SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d12'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3d12 EPHRIN-B3
(Mus
musculus) 		4 / 7 SER B 121
PHE B 117
PHE B 113
LEU B  61
 None
 1.04A 1qcaA-3d12B:
undetectable		 1qcaA-3d12B:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 3d12 EPHRIN-B3
(Mus
musculus) 		5 / 12 GLY B  89
LEU B 164
ILE B 138
VAL B  84
LEU B  83
 None
 1.13A 4fr0A-3d12B:
undetectable		 4fr0A-3d12B:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3d12 EPHRIN-B3
(Mus
musculus) 		5 / 12 VAL B 167
LEU B  50
ILE B 138
ILE B 115
LEU B 101
 None
 1.10A 5mugA-3d12B:
undetectable		 5mugA-3d12B:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3d12 EPHRIN-B3
(Mus
musculus) 		5 / 12 TYR B  51
LEU B  30
TRP B  35
LEU B 165
VAL B 163
 None
 1.19A 6a93B-3d12B:
undetectable		 6a93B-3d12B:
17.56