SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3czb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)
3czb PUTATIVE
TRANSGLYCOSYLASE

(Caulobacter
vibrioides)
4 / 8 ARG A 276
SER A 202
TYR A 141
TYR A 290
None
SO4  A   1 (-2.3A)
None
None
1.12A 2y05A-3czbA:
undetectable
2y05B-3czbA:
undetectable
2y05A-3czbA:
20.52
2y05B-3czbA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)
3czb PUTATIVE
TRANSGLYCOSYLASE

(Caulobacter
vibrioides)
3 / 3 PHE A 245
ASN A 287
PHE A 215
None
1.09A 2zbuD-3czbA:
undetectable
2zbuD-3czbA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_1
(RENIN)
3czb PUTATIVE
TRANSGLYCOSYLASE

(Caulobacter
vibrioides)
5 / 12 GLN A 218
GLY A 305
PHE A 293
ASP A 354
ALA A 318
None
1.16A 3d91A-3czbA:
undetectable
3d91A-3czbA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)
3czb PUTATIVE
TRANSGLYCOSYLASE

(Caulobacter
vibrioides)
5 / 10 VAL A 291
PHE A 293
ILE A 219
GLY A 357
THR A 355
None
1.37A 3t3rD-3czbA:
undetectable
3t3rD-3czbA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)
3czb PUTATIVE
TRANSGLYCOSYLASE

(Caulobacter
vibrioides)
4 / 7 ASN A 287
LEU A 272
LEU A 214
ILE A 268
None
0.99A 4okwA-3czbA:
undetectable
4okwA-3czbA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)
3czb PUTATIVE
TRANSGLYCOSYLASE

(Caulobacter
vibrioides)
4 / 7 GLY A 247
MET A 252
ALA A 358
ILE A 219
None
0.94A 4txnC-3czbA:
undetectable
4txnC-3czbA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)
3czb PUTATIVE
TRANSGLYCOSYLASE

(Caulobacter
vibrioides)
4 / 5 LEU A 332
ALA A 135
VAL A 319
ILE A 359
None
0.87A 4xe3B-3czbA:
undetectable
4xe3B-3czbA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)
3czb PUTATIVE
TRANSGLYCOSYLASE

(Caulobacter
vibrioides)
3 / 3 HIS A 275
GLU A 274
TRP A 271
None
1.06A 5odiD-3czbA:
undetectable
5odiD-3czbA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)
3czb PUTATIVE
TRANSGLYCOSYLASE

(Caulobacter
vibrioides)
3 / 3 HIS A 275
GLU A 274
TRP A 271
None
1.11A 5odqD-3czbA:
undetectable
5odqD-3czbA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)
3czb PUTATIVE
TRANSGLYCOSYLASE

(Caulobacter
vibrioides)
3 / 3 HIS A 275
GLU A 274
TRP A 271
None
1.04A 5odrD-3czbA:
undetectable
5odrD-3czbA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)
3czb PUTATIVE
TRANSGLYCOSYLASE

(Caulobacter
vibrioides)
4 / 6 ASP A 333
ARG A 387
LEU A 386
ASP A 130
None
1.20A 5tdzA-3czbA:
undetectable
5tdzA-3czbA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)
3czb PUTATIVE
TRANSGLYCOSYLASE

(Caulobacter
vibrioides)
5 / 10 GLY A 223
LEU A 217
VAL A 233
ALA A 143
LEU A 155
None
1.01A 6czmA-3czbA:
undetectable
6czmC-3czbA:
undetectable
6czmA-3czbA:
22.75
6czmC-3czbA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)
3czb PUTATIVE
TRANSGLYCOSYLASE

(Caulobacter
vibrioides)
4 / 6 PHE A 216
ILE A 248
MET A 284
ASN A 287
None
1.34A 6dhbA-3czbA:
undetectable
6dhbA-3czbA:
13.64