SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3czx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 3czx PUTATIVE
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
(Neisseria
meningitidis) 		5 / 12 ILE A 168
ILE A 172
ASN A  34
VAL A  72
VAL A  48
 None
 1.05A 2nnhA-3czxA:
undetectable		 2nnhA-3czxA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 3czx PUTATIVE
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
(Neisseria
meningitidis) 		4 / 4 HIS A 130
GLU A 144
HIS A  77
HIS A  11
 ZN  A 301 ( 4.8A)
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.4A)
 1.32A 2ozrE-3czxA:
3.0		 2ozrE-3czxA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3czx PUTATIVE
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
(Neisseria
meningitidis) 		4 / 8 PHE A 122
GLU A 175
ILE A 141
ALA A  91
 None
 0.90A 3aodA-3czxA:
undetectable		 3aodA-3czxA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3czx PUTATIVE
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
(Neisseria
meningitidis) 		5 / 12 LEU A  60
ALA A 136
GLY A 140
LEU A 133
ALA A  91
 None
 1.10A 3ou6A-3czxA:
undetectable		 3ou6A-3czxA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3czx PUTATIVE
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
(Neisseria
meningitidis) 		5 / 12 LEU A  60
ALA A 136
GLY A 140
LEU A 133
ALA A  91
 None
 1.08A 3ou6B-3czxA:
undetectable		 3ou6B-3czxA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3czx PUTATIVE
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
(Neisseria
meningitidis) 		5 / 12 LEU A  60
ALA A 136
GLY A 140
LEU A 133
ALA A  91
 None
 1.06A 3ou7B-3czxA:
undetectable		 3ou7B-3czxA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3czx PUTATIVE
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
(Neisseria
meningitidis) 		5 / 12 ALA A  63
ASN A  97
ILE A 141
GLY A 139
ALA A 138
 None
 1.10A 4nkxD-3czxA:
undetectable		 4nkxD-3czxA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA608_0
(ACETYLCHOLINESTERASE)		 3czx PUTATIVE
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
(Neisseria
meningitidis) 		4 / 7 ASP A 153
THR A 152
LEU A 156
VAL A 108
 None
 1.05A 5ov9A-3czxA:
undetectable		 5ov9A-3czxA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 3czx PUTATIVE
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
(Neisseria
meningitidis) 		5 / 12 GLY A  10
HIS A  11
SER A  70
VAL A  72
ILE A  74
 None
ZN  A 301 (-3.4A)
None
None
None
 1.25A 6bxnB-3czxA:
3.2		 6bxnB-3czxA:
20.78