10A 2o5yH-3cz8A:
undetectable
2o5yL-3cz8A:
undetectable		 2o5yH-3cz8A:
19.94
2o5yL-3cz8A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		4 / 8 ARG A 341
PRO A 358
SER A 379
VAL A 372
 None
 1.20A 2qd2A-3cz8A:
undetectable		 2qd2A-3cz8A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		4 / 8 HIS A 370
ASP A 319
SER A 331
ILE A 333
 None
 1.11A 2xadA-3cz8A:
undetectable		 2xadA-3cz8A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		4 / 8 HIS A 370
ASP A 319
SER A 331
ILE A 333
 None
 1.12A 2xadC-3cz8A:
2.3		 2xadC-3cz8A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		4 / 8 HIS A 370
ASP A 319
SER A 331
ILE A 333
 None
 1.12A 2xadD-3cz8A:
undetectable		 2xadD-3cz8A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		5 / 12 LYS A 308
VAL A 304
VAL A 266
GLY A 264
ILE A 242
 None
 1.22A 3bf1A-3cz8A:
undetectable
3bf1B-3cz8A:
undetectable		 3bf1A-3cz8A:
20.31
3bf1B-3cz8A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		5 / 9 ILE A 177
LEU A 182
PHE A 222
GLU A 212
GLY A 257
 None
None
None
GOL  A 502 (-3.4A)
None
 1.46A 3nxuB-3cz8A:
undetectable		 3nxuB-3cz8A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		4 / 6 VAL A 192
VAL A 181
ILE A 165
ARG A 227
 None
 1.11A 3pyyA-3cz8A:
undetectable		 3pyyA-3cz8A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		5 / 11 PHE A 131
ASP A 210
GLU A 212
TYR A 275
ASP A 276
 GOL  A 502 ( 4.7A)
GOL  A 502 (-3.4A)
GOL  A 502 (-3.4A)
None
None
 0.97A 3wqvA-3cz8A:
26.9		 3wqvA-3cz8A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		5 / 11 PHE A 131
ASP A 210
GLU A 212
TYR A 275
TRP A 398
 GOL  A 502 ( 4.7A)
GOL  A 502 (-3.4A)
GOL  A 502 (-3.4A)
None
None
 1.10A 3wqvA-3cz8A:
26.9		 3wqvA-3cz8A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		5 / 11 PHE A 131
ASP A 210
GLU A 212
TYR A 275
ASP A 276
 GOL  A 502 ( 4.7A)
GOL  A 502 (-3.4A)
GOL  A 502 (-3.4A)
None
None
 0.98A 3wqwA-3cz8A:
27.0		 3wqwA-3cz8A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		5 / 11 PHE A 131
ASP A 210
GLU A 212
TYR A 275
TRP A 398
 GOL  A 502 ( 4.7A)
GOL  A 502 (-3.4A)
GOL  A 502 (-3.4A)
None
None
 1.11A 3wqwA-3cz8A:
27.0		 3wqwA-3cz8A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		5 / 11 ILE A 293
ALA A 274
GLY A 312
GLY A 317
ASN A 335
 None
 1.28A 4e47A-3cz8A:
undetectable		 4e47A-3cz8A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		5 / 11 ILE A 293
ALA A 274
GLY A 312
GLY A 317
ASN A 335
 None
 1.27A 4e47B-3cz8A:
undetectable		 4e47B-3cz8A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		5 / 11 ILE A 293
ALA A 274
GLY A 312
GLY A 317
ASN A 335
 None
 1.26A 4jdsA-3cz8A:
undetectable		 4jdsA-3cz8A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		5 / 11 ILE A 293
ALA A 274
GLY A 312
GLY A 317
ASN A 335
 None
 1.27A 4jdsB-3cz8A:
undetectable		 4jdsB-3cz8A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		4 / 6 LEU A 198
TYR A 133
ILE A 151
GLY A 206
 None
 1.00A 4l39A-3cz8A:
1.9		 4l39A-3cz8A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		6 / 12 LEU A 191
LEU A 233
ILE A 209
LEU A 226
ILE A 141
PHE A 225
 None
 1.39A 4odrA-3cz8A:
undetectable
4odrB-3cz8A:
undetectable		 4odrA-3cz8A:
16.46
4odrB-3cz8A:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		6 / 12 LEU A 233
ILE A 209
LEU A 226
ILE A 141
ILE A 135
PHE A 225
 None
 1.39A 4odrA-3cz8A:
undetectable
4odrB-3cz8A:
undetectable		 4odrA-3cz8A:
16.46
4odrB-3cz8A:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		4 / 8 SER A 127
SER A 104
GLU A 212
ASP A 210
 GOL  A 501 (-2.9A)
GOL  A 506 ( 4.7A)
GOL  A 502 (-3.4A)
GOL  A 502 (-3.4A)
 1.15A 4qb9D-3cz8A:
undetectable		 4qb9D-3cz8A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		5 / 12 SER A 126
THR A 401
ALA A 397
ARG A 157
THR A 154
 None
GOL  A 506 (-3.6A)
None
GOL  A 506 ( 4.6A)
None
 1.24A 4qvnV-3cz8A:
undetectable
4qvnb-3cz8A:
undetectable		 4qvnV-3cz8A:
20.81
4qvnb-3cz8A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		5 / 12 SER A 126
THR A 401
ALA A 397
ARG A 157
THR A 154
 None
GOL  A 506 (-3.6A)
None
GOL  A 506 ( 4.6A)
None
 1.24A 4qvnH-3cz8A:
undetectable
4qvnN-3cz8A:
undetectable		 4qvnH-3cz8A:
20.81
4qvnN-3cz8A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP4_A_COCA706_1
(DOPAMINE TRANSPORTER)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		5 / 11 VAL A 372
GLY A 376
PHE A 374
SER A 334
GLY A 317
 None
GOL  A 505 ( 4.1A)
None
None
None
 1.28A 4xp4A-3cz8A:
undetectable		 4xp4A-3cz8A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XPB_A_COCA702_1
(TRANSPORTER)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		5 / 10 VAL A 372
GLY A 376
PHE A 374
SER A 334
GLY A 317
 None
GOL  A 505 ( 4.1A)
None
None
None
 1.20A 4xpbA-3cz8A:
undetectable		 4xpbA-3cz8A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		5 / 11 TYR A 133
ASP A 147
LEU A 198
VAL A 207
ALA A 150
 None
None
None
None
GOL  A 506 ( 4.0A)
 1.13A 5d75A-3cz8A:
undetectable		 5d75A-3cz8A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		5 / 12 LEU A 182
ALA A 187
LEU A 191
ASN A 194
ILE A 177
 None
 1.11A 5itzB-3cz8A:
undetectable		 5itzB-3cz8A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		4 / 8 LEU A 400
ILE A  99
ALA A 100
LEU A 402
 None
 0.76A 5te8B-3cz8A:
undetectable		 5te8B-3cz8A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCO_A_FY5A1003_0
(ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
2)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		6 / 11 PHE A 271
VAL A 107
THR A 160
THR A 164
ILE A 165
VAL A 207
 None
GOL  A 501 ( 4.2A)
GOL  A 501 (-3.8A)
None
None
None
 1.42A 6hcoA-3cz8A:
0.7
6hcoB-3cz8A:
2.1		 6hcoA-3cz8A:
19.10
6hcoB-3cz8A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J21_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD
(Bacillus
subtilis) 		5 / 12 ASN A 167
VAL A 244
ILE A 195
VAL A 267
PHE A 222
 None
 1.43A 6j21A-3cz8A:
undetectable		 6j21A-3cz8A:
19.69