SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d19'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		4 / 8 ARG A 236
HIS A  37
ARG A  32
VAL A 256
 None
FE  A 302 (-3.4A)
None
None
 1.34A 1u1jA-3d19A:
undetectable		 1u1jA-3d19A:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		4 / 6 SER A 246
ILE A 239
ALA A 235
ALA A 184
 None
 0.94A 1w0gA-3d19A:
0.4		 1w0gA-3d19A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		4 / 7 LEU A 112
LEU A  41
ALA A  56
PHE A  99
 None
 0.76A 2vcvG-3d19A:
undetectable		 2vcvG-3d19A:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		4 / 8 LEU A 112
LEU A  41
ALA A  56
PHE A  99
 None
 0.79A 2vcvP-3d19A:
undetectable		 2vcvP-3d19A:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 124
ILE A 161
HIS A 165
HIS A 255
HIS A  37
 MG  A 301 (-3.5A)
MG  A 301 ( 4.6A)
MG  A 301 (-3.4A)
FE  A 302 (-3.5A)
FE  A 302 (-3.4A)
 1.33A 2zweA-3d19A:
undetectable
2zweB-3d19A:
undetectable		 2zweA-3d19A:
22.67
2zweB-3d19A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 255
ILE A  33
HIS A  37
HIS A 124
HIS A 165
 FE  A 302 (-3.5A)
FE  A 302 (-4.3A)
FE  A 302 (-3.4A)
MG  A 301 (-3.5A)
MG  A 301 (-3.4A)
 1.35A 2zweA-3d19A:
undetectable
2zweB-3d19A:
undetectable		 2zweA-3d19A:
22.67
2zweB-3d19A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 124
ILE A 161
HIS A 165
HIS A 255
HIS A  37
 MG  A 301 (-3.5A)
MG  A 301 ( 4.6A)
MG  A 301 (-3.4A)
FE  A 302 (-3.5A)
FE  A 302 (-3.4A)
 1.27A 2zwfA-3d19A:
undetectable
2zwfB-3d19A:
undetectable		 2zwfA-3d19A:
22.67
2zwfB-3d19A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 255
ILE A  33
HIS A  37
HIS A 124
HIS A 165
 FE  A 302 (-3.5A)
FE  A 302 (-4.3A)
FE  A 302 (-3.4A)
MG  A 301 (-3.5A)
MG  A 301 (-3.4A)
 1.28A 2zwfA-3d19A:
undetectable
2zwfB-3d19A:
undetectable		 2zwfA-3d19A:
22.67
2zwfB-3d19A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 124
ILE A 161
HIS A 165
HIS A 255
HIS A  37
 MG  A 301 (-3.5A)
MG  A 301 ( 4.6A)
MG  A 301 (-3.4A)
FE  A 302 (-3.5A)
FE  A 302 (-3.4A)
 1.27A 2zwgA-3d19A:
undetectable
2zwgB-3d19A:
undetectable		 2zwgA-3d19A:
22.67
2zwgB-3d19A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 255
ILE A  33
HIS A  37
HIS A 124
HIS A 165
 FE  A 302 (-3.5A)
FE  A 302 (-4.3A)
FE  A 302 (-3.4A)
MG  A 301 (-3.5A)
MG  A 301 (-3.4A)
 1.28A 2zwgA-3d19A:
undetectable
2zwgB-3d19A:
undetectable		 2zwgA-3d19A:
22.67
2zwgB-3d19A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		3 / 3 GLU A 265
GLU A  26
ASN A  25
 None
 0.76A 3lp9B-3d19A:
undetectable
3lp9D-3d19A:
undetectable		 3lp9B-3d19A:
21.23
3lp9D-3d19A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		4 / 7 HIS A 255
GLU A  26
GLU A 128
PHE A 157
 FE  A 302 (-3.5A)
None
FE  A 302 ( 2.4A)
None
 1.38A 3ql6A-3d19A:
undetectable		 3ql6A-3d19A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		4 / 8 ASP A 237
ARG A  32
ASP A 254
GLU A 240
 None
 0.89A 4gkhF-3d19A:
undetectable		 4gkhF-3d19A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		4 / 7 PHE A 158
ARG A 262
ILE A 266
TYR A 270
 None
 1.33A 5a06B-3d19A:
undetectable		 5a06B-3d19A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 124
ILE A 161
HIS A 165
HIS A 255
HIS A  37
 MG  A 301 (-3.5A)
MG  A 301 ( 4.6A)
MG  A 301 (-3.4A)
FE  A 302 (-3.5A)
FE  A 302 (-3.4A)
 1.32A 5z0fA-3d19A:
undetectable
5z0fB-3d19A:
undetectable		 5z0fA-3d19A:
15.94
5z0fB-3d19A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 255
ILE A  33
HIS A  37
HIS A 124
HIS A 165
 FE  A 302 (-3.5A)
FE  A 302 (-4.3A)
FE  A 302 (-3.4A)
MG  A 301 (-3.5A)
MG  A 301 (-3.4A)
 1.33A 5z0fA-3d19A:
undetectable
5z0fB-3d19A:
undetectable		 5z0fA-3d19A:
15.94
5z0fB-3d19A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 124
ILE A 161
HIS A 165
HIS A 255
HIS A  37
 MG  A 301 (-3.5A)
MG  A 301 ( 4.6A)
MG  A 301 (-3.4A)
FE  A 302 (-3.5A)
FE  A 302 (-3.4A)
 1.32A 5z0gA-3d19A:
undetectable
5z0gB-3d19A:
undetectable		 5z0gA-3d19A:
15.94
5z0gB-3d19A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 255
ILE A  33
HIS A  37
HIS A 124
HIS A 165
 FE  A 302 (-3.5A)
FE  A 302 (-4.3A)
FE  A 302 (-3.4A)
MG  A 301 (-3.5A)
MG  A 301 (-3.4A)
 1.34A 5z0gA-3d19A:
undetectable
5z0gB-3d19A:
undetectable		 5z0gA-3d19A:
15.94
5z0gB-3d19A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 124
ILE A 161
HIS A 165
HIS A 255
HIS A  37
 MG  A 301 (-3.5A)
MG  A 301 ( 4.6A)
MG  A 301 (-3.4A)
FE  A 302 (-3.5A)
FE  A 302 (-3.4A)
 1.26A 5z0hA-3d19A:
undetectable
5z0hB-3d19A:
undetectable		 5z0hA-3d19A:
15.94
5z0hB-3d19A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 255
ILE A  33
HIS A  37
HIS A 124
HIS A 165
 FE  A 302 (-3.5A)
FE  A 302 (-4.3A)
FE  A 302 (-3.4A)
MG  A 301 (-3.5A)
MG  A 301 (-3.4A)
 1.27A 5z0hA-3d19A:
undetectable
5z0hB-3d19A:
undetectable		 5z0hA-3d19A:
15.94
5z0hB-3d19A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 124
ILE A 161
HIS A 165
HIS A 255
HIS A  37
 MG  A 301 (-3.5A)
MG  A 301 ( 4.6A)
MG  A 301 (-3.4A)
FE  A 302 (-3.5A)
FE  A 302 (-3.4A)
 1.31A 5z0iA-3d19A:
undetectable
5z0iB-3d19A:
undetectable		 5z0iA-3d19A:
15.94
5z0iB-3d19A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 255
ILE A  33
HIS A  37
HIS A 124
HIS A 165
 FE  A 302 (-3.5A)
FE  A 302 (-4.3A)
FE  A 302 (-3.4A)
MG  A 301 (-3.5A)
MG  A 301 (-3.4A)
 1.32A 5z0iA-3d19A:
undetectable
5z0iB-3d19A:
undetectable		 5z0iA-3d19A:
15.94
5z0iB-3d19A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 124
ILE A 161
HIS A 165
HIS A 255
HIS A  37
 MG  A 301 (-3.5A)
MG  A 301 ( 4.6A)
MG  A 301 (-3.4A)
FE  A 302 (-3.5A)
FE  A 302 (-3.4A)
 1.28A 5z0jA-3d19A:
undetectable
5z0jB-3d19A:
undetectable		 5z0jA-3d19A:
15.94
5z0jB-3d19A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 255
ILE A  33
HIS A  37
HIS A 124
HIS A 165
 FE  A 302 (-3.5A)
FE  A 302 (-4.3A)
FE  A 302 (-3.4A)
MG  A 301 (-3.5A)
MG  A 301 (-3.4A)
 1.28A 5z0jA-3d19A:
undetectable
5z0jB-3d19A:
undetectable		 5z0jA-3d19A:
15.94
5z0jB-3d19A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 124
ILE A 161
HIS A 165
HIS A 255
HIS A  37
 MG  A 301 (-3.5A)
MG  A 301 ( 4.6A)
MG  A 301 (-3.4A)
FE  A 302 (-3.5A)
FE  A 302 (-3.4A)
 1.30A 5z0kA-3d19A:
undetectable
5z0kB-3d19A:
undetectable		 5z0kA-3d19A:
15.94
5z0kB-3d19A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 255
ILE A  33
HIS A  37
HIS A 124
HIS A 165
 FE  A 302 (-3.5A)
FE  A 302 (-4.3A)
FE  A 302 (-3.4A)
MG  A 301 (-3.5A)
MG  A 301 (-3.4A)
 1.31A 5z0kA-3d19A:
undetectable
5z0kB-3d19A:
undetectable		 5z0kA-3d19A:
15.94
5z0kB-3d19A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 124
ILE A 161
HIS A 165
HIS A 255
HIS A  37
 MG  A 301 (-3.5A)
MG  A 301 ( 4.6A)
MG  A 301 (-3.4A)
FE  A 302 (-3.5A)
FE  A 302 (-3.4A)
 1.27A 5z0lA-3d19A:
undetectable
5z0lB-3d19A:
undetectable		 5z0lA-3d19A:
15.94
5z0lB-3d19A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 255
ILE A  33
HIS A  37
HIS A 124
HIS A 165
 FE  A 302 (-3.5A)
FE  A 302 (-4.3A)
FE  A 302 (-3.4A)
MG  A 301 (-3.5A)
MG  A 301 (-3.4A)
 1.28A 5z0lA-3d19A:
undetectable
5z0lB-3d19A:
undetectable		 5z0lA-3d19A:
15.94
5z0lB-3d19A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 124
ILE A 161
HIS A 165
HIS A 255
HIS A  37
 MG  A 301 (-3.5A)
MG  A 301 ( 4.6A)
MG  A 301 (-3.4A)
FE  A 302 (-3.5A)
FE  A 302 (-3.4A)
 1.27A 5z0mA-3d19A:
undetectable
5z0mB-3d19A:
undetectable		 5z0mA-3d19A:
15.94
5z0mB-3d19A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		5 / 11 HIS A 255
ILE A  33
HIS A  37
HIS A 124
HIS A 165
 FE  A 302 (-3.5A)
FE  A 302 (-4.3A)
FE  A 302 (-3.4A)
MG  A 301 (-3.5A)
MG  A 301 (-3.4A)
 1.27A 5z0mA-3d19A:
undetectable
5z0mB-3d19A:
undetectable		 5z0mA-3d19A:
15.94
5z0mB-3d19A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		4 / 6 PHE A 231
ARG A 229
LEU A 228
ALA A 184
 None
 1.09A 6b89B-3d19A:
undetectable		 6b89B-3d19A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 3d19 CONSERVED
METALLOPROTEIN
(Bacillus
cereus) 		4 / 7 PHE A 231
ARG A 229
LEU A 228
ALA A 184
 None
 1.29A 6b89A-3d19A:
undetectable		 6b89A-3d19A:
14.95