SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d02'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		4 / 8 ALA A 272
ASP A 132
ASP A 127
ILE A 309
 None
 0.78A 1p7lD-3d02A:
undetectable		 1p7lD-3d02A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		4 / 8 ALA A 272
ASP A 132
ASP A 127
ILE A 309
 None
 0.79A 1p7lC-3d02A:
undetectable		 1p7lC-3d02A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		4 / 8 ALA A 272
ASP A 132
ASP A 127
ILE A 309
 None
 0.77A 1rg9B-3d02A:
undetectable		 1rg9B-3d02A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		4 / 8 ALA A 272
ASP A 132
ASP A 127
ILE A 309
 None
 0.78A 1rg9A-3d02A:
undetectable		 1rg9A-3d02A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		4 / 8 ALA A 272
ASP A 132
ASP A 127
ILE A 309
 None
 0.78A 1rg9D-3d02A:
undetectable		 1rg9D-3d02A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		4 / 8 ALA A 272
ASP A 132
ASP A 127
ILE A 309
 None
 0.79A 1rg9C-3d02A:
undetectable		 1rg9C-3d02A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		4 / 7 GLU A 195
SER A 219
VAL A 217
MET A 208
 GOL  A   4 (-2.7A)
None
None
None
 1.21A 1tv8A-3d02A:
undetectable		 1tv8A-3d02A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		4 / 7 GLU A 195
SER A 219
VAL A 217
MET A 208
 GOL  A   4 (-2.7A)
None
None
None
 1.13A 1tv8B-3d02A:
undetectable		 1tv8B-3d02A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		5 / 12 ILE A 130
ILE A  34
SER A  35
ASP A 127
PHE A 103
 None
None
CL  A   1 (-3.0A)
None
None
 1.13A 2ejtA-3d02A:
3.6		 2ejtA-3d02A:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		4 / 7 GLU A 195
SER A 219
VAL A 217
MET A 208
 GOL  A   4 (-2.7A)
None
None
None
 1.16A 2fb2B-3d02A:
undetectable		 2fb2B-3d02A:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		4 / 8 VAL A  50
VAL A  51
GLY A  54
LYS A  55
 None
 0.27A 3bjwA-3d02A:
undetectable		 3bjwA-3d02A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		5 / 9 ALA A 277
ASN A  33
SER A  62
LEU A  81
ILE A  34
 None
 1.49A 3claA-3d02A:
undetectable		 3claA-3d02A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW1_A_STIA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		5 / 10 PHE A 136
GLY A 264
GLY A 245
TYR A 140
ILE A 261
 None
 1.21A 3fw1A-3d02A:
4.0		 3fw1A-3d02A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA278_0
(UNIVERSAL STRESS
PROTEIN)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		3 / 3 SER A 200
GLY A 227
SER A 219
 None
 0.52A 3loqA-3d02A:
2.8		 3loqA-3d02A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7V_A_SAMA992_0
(METHYLORNITHINE
SYNTHASE PYLB)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		5 / 12 GLY A 224
GLY A 221
TYR A 140
VAL A 243
ALA A 242
 None
GOL  A   4 ( 3.7A)
None
None
None
 1.24A 3t7vA-3d02A:
undetectable		 3t7vA-3d02A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		4 / 8 ALA A 272
ASP A 132
ASP A 127
ILE A 309
 None
 0.82A 4kttB-3d02A:
undetectable		 4kttB-3d02A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		4 / 8 ALA A 272
ASP A 132
ASP A 127
ILE A 309
 None
 0.82A 4kttD-3d02A:
undetectable		 4kttD-3d02A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		4 / 8 ALA A 272
ASP A 132
ASP A 127
ILE A 309
 None
 0.83A 4ndnB-3d02A:
undetectable		 4ndnB-3d02A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		4 / 8 ALA A 272
ASP A 132
ASP A 127
ILE A 309
 None
 0.81A 4ndnD-3d02A:
undetectable		 4ndnD-3d02A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		5 / 11 GLY A  49
GLY A  47
LEU A  59
VAL A  32
ALA A 277
 None
 1.03A 5o96G-3d02A:
3.2		 5o96G-3d02A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		4 / 8 ALA A 272
ASP A 132
ASP A 127
ILE A 309
 None
 0.82A 5t8sA-3d02A:
undetectable		 5t8sA-3d02A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		4 / 7 VAL A 279
VAL A  31
GLY A 273
TYR A 274
 None
 0.99A 5x80C-3d02A:
undetectable
5x80D-3d02A:
undetectable		 5x80C-3d02A:
22.34
5x80D-3d02A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR
(Klebsiella
pneumoniae) 		3 / 3 ILE A 261
THR A 262
PRO A 225
 None
 0.59A 6ncsA-3d02A:
2.8		 6ncsA-3d02A:
23.55