SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3czq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 3czq PUTATIVE
POLYPHOSPHATE KINASE
2
(Sinorhizobium
meliloti) 		5 / 8 PHE A 191
PHE A 193
HIS A 269
LEU A 271
VAL A  74
 None
 1.22A 1fslA-3czqA:
undetectable		 1fslA-3czqA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_1
(HIV-II PROTEASE)		 3czq PUTATIVE
POLYPHOSPHATE KINASE
2
(Sinorhizobium
meliloti) 		5 / 12 GLY A  99
ALA A 100
ILE A 254
ILE A 197
ILE A 195
 GOL  A 303 (-4.3A)
None
None
None
None
 0.77A 1hshA-3czqA:
undetectable		 1hshA-3czqA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_1
(HIV-II PROTEASE)		 3czq PUTATIVE
POLYPHOSPHATE KINASE
2
(Sinorhizobium
meliloti) 		5 / 12 GLY A  99
ALA A 100
ILE A 254
ILE A 197
ILE A 195
 GOL  A 303 (-4.3A)
None
None
None
None
 0.88A 1hshC-3czqA:
undetectable		 1hshC-3czqA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 3czq PUTATIVE
POLYPHOSPHATE KINASE
2
(Sinorhizobium
meliloti) 		4 / 5 ASP A 238
LEU A 241
LYS A 242
ARG A 237
 None
 1.38A 2gj5A-3czqA:
undetectable		 2gj5A-3czqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_2
(ADENOSINE KINASE)		 3czq PUTATIVE
POLYPHOSPHATE KINASE
2
(Sinorhizobium
meliloti) 		4 / 4 ALA A 252
VAL A 266
PHE A 191
THR A 272
 None
 1.31A 2pkkA-3czqA:
undetectable		 2pkkA-3czqA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3czq PUTATIVE
POLYPHOSPHATE KINASE
2
(Sinorhizobium
meliloti) 		3 / 3 ASN A 196
ARG A  92
ASP A  22
 None
 0.93A 2qe6A-3czqA:
undetectable		 2qe6A-3czqA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3czq PUTATIVE
POLYPHOSPHATE KINASE
2
(Sinorhizobium
meliloti) 		3 / 3 ASN A 196
ARG A  92
ASP A  22
 None
 0.87A 2qe6B-3czqA:
undetectable		 2qe6B-3czqA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_2
(GUANINE DEAMINASE)		 3czq PUTATIVE
POLYPHOSPHATE KINASE
2
(Sinorhizobium
meliloti) 		4 / 5 HIS A 189
TRP A  77
LEU A  67
ASP A 280
 None
 1.22A 4aqlA-3czqA:
undetectable		 4aqlA-3czqA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 3czq PUTATIVE
POLYPHOSPHATE KINASE
2
(Sinorhizobium
meliloti) 		4 / 5 ARG A 263
GLY A  99
ALA A 100
GLY A  96
 None
GOL  A 303 (-4.3A)
None
GOL  A 303 (-3.0A)
 0.95A 4u9uA-3czqA:
undetectable		 4u9uA-3czqA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 3czq PUTATIVE
POLYPHOSPHATE KINASE
2
(Sinorhizobium
meliloti) 		4 / 6 TYR A 134
GLU A 158
ARG A 154
ASN A 153
 None
 0.97A 4zbqA-3czqA:
undetectable		 4zbqA-3czqA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 3czq PUTATIVE
POLYPHOSPHATE KINASE
2
(Sinorhizobium
meliloti) 		5 / 12 GLY A  99
ALA A 100
ILE A 254
ILE A 197
ILE A 195
 GOL  A 303 (-4.3A)
None
None
None
None
 0.86A 5e5jB-3czqA:
undetectable		 5e5jB-3czqA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 3czq PUTATIVE
POLYPHOSPHATE KINASE
2
(Sinorhizobium
meliloti) 		5 / 12 GLY A  99
ALA A 100
ILE A 254
ILE A 197
ILE A 195
 GOL  A 303 (-4.3A)
None
None
None
None
 0.88A 5e5kB-3czqA:
undetectable		 5e5kB-3czqA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 3czq PUTATIVE
POLYPHOSPHATE KINASE
2
(Sinorhizobium
meliloti) 		4 / 8 TRP A 251
PHE A 191
HIS A 248
THR A 137
 None
 1.13A 5hqaA-3czqA:
undetectable		 5hqaA-3czqA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3czq PUTATIVE
POLYPHOSPHATE KINASE
2
(Sinorhizobium
meliloti) 		3 / 3 THR A 104
THR A 272
LEU A 292
 None
 0.71A 5m66D-3czqA:
2.1		 5m66D-3czqA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 3czq PUTATIVE
POLYPHOSPHATE KINASE
2
(Sinorhizobium
meliloti) 		5 / 12 TYR A 134
PHE A 144
ALA A 176
THR A 244
LEU A 190
 None
 1.08A 6aybA-3czqA:
undetectable		 6aybA-3czqA:
20.77