SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d1l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3d1l PUTATIVE NADP
OXIDOREDUCTASE
BF3122
(Bacteroides
fragilis) 		5 / 11 ALA A 140
GLU A 139
ARG A 168
ILE A  70
LEU A  94
 None
 1.22A 1g50A-3d1lA:
undetectable		 1g50A-3d1lA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 3d1l PUTATIVE NADP
OXIDOREDUCTASE
BF3122
(Bacteroides
fragilis) 		4 / 7 ALA A  93
GLU A  92
LEU A  94
VAL A  96
 None
 0.89A 1hk2A-3d1lA:
2.3		 1hk2A-3d1lA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)		 3d1l PUTATIVE NADP
OXIDOREDUCTASE
BF3122
(Bacteroides
fragilis) 		3 / 3 LYS A 213
GLY A 225
PRO A 226
 None
 0.96A 2hreB-3d1lA:
undetectable		 2hreB-3d1lA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d1l PUTATIVE NADP
OXIDOREDUCTASE
BF3122
(Bacteroides
fragilis) 		4 / 6 ILE A  13
ILE A 152
LEU A  73
PHE A  78
 None
 1.08A 3adsA-3d1lA:
undetectable		 3adsA-3d1lA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJK_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3d1l PUTATIVE NADP
OXIDOREDUCTASE
BF3122
(Bacteroides
fragilis) 		5 / 12 PHE A 117
THR A   8
ILE A  10
LEU A  26
ILE A 152
 None
 1.05A 4kjkA-3d1lA:
undetectable		 4kjkA-3d1lA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)		 3d1l PUTATIVE NADP
OXIDOREDUCTASE
BF3122
(Bacteroides
fragilis) 		4 / 7 ASN A 105
VAL A 116
GLU A 139
ARG A 168
 None
 0.97A 4mv7A-3d1lA:
6.6		 4mv7A-3d1lA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX6_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3d1l PUTATIVE NADP
OXIDOREDUCTASE
BF3122
(Bacteroides
fragilis) 		5 / 12 PHE A 117
THR A   8
ILE A  10
LEU A  26
ILE A 152
 None
 1.11A 4nx6A-3d1lA:
undetectable		 4nx6A-3d1lA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3d1l PUTATIVE NADP
OXIDOREDUCTASE
BF3122
(Bacteroides
fragilis) 		5 / 12 GLY A 115
SER A 141
ASP A 145
ASN A 105
GLY A 100
 None
 1.21A 4obwC-3d1lA:
4.8		 4obwC-3d1lA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3d1l PUTATIVE NADP
OXIDOREDUCTASE
BF3122
(Bacteroides
fragilis) 		5 / 12 GLY A 115
SER A 141
ASP A 145
ILE A 102
GLY A 100
 None
 1.10A 4obwC-3d1lA:
4.8		 4obwC-3d1lA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3d1l PUTATIVE NADP
OXIDOREDUCTASE
BF3122
(Bacteroides
fragilis) 		5 / 10 LEU A 149
LEU A 156
LEU A  22
ILE A  70
LEU A  94
 None
 1.07A 4odoA-3d1lA:
undetectable		 4odoA-3d1lA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3d1l PUTATIVE NADP
OXIDOREDUCTASE
BF3122
(Bacteroides
fragilis) 		5 / 10 LEU A 149
LEU A 156
LEU A  22
ILE A  70
LEU A  94
 None
 1.02A 4odoB-3d1lA:
undetectable		 4odoB-3d1lA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3d1l PUTATIVE NADP
OXIDOREDUCTASE
BF3122
(Bacteroides
fragilis) 		5 / 10 LEU A 149
LEU A 156
LEU A  22
ILE A  70
LEU A  94
 None
 1.03A 4odoC-3d1lA:
undetectable		 4odoC-3d1lA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 3d1l PUTATIVE NADP
OXIDOREDUCTASE
BF3122
(Bacteroides
fragilis) 		6 / 12 ALA A  23
ILE A  10
ILE A  70
GLY A  14
VAL A  34
ILE A  33
 None
 1.47A 4q1xB-3d1lA:
undetectable		 4q1xB-3d1lA:
17.24