SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d23'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.26A 1v54A-3d23B:
undetectable
1v54C-3d23B:
undetectable
1v54A-3d23B:
20.69
1v54C-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.22A 1v54N-3d23B:
undetectable
1v54P-3d23B:
undetectable
1v54N-3d23B:
20.69
1v54P-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.25A 1v55A-3d23B:
undetectable
1v55C-3d23B:
undetectable
1v55A-3d23B:
20.69
1v55C-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.22A 1v55C-3d23B:
undetectable
1v55N-3d23B:
undetectable
1v55P-3d23B:
undetectable
1v55C-3d23B:
19.93
1v55N-3d23B:
20.69
1v55P-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 8 SER B 144
TYR B 161
HIS B 172
HIS B 163
None
1.34A 2bteD-3d23B:
undetectable
2bteD-3d23B:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.25A 2dyrA-3d23B:
undetectable
2dyrC-3d23B:
undetectable
2dyrA-3d23B:
20.69
2dyrC-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.24A 2dyrN-3d23B:
undetectable
2dyrP-3d23B:
undetectable
2dyrN-3d23B:
20.69
2dyrP-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 6 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.25A 2dysA-3d23B:
undetectable
2dysC-3d23B:
undetectable
2dysA-3d23B:
20.69
2dysC-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 6 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.24A 2dysN-3d23B:
undetectable
2dysP-3d23B:
undetectable
2dysN-3d23B:
20.69
2dysP-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.24A 2eijA-3d23B:
undetectable
2eijC-3d23B:
undetectable
2eijA-3d23B:
20.69
2eijC-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.22A 2eijN-3d23B:
undetectable
2eijP-3d23B:
undetectable
2eijN-3d23B:
20.69
2eijP-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.23A 2eikA-3d23B:
undetectable
2eikC-3d23B:
undetectable
2eikA-3d23B:
20.69
2eikC-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.23A 2eikN-3d23B:
undetectable
2eikP-3d23B:
undetectable
2eikN-3d23B:
20.69
2eikP-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.25A 2eilA-3d23B:
undetectable
2eilC-3d23B:
undetectable
2eilA-3d23B:
20.69
2eilC-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.22A 2eilN-3d23B:
undetectable
2eilP-3d23B:
undetectable
2eilN-3d23B:
20.69
2eilP-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 6 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.26A 2eimA-3d23B:
undetectable
2eimC-3d23B:
undetectable
2eimA-3d23B:
20.69
2eimC-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 6 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.27A 2eimN-3d23B:
undetectable
2eimP-3d23B:
undetectable
2eimN-3d23B:
20.69
2eimP-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 6 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.31A 2einA-3d23B:
undetectable
2einC-3d23B:
undetectable
2einA-3d23B:
20.69
2einC-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 6 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.29A 2einN-3d23B:
undetectable
2einP-3d23B:
undetectable
2einN-3d23B:
20.69
2einP-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 6 ASP B 197
ARG B 131
THR B 129
ASP B 286
None
1.13A 2j2pE-3d23B:
undetectable
2j2pF-3d23B:
undetectable
2j2pE-3d23B:
21.64
2j2pF-3d23B:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.22A 2y69A-3d23B:
undetectable
2y69C-3d23B:
undetectable
2y69A-3d23B:
20.69
2y69C-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 6 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.27A 2zxwA-3d23B:
undetectable
2zxwC-3d23B:
undetectable
2zxwA-3d23B:
20.69
2zxwC-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 6 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.27A 2zxwN-3d23B:
undetectable
2zxwP-3d23B:
undetectable
2zxwN-3d23B:
20.69
2zxwP-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.23A 3abkA-3d23B:
undetectable
3abkC-3d23B:
undetectable
3abkA-3d23B:
20.69
3abkC-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.23A 3abkN-3d23B:
undetectable
3abkP-3d23B:
undetectable
3abkN-3d23B:
20.69
3abkP-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.26A 3abmN-3d23B:
undetectable
3abmP-3d23B:
undetectable
3abmN-3d23B:
20.69
3abmP-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 6 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.23A 3ag1A-3d23B:
undetectable
3ag1C-3d23B:
undetectable
3ag1A-3d23B:
20.69
3ag1C-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 6 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.25A 3ag1N-3d23B:
undetectable
3ag1P-3d23B:
undetectable
3ag1N-3d23B:
20.69
3ag1P-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.22A 3ag2A-3d23B:
undetectable
3ag2C-3d23B:
undetectable
3ag2A-3d23B:
20.69
3ag2C-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.22A 3ag2N-3d23B:
undetectable
3ag2P-3d23B:
undetectable
3ag2N-3d23B:
20.69
3ag2P-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.24A 3ag3A-3d23B:
undetectable
3ag3C-3d23B:
undetectable
3ag3A-3d23B:
20.69
3ag3C-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.22A 3ag3N-3d23B:
undetectable
3ag3P-3d23B:
undetectable
3ag3N-3d23B:
20.69
3ag3P-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.25A 3ag4A-3d23B:
undetectable
3ag4C-3d23B:
undetectable
3ag4A-3d23B:
20.69
3ag4C-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.25A 3ag4N-3d23B:
undetectable
3ag4P-3d23B:
undetectable
3ag4N-3d23B:
20.69
3ag4P-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 6 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.27A 3asnA-3d23B:
undetectable
3asnC-3d23B:
undetectable
3asnA-3d23B:
20.69
3asnC-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 THR B 129
GLY B 109
THR B 111
VAL B 202
None
0.89A 4qwpB-3d23B:
undetectable
4qwpB-3d23B:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJL_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
5 / 12 SER B 240
PHE B 273
GLU B 287
LEU B 248
GLY B 109
None
1.48A 4zjlA-3d23B:
undetectable
4zjlA-3d23B:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.24A 5b1aN-3d23B:
undetectable
5b1aP-3d23B:
undetectable
5b1aN-3d23B:
20.69
5b1aP-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.22A 5b1bN-3d23B:
undetectable
5b1bP-3d23B:
undetectable
5b1bN-3d23B:
20.69
5b1bP-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 8 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.24A 5b3sA-3d23B:
undetectable
5b3sC-3d23B:
undetectable
5b3sP-3d23B:
undetectable
5b3sA-3d23B:
20.69
5b3sC-3d23B:
19.93
5b3sP-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.24A 5b3sN-3d23B:
undetectable
5b3sP-3d23B:
undetectable
5b3sN-3d23B:
20.69
5b3sP-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
5 / 12 TYR B  54
MET B 162
GLN B 164
GLY B 146
LEU B  27
None
1.46A 5g6sB-3d23B:
undetectable
5g6sC-3d23B:
undetectable
5g6sB-3d23B:
22.26
5g6sC-3d23B:
22.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GWZ_D_010D6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
PEDV MAIN PROTEASE)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
3 / 3 MET B  25
HIS B  41
GLY B 143
None
0.44A 5gwzB-3d23B:
19.9
5gwzB-3d23B:
44.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.24A 5iy5A-3d23B:
undetectable
5iy5C-3d23B:
undetectable
5iy5A-3d23B:
20.69
5iy5C-3d23B:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 6 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.24A 5x19N-3d23B:
undetectable
5x19P-3d23B:
undetectable
5x19N-3d23B:
20.69
5x19P-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 6 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.29A 5x1bN-3d23B:
undetectable
5x1bP-3d23B:
undetectable
5x1bN-3d23B:
20.69
5x1bP-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.21A 5x1fA-3d23B:
undetectable
5x1fC-3d23B:
undetectable
5x1fP-3d23B:
undetectable
5x1fA-3d23B:
20.69
5x1fC-3d23B:
19.93
5x1fP-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.28A 5x1fN-3d23B:
undetectable
5x1fP-3d23B:
undetectable
5x1fN-3d23B:
20.69
5x1fP-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.26A 5z85C-3d23B:
undetectable
5z85N-3d23B:
undetectable
5z85P-3d23B:
undetectable
5z85C-3d23B:
19.93
5z85N-3d23B:
20.69
5z85P-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.26A 5zcqN-3d23B:
undetectable
5zcqP-3d23B:
undetectable
5zcqN-3d23B:
20.69
5zcqP-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 6 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.25A 6nknA-3d23B:
undetectable
6nknC-3d23B:
undetectable
6nknA-3d23B:
20.69
6nknC-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.22A 6nmfN-3d23B:
undetectable
6nmfP-3d23B:
undetectable
6nmfN-3d23B:
20.69
6nmfP-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 6 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.27A 6nmpA-3d23B:
undetectable
6nmpC-3d23B:
undetectable
6nmpA-3d23B:
20.69
6nmpC-3d23B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3d23 3C-LIKE PROTEINASE
(Human
coronavirus
HKU1)
4 / 7 HIS B  41
ASP B 176
THR B 175
TYR B 161
None
1.27A 6nmpN-3d23B:
undetectable
6nmpP-3d23B:
undetectable
6nmpN-3d23B:
20.69
6nmpP-3d23B:
19.93