SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d1n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 3d1n POU DOMAIN, CLASS 6,
TRANSCRIPTION FACTOR
1
(Homo
sapiens) 		4 / 5 GLY I 162
LEU I 163
THR I 164
ARG I 158
 None
 1.11A 1ekjF-3d1nI:
undetectable
1ekjG-3d1nI:
undetectable		 1ekjF-3d1nI:
22.22
1ekjG-3d1nI:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 3d1n POU DOMAIN, CLASS 6,
TRANSCRIPTION FACTOR
1
(Homo
sapiens) 		3 / 3 GLU I 189
ALA I 184
SER I 181
 None
 0.70A 1errB-3d1nI:
undetectable		 1errB-3d1nI:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)		 3d1n POU DOMAIN, CLASS 6,
TRANSCRIPTION FACTOR
1
(Homo
sapiens) 		5 / 12 ILE I 147
PHE I 150
ALA I 151
ILE I 185
ALA I 184
 None
 1.11A 3nxuB-3d1nI:
undetectable		 3nxuB-3d1nI:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_2
(ADENOSINE KINASE,
PUTATIVE)		 3d1n POU DOMAIN, CLASS 6,
TRANSCRIPTION FACTOR
1
(Homo
sapiens) 		4 / 5 LEU I 163
ALA I 212
MET I 172
PHE I 226
 None
 1.33A 3uq6A-3d1nI:
undetectable		 3uq6A-3d1nI:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 3d1n POU DOMAIN, CLASS 6,
TRANSCRIPTION FACTOR
1
(Homo
sapiens) 		4 / 8 ASN I 256
PRO I 257
GLU I 254
PHE I 253
 None
 1.12A 5oh1C-3d1nI:
undetectable		 5oh1C-3d1nI:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 3d1n POU DOMAIN, CLASS 6,
TRANSCRIPTION FACTOR
1
(Homo
sapiens) 		5 / 12 ILE I 147
PHE I 150
ALA I 151
ILE I 185
ALA I 184
 None
 1.12A 5vc0A-3d1nI:
undetectable		 5vc0A-3d1nI:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 3d1n POU DOMAIN, CLASS 6,
TRANSCRIPTION FACTOR
1
(Homo
sapiens) 		4 / 7 PHE I 226
ALA I 171
GLN I 170
GLN I 217
 None
 1.25A 6b89A-3d1nI:
undetectable		 6b89A-3d1nI:
16.78