SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d0k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		4 / 7 TYR A  98
PHE A 150
GLY A  59
GLY A 143
 None
None
SO4  A 306 (-3.2A)
None
 0.70A 11gsB-3d0kA:
undetectable		 11gsB-3d0kA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		4 / 7 TYR A  98
PHE A 150
GLY A  59
GLY A 148
 None
None
SO4  A 306 (-3.2A)
None
 0.84A 11gsB-3d0kA:
undetectable		 11gsB-3d0kA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OAF_A_ASCA1253_0
(ASCORBATE PEROXIDASE)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		4 / 6 PRO A 219
LEU A 221
HIS A 268
ARG A 234
 None
None
SO4  A 306 (-4.0A)
SO4  A 304 (-3.4A)
 1.43A 1oafA-3d0kA:
0.0		 1oafA-3d0kA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		5 / 12 TYR A 174
THR A 175
PRO A 177
PRO A 171
LEU A 192
 None
 1.13A 1z9hA-3d0kA:
undetectable		 1z9hA-3d0kA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		5 / 12 TYR A 174
THR A 175
PRO A 177
SER A 157
LEU A 192
 None
 1.42A 1z9hA-3d0kA:
undetectable		 1z9hA-3d0kA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		5 / 12 TYR A 174
THR A 175
PRO A 177
PRO A 171
LEU A 192
 None
 1.14A 1z9hB-3d0kA:
undetectable		 1z9hB-3d0kA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		5 / 12 TYR A 174
THR A 175
PRO A 177
SER A 157
LEU A 192
 None
 1.43A 1z9hB-3d0kA:
undetectable		 1z9hB-3d0kA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		5 / 12 TYR A 174
THR A 175
PRO A 177
PRO A 171
LEU A 192
 None
 1.14A 1z9hC-3d0kA:
undetectable		 1z9hC-3d0kA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		5 / 12 TYR A 174
THR A 175
PRO A 177
SER A 157
LEU A 192
 None
 1.43A 1z9hC-3d0kA:
undetectable		 1z9hC-3d0kA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		4 / 5 PHE A  37
PHE A  87
PHE A 150
VAL A 124
 None
 1.13A 2lh6A-3d0kA:
undetectable		 2lh6A-3d0kA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_B_SAMB400_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		5 / 9 ALA A 272
VAL A 276
GLY A 267
GLY A 210
ALA A 296
 None
 0.93A 2z0yB-3d0kA:
2.6		 2z0yB-3d0kA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		3 / 3 PRO A  52
LEU A  80
ARG A  77
 None
 0.81A 3aqiA-3d0kA:
4.1		 3aqiA-3d0kA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		5 / 12 ASP A 213
VAL A  56
GLY A  59
SER A 145
ALA A 169
 None
None
SO4  A 306 (-3.2A)
SO4  A 304 ( 2.7A)
None
 0.99A 3keeB-3d0kA:
undetectable		 3keeB-3d0kA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		5 / 12 ASP A 213
VAL A  56
GLY A  59
SER A 145
ALA A 169
 None
None
SO4  A 306 (-3.2A)
SO4  A 304 ( 2.7A)
None
 0.98A 3keeC-3d0kA:
undetectable		 3keeC-3d0kA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		5 / 11 ALA A 272
ILE A 266
GLY A 267
SER A 274
LEU A 208
 None
 1.24A 3kw2A-3d0kA:
2.5		 3kw2A-3d0kA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		4 / 8 TYR A  98
PHE A 150
GLY A  59
GLY A 143
 None
None
SO4  A 306 (-3.2A)
None
 0.73A 3n9jB-3d0kA:
undetectable		 3n9jB-3d0kA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		5 / 12 HIS A 268
ASP A 213
GLY A  59
SER A 145
ALA A 169
 SO4  A 306 (-4.0A)
None
SO4  A 306 (-3.2A)
SO4  A 304 ( 2.7A)
None
 1.20A 3sueB-3d0kA:
undetectable		 3sueB-3d0kA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		4 / 7 ALA A 215
ILE A 214
ARG A 234
GLY A 267
 None
None
SO4  A 304 (-3.4A)
None
 0.85A 3v4tH-3d0kA:
undetectable		 3v4tH-3d0kA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		3 / 3 ASP A  28
ARG A 123
ASP A  34
 None
 0.85A 4fp9A-3d0kA:
undetectable		 4fp9A-3d0kA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		3 / 3 ASP A  28
ARG A 123
ASP A  34
 None
 0.71A 4fp9C-3d0kA:
undetectable		 4fp9C-3d0kA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		3 / 3 ASP A  28
ARG A 123
ASP A  34
 None
 0.72A 4fp9F-3d0kA:
undetectable		 4fp9F-3d0kA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		3 / 3 ALA A 103
GLN A 149
GLY A 172
 None
SO4  A 304 (-3.8A)
SO4  A 304 (-3.2A)
 0.63A 4odoC-3d0kA:
undetectable		 4odoC-3d0kA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		4 / 8 SER A 145
ALA A 146
HIS A 268
LEU A  61
 SO4  A 304 ( 2.7A)
SO4  A 304 (-4.1A)
SO4  A 306 (-4.0A)
SO4  A 306 ( 4.5A)
 1.16A 5dzkd-3d0kA:
undetectable
5dzkr-3d0kA:
undetectable		 5dzkd-3d0kA:
21.36
5dzkr-3d0kA:
0.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		5 / 11 ILE A 266
GLY A 267
ALA A 272
PHE A 142
LEU A 295
 None
 1.32A 5hw4B-3d0kA:
undetectable		 5hw4B-3d0kA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		3 / 3 THR A 193
PRO A 110
ARG A 111
 None
 0.79A 5nd7B-3d0kA:
undetectable		 5nd7B-3d0kA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		5 / 12 GLN A 275
ALA A 278
GLU A 291
LEU A 295
ILE A 266
 None
 0.94A 5vlmG-3d0kA:
undetectable		 5vlmG-3d0kA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_1
(RIBOFLAVIN LYASE)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		5 / 12 ALA A 227
GLY A 172
GLY A 101
ALA A 103
VAL A  95
 None
SO4  A 304 (-3.2A)
None
None
SO4  A 308 ( 3.4A)
 0.84A 5w4zB-3d0kA:
undetectable		 5w4zB-3d0kA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_F_BEZF201_0
(NS3 PROTEASE)		 3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC
(Bordetella
parapertussis) 		4 / 5 HIS A 268
ALA A 146
SER A 145
TYR A  67
 SO4  A 306 (-4.0A)
SO4  A 304 (-4.1A)
SO4  A 304 ( 2.7A)
SO4  A 306 (-4.7A)
 1.44A 5yodF-3d0kA:
undetectable		 5yodF-3d0kA:
20.07