SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d1d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
3d1d RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3

(Schizosaccharomy
ces
pombe)
4 / 7 LEU A 477
GLN A 478
LEU A 443
PHE A 449
None
1.07A 1v55C-3d1dA:
undetectable
1v55J-3d1dA:
undetectable
1v55C-3d1dA:
19.47
1v55J-3d1dA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
3d1d RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3

(Schizosaccharomy
ces
pombe)
4 / 7 LEU A 477
GLN A 478
LEU A 443
PHE A 449
None
1.04A 1v55P-3d1dA:
undetectable
1v55W-3d1dA:
undetectable
1v55P-3d1dA:
19.47
1v55W-3d1dA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d1d RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3

(Schizosaccharomy
ces
pombe)
4 / 7 LEU A 477
GLN A 478
LEU A 443
PHE A 449
None
0.95A 2dysC-3d1dA:
undetectable
2dysJ-3d1dA:
undetectable
2dysC-3d1dA:
19.47
2dysJ-3d1dA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d1d RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3

(Schizosaccharomy
ces
pombe)
4 / 7 LEU A 477
GLN A 478
LEU A 443
PHE A 449
None
1.03A 2eijC-3d1dA:
undetectable
2eijJ-3d1dA:
undetectable
2eijC-3d1dA:
19.47
2eijJ-3d1dA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d1d RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3

(Schizosaccharomy
ces
pombe)
4 / 7 LEU A 477
GLN A 478
LEU A 443
PHE A 449
None
0.97A 2eimC-3d1dA:
undetectable
2eimJ-3d1dA:
undetectable
2eimC-3d1dA:
19.47
2eimJ-3d1dA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d1d RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3

(Schizosaccharomy
ces
pombe)
4 / 7 LEU A 477
GLN A 478
LEU A 443
PHE A 449
None
1.03A 2einC-3d1dA:
undetectable
2einJ-3d1dA:
undetectable
2einC-3d1dA:
19.47
2einJ-3d1dA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d1d RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3

(Schizosaccharomy
ces
pombe)
4 / 6 LEU A 477
GLN A 478
LEU A 443
PHE A 449
None
1.10A 2einP-3d1dA:
undetectable
2einW-3d1dA:
undetectable
2einP-3d1dA:
19.47
2einW-3d1dA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d1d RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3

(Schizosaccharomy
ces
pombe)
4 / 6 LEU A 477
GLN A 478
LEU A 443
PHE A 449
None
1.02A 2zxwP-3d1dA:
undetectable
2zxwW-3d1dA:
undetectable
2zxwP-3d1dA:
19.47
2zxwW-3d1dA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d1d RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3

(Schizosaccharomy
ces
pombe)
4 / 6 LEU A 477
GLN A 478
LEU A 443
PHE A 449
None
0.93A 3ag1C-3d1dA:
undetectable
3ag1J-3d1dA:
undetectable
3ag1C-3d1dA:
19.47
3ag1J-3d1dA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JJK_A_FOLA601_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)
3d1d RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3

(Schizosaccharomy
ces
pombe)
4 / 8 ALA A 512
PRO A 510
LEU A 505
LEU A 537
None
0.97A 4jjkA-3d1dA:
undetectable
4jjkA-3d1dA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3d1d RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3

(Schizosaccharomy
ces
pombe)
5 / 7 LEU A 477
GLN A 475
PHE A 473
LEU A 443
PHE A 449
None
1.49A 5b1aP-3d1dA:
undetectable
5b1aW-3d1dA:
undetectable
5b1aP-3d1dA:
19.47
5b1aW-3d1dA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3d1d RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3

(Schizosaccharomy
ces
pombe)
5 / 7 LEU A 477
GLN A 475
PHE A 473
LEU A 443
PHE A 449
None
1.49A 5iy5C-3d1dA:
undetectable
5iy5J-3d1dA:
undetectable
5iy5C-3d1dA:
19.62
5iy5J-3d1dA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3d1d RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3

(Schizosaccharomy
ces
pombe)
5 / 7 LEU A 477
GLN A 475
PHE A 473
LEU A 443
PHE A 449
None
1.45A 5z84C-3d1dA:
undetectable
5z84J-3d1dA:
undetectable
5z84C-3d1dA:
19.47
5z84J-3d1dA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3d1d RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3

(Schizosaccharomy
ces
pombe)
4 / 7 LEU A 477
GLN A 478
LEU A 443
PHE A 449
None
0.93A 5zcoC-3d1dA:
undetectable
5zcoJ-3d1dA:
undetectable
5zcoC-3d1dA:
19.47
5zcoJ-3d1dA:
20.34