SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3czc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 3czc RMPB
(Streptococcus
mutans) 		4 / 7 LEU A  72
ALA A  56
LYS A  45
ALA A  48
 None
 1.08A 1sn0B-3czcA:
undetectable
1sn0D-3czcA:
undetectable		 1sn0B-3czcA:
21.05
1sn0D-3czcA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 3czc RMPB
(Streptococcus
mutans) 		4 / 7 LYS A  45
ALA A  48
LEU A  72
ALA A  56
 None
 1.07A 1sn0B-3czcA:
undetectable
1sn0D-3czcA:
undetectable		 1sn0B-3czcA:
21.05
1sn0D-3czcA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 3czc RMPB
(Streptococcus
mutans) 		5 / 12 ALA A  48
GLY A  70
GLU A  83
ILE A  84
LEU A  78
 None
 1.10A 2plwA-3czcA:
undetectable		 2plwA-3czcA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 3czc RMPB
(Streptococcus
mutans) 		5 / 12 GLY A  74
ASN A  58
HIS A  59
ILE A  53
SER A  36
 None
 1.21A 4pooA-3czcA:
undetectable		 4pooA-3czcA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 3czc RMPB
(Streptococcus
mutans) 		5 / 12 GLY A  74
ASN A  58
HIS A  59
ILE A  53
SER A  36
 None
 1.36A 4pooB-3czcA:
undetectable		 4pooB-3czcA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 3czc RMPB
(Streptococcus
mutans) 		4 / 7 VAL A  55
ILE A  53
VAL A  22
ILE A  18
 None
 0.80A 5bmvC-3czcA:
undetectable		 5bmvC-3czcA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 3czc RMPB
(Streptococcus
mutans) 		3 / 3 ASP A  80
ASN A  24
GLN A  28
 None
 0.81A 5k7uA-3czcA:
undetectable		 5k7uA-3czcA:
18.10