SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d01'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NHZ_A_486A800_1 (GLUCOCORTICOID RECEPTOR)	3d01	UNCHARACTERIZED PROTEIN (Agrobacterium fabrum)	5 / 12	LEU A 128 ASN A 127 GLY A 124 VAL A 121 LEU A 79	None	1.36A	1nhzA-3d01A: undetectable	1nhzA-3d01A: 18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VH3_A_DAHA2_1 (RANASMURFIN)	3d01	UNCHARACTERIZED PROTEIN (Agrobacterium fabrum)	5 / 9	ALA A 153 ALA A 110 PHE A 115 GLY A 65 ALA A 73	None	1.33A	2vh3A-3d01A: undetectable	2vh3A-3d01A: 24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M11_C_MXMC606_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3d01	UNCHARACTERIZED PROTEIN (Agrobacterium fabrum)	5 / 12	VAL A 132 ILE A 84 VAL A 88 LEU A 92 LEU A 85	None	1.09A	4m11C-3d01A: undetectable	4m11C-3d01A: 14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M11_D_MXMD606_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3d01	UNCHARACTERIZED PROTEIN (Agrobacterium fabrum)	5 / 12	VAL A 132 ILE A 84 VAL A 88 LEU A 92 LEU A 85	None	1.06A	4m11D-3d01A: undetectable	4m11D-3d01A: 14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R21_A_STRA601_1 (CYTOCHROME P450 FAMILY 17 POLYPEPTIDE 2)	3d01	UNCHARACTERIZED PROTEIN (Agrobacterium fabrum)	4 / 6	ALA A 153 ILE A 84 GLY A 49 ILE A 58	None	0.73A	4r21A-3d01A: undetectable	4r21A-3d01A: 17.31

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1NHZ_A_486A800_1","GLUCOCORTICOID RECEPTOR","3d01","UNCHARACTERIZED PROTEIN","Agrobacterium fabrum",5,"LEU A 128;ASN A 127;GLY A 124;VAL A 121;LEU A  79","None","1.36A","1nhzA-3d01A:undetectable","1nhzA-3d01A:18.15"],["2VH3_A_DAHA2_1","RANASMURFIN","3d01","UNCHARACTERIZED PROTEIN","Agrobacterium fabrum",5,"ALA A 153;ALA A 110;PHE A 115;GLY A  65;ALA A  73","None","1.33A","2vh3A-3d01A:undetectable","2vh3A-3d01A:24.46"],["4M11_C_MXMC606_1","PROSTAGLANDIN G\/H SYNTHASE 2","3d01","UNCHARACTERIZED PROTEIN","Agrobacterium fabrum",5,"VAL A 132;ILE A  84;VAL A  88;LEU A  92;LEU A  85","None","1.09A","4m11C-3d01A:undetectable","4m11C-3d01A:14.63"],["4M11_D_MXMD606_1","PROSTAGLANDIN G\/H SYNTHASE 2","3d01","UNCHARACTERIZED PROTEIN","Agrobacterium fabrum",5,"VAL A 132;ILE A  84;VAL A  88;LEU A  92;LEU A  85","None","1.06A","4m11D-3d01A:undetectable","4m11D-3d01A:14.63"],["4R21_A_STRA601_1","CYTOCHROME P450 FAMILY 17 POLYPEPTIDE 2","3d01","UNCHARACTERIZED PROTEIN","Agrobacterium fabrum",4,"ALA A 153;ILE A  84;GLY A  49;ILE A  58","None","0.73A","4r21A-3d01A:undetectable","4r21A-3d01A:17.31"]]