SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cze'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA495_1
(GLUCOAMYLASE-471)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 12 TYR A 114
TRP A 524
GLY A 103
TYR A  94
GLU A 495
 None
 1.29A 1agmA-3czeA:
undetectable		 1agmA-3czeA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA496_1
(GLUCOAMYLASE-471)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 12 TYR A 114
TRP A 524
GLY A 103
TYR A  94
GLU A 495
 None
 1.29A 1agmA-3czeA:
undetectable		 1agmA-3czeA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 10 VAL A 120
TYR A  94
LEU A 126
LEU A 125
VAL A 108
 None
 1.16A 1cqpA-3czeA:
undetectable
1cqpB-3czeA:
undetectable		 1cqpA-3czeA:
14.96
1cqpB-3czeA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 7 VAL A 108
VAL A 120
TYR A  94
LEU A 126
LEU A 125
 None
 1.11A 1cqpA-3czeA:
undetectable
1cqpB-3czeA:
undetectable		 1cqpA-3czeA:
14.96
1cqpB-3czeA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_1
(GLUCOAMYLASE-471)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 12 TYR A 114
TRP A 524
GLY A 103
TYR A  94
GLU A 495
 None
 1.31A 1gahA-3czeA:
undetectable		 1gahA-3czeA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		3 / 3 ALA A 263
VAL A 258
TRP A  55
 None
 0.96A 1grmA-3czeA:
undetectable		 1grmA-3czeA:
2.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		3 / 3 ALA A 263
VAL A 258
TRP A  55
 None
 0.96A 1grmB-3czeA:
undetectable		 1grmB-3czeA:
2.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 11 LEU A 272
LEU A 105
ALA A  96
ALA A  98
LEU A 129
 None
 1.31A 1iiuA-3czeA:
undetectable		 1iiuA-3czeA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		6 / 12 VAL A 475
ALA A 458
LEU A 467
ALA A 497
VAL A 499
ALA A 451
 None
 1.34A 1sa1A-3czeA:
undetectable
1sa1B-3czeA:
undetectable		 1sa1A-3czeA:
20.83
1sa1B-3czeA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		6 / 12 VAL A 475
ALA A 458
LEU A 467
ALA A 497
VAL A 499
ALA A 451
 None
 1.36A 1sa1C-3czeA:
undetectable
1sa1D-3czeA:
undetectable		 1sa1C-3czeA:
20.83
1sa1D-3czeA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		3 / 3 GLU A 167
GLU A 275
LEU A 158
 None
 0.62A 1v8bA-3czeA:
2.6		 1v8bA-3czeA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 4 HIS A  34
ASP A  78
ASN A 271
ASP A 311
 None
 1.38A 1wg8A-3czeA:
undetectable		 1wg8A-3czeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_B_SAMB302_0
(RRNA
METHYLTRANSFERASE)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 10 ASP A 570
GLY A 365
ILE A 600
LEU A 585
ALA A 575
 None
 1.12A 1x7pA-3czeA:
2.3
1x7pB-3czeA:
2.2		 1x7pA-3czeA:
18.83
1x7pB-3czeA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 6 LEU A 452
GLY A 447
HIS A 518
ASN A 446
ILE A 394
 None
 1.35A 1xf1B-3czeA:
undetectable		 1xf1B-3czeA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		3 / 3 ALA A 321
THR A 282
PHE A 334
 None
 0.71A 2c6nB-3czeA:
undetectable		 2c6nB-3czeA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 12 LEU A 105
VAL A 108
VAL A 112
ILE A 170
ALA A 174
 None
 0.94A 2gj5A-3czeA:
undetectable		 2gj5A-3czeA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J1G_F_SC2F1290_1
(FICOLIN-2)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 10 LEU A 178
SER A 281
LEU A 285
THR A 243
LYS A 287
 None
 1.30A 2j1gE-3czeA:
0.0
2j1gF-3czeA:
undetectable		 2j1gE-3czeA:
15.23
2j1gF-3czeA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 10 PHE A 277
ARG A 268
ALA A 265
LEU A 269
ALA A 270
 None
 1.49A 2wscB-3czeA:
0.7		 2wscB-3czeA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_B_PQNB1774_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 10 PHE A 277
ARG A 268
ALA A 265
LEU A 269
ALA A 270
 None
 1.49A 2wseB-3czeA:
0.6		 2wseB-3czeA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 12 VAL A 425
PHE A 420
SER A 358
GLY A 432
ALA A 430
 None
 1.24A 2x2iA-3czeA:
12.5		 2x2iA-3czeA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 10 VAL A 425
PHE A 420
SER A 358
GLY A 432
ALA A 430
 None
 1.28A 2x2iB-3czeA:
11.1		 2x2iB-3czeA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 12 VAL A 425
PHE A 420
SER A 358
GLY A 432
ALA A 430
 None
 1.23A 2x2iC-3czeA:
3.5		 2x2iC-3czeA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 12 LEU A 477
GLY A 356
LEU A 352
LEU A 360
HIS A 586
 None
 1.05A 3e23A-3czeA:
undetectable		 3e23A-3czeA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 8 ASP A 250
HIS A 300
LEU A 218
CYH A 293
 None
 0.84A 3lm8B-3czeA:
2.1
3lm8D-3czeA:
2.2		 3lm8B-3czeA:
15.10
3lm8D-3czeA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		3 / 3 GLU A 513
GLU A 433
ASN A 446
 None
 0.89A 3lp9B-3czeA:
1.2
3lp9D-3czeA:
1.2		 3lp9B-3czeA:
15.89
3lp9D-3czeA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 8 PRO A   9
SER A  36
LEU A  39
ASP A  40
 None
 0.99A 3lsfH-3czeA:
undetectable		 3lsfH-3czeA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 12 PHE A 277
LEU A  74
ALA A  67
ILE A 312
ALA A 308
 None
 1.19A 3nxuB-3czeA:
undetectable		 3nxuB-3czeA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 8 HIS A  34
ILE A 312
TRP A  59
ARG A  37
 None
 1.11A 3sfeB-3czeA:
undetectable
3sfeC-3czeA:
undetectable		 3sfeB-3czeA:
15.43
3sfeC-3czeA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		3 / 3 ARG A 545
ARG A 530
ILE A 548
 None
 0.85A 4b7qA-3czeA:
undetectable		 4b7qA-3czeA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 5 ARG A 364
VAL A 417
LEU A 414
SER A 413
 None
 0.99A 4e1gA-3czeA:
undetectable		 4e1gA-3czeA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		3 / 3 ARG A 389
TRP A 396
GLY A 395
 None
 0.99A 4e7cA-3czeA:
undetectable		 4e7cA-3czeA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 5 TYR A  94
LEU A 118
TYR A 541
LEU A 496
 None
 1.37A 4em2A-3czeA:
undetectable		 4em2A-3czeA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 7 TYR A  31
LEU A  38
TRP A  59
TYR A  52
 None
 1.22A 4f8yC-3czeA:
undetectable
4f8yD-3czeA:
undetectable		 4f8yC-3czeA:
13.76
4f8yD-3czeA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		3 / 3 TYR A 284
GLN A 248
TRP A 253
 None
 1.14A 4kn2C-3czeA:
undetectable		 4kn2C-3czeA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 6 VAL A  63
VAL A 313
ILE A 312
LEU A  39
 None
 0.93A 4l1wB-3czeA:
7.4		 4l1wB-3czeA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 5 GLY A  61
LEU A  27
LEU A 267
LEU A  39
 None
 0.85A 4o8fA-3czeA:
undetectable		 4o8fA-3czeA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 12 SER A 336
THR A 282
ALA A 283
ALA A 299
ASN A 295
 None
 1.31A 4u15A-3czeA:
undetectable		 4u15A-3czeA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 7 ARG A 197
ARG A  49
ASP A  51
TYR A 201
 None
 1.50A 5a06A-3czeA:
undetectable		 5a06A-3czeA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 7 ARG A 197
ARG A  49
ASP A  51
TYR A 201
 None
 1.49A 5a06C-3czeA:
2.2		 5a06C-3czeA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 7 ARG A 197
ARG A  49
ASP A  51
TYR A 201
 None
 1.49A 5a06D-3czeA:
undetectable		 5a06D-3czeA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 7 ARG A 197
ARG A  49
ASP A  51
TYR A 201
 None
 1.49A 5a06E-3czeA:
undetectable		 5a06E-3czeA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 7 ARG A 197
ARG A  49
ASP A  51
TYR A 201
 None
 1.49A 5a06F-3czeA:
undetectable		 5a06F-3czeA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 7 ALA A 451
ASP A 393
ARG A 515
GLY A 514
GLU A 513
 None
None
TRS  A6646 (-2.8A)
None
None
 1.41A 5btgA-3czeA:
undetectable
5btgC-3czeA:
undetectable
5btgD-3czeA:
2.1		 5btgA-3czeA:
24.23
5btgC-3czeA:
24.23
5btgD-3czeA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 8 LEU A 477
GLY A 356
ALA A 355
SER A 358
 None
 0.77A 5f1aA-3czeA:
undetectable		 5f1aA-3czeA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 7 LEU A 477
GLY A 356
ALA A 355
SER A 358
 None
 0.79A 5f1aB-3czeA:
0.4		 5f1aB-3czeA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 6 ARG A 100
ASP A 507
GLY A 503
ASP A 501
 None
 1.13A 5hp1A-3czeA:
undetectable		 5hp1A-3czeA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 10 VAL A  63
GLU A  62
ALA A 263
PHE A 259
THR A 301
 None
 1.44A 5mm4B-3czeA:
undetectable		 5mm4B-3czeA:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 5 LEU A 477
LEU A 476
MET A 484
TYR A 387
 None
 1.35A 5uc3A-3czeA:
undetectable		 5uc3A-3czeA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 12 PHE A 277
LEU A  74
ALA A  67
ILE A 312
ALA A 308
 None
 1.17A 5vc0A-3czeA:
undetectable		 5vc0A-3czeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 8 VAL A 388
PRO A 488
GLY A  93
LEU A  92
 None
 0.82A 5w3jB-3czeA:
undetectable		 5w3jB-3czeA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 7 ASN A 446
HIS A 518
ASP A 137
GLY A 138
 None
None
TRS  A6646 (-3.0A)
TRS  A6646 ( 4.8A)
 1.12A 5x7pA-3czeA:
undetectable		 5x7pA-3czeA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		3 / 3 ASP A 392
PHE A 140
ARG A 278
 TRS  A6646 (-2.6A)
TRS  A6646 (-3.5A)
TRS  A6646 ( 4.0A)
 1.15A 5yw0A-3czeA:
undetectable		 5yw0A-3czeA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 6 PHE A 128
ARG A 130
LEU A 129
ALA A 174
 None
 0.99A 6b89B-3czeA:
1.5		 6b89B-3czeA:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_A_ADNA502_1
(-)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 12 HIS A 391
GLU A 322
HIS A 124
LEU A 126
GLY A 138
 TRS  A6646 (-4.0A)
None
None
None
TRS  A6646 ( 4.8A)
 1.32A 6f3mA-3czeA:
undetectable		 6f3mA-3czeA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_1
(-)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 12 HIS A 391
GLU A 322
HIS A 124
LEU A 126
GLY A 138
 TRS  A6646 (-4.0A)
None
None
None
TRS  A6646 ( 4.8A)
 1.33A 6f3mC-3czeA:
undetectable		 6f3mC-3czeA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 5 ARG A 192
ALA A 191
TYR A 202
GLN A 189
 None
 1.30A 6f6sA-3czeA:
undetectable
6f6sB-3czeA:
undetectable		 6f6sA-3czeA:
9.26
6f6sB-3czeA:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_1
(GLUCOAMYLASE P)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 12 ALA A 527
TYR A 114
TRP A 524
GLY A 103
TYR A  94
 None
 1.49A 6fhwA-3czeA:
undetectable		 6fhwA-3czeA:
9.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_B_ACRB801_1
(GLUCOAMYLASE P)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		5 / 12 ALA A 527
TYR A 114
TRP A 524
GLY A 103
TYR A  94
 None
 1.49A 6fhwB-3czeA:
undetectable		 6fhwB-3czeA:
9.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 6 SER A 413
ALA A 418
THR A 445
ALA A 354
 None
 1.09A 6ma6A-3czeA:
undetectable		 6ma6A-3czeA:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3cze SUCROSE HYDROLASE
(Xanthomonas
citri) 		4 / 7 TRP A  85
ARG A  30
HIS A  34
ASP A  78
 None
 1.36A 6mn4E-3czeA:
undetectable		 6mn4E-3czeA:
19.75