SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d2s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLD_A_ASCA130_0
(CYTOCHROME C')		 3d2s MUSCLEBLIND-LIKE
PROTEIN 1
(Homo
sapiens) 		4 / 5 ALA A 203
GLY A 196
CYH A 200
HIS A 242
 None
None
ZN  A 303 (-2.3A)
None
 1.31A 2yldA-3d2sA:
undetectable		 2yldA-3d2sA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 3d2s MUSCLEBLIND-LIKE
PROTEIN 1
(Homo
sapiens) 		4 / 5 ALA A 203
GLY A 196
CYH A 200
HIS A 242
 None
None
ZN  A 303 (-2.3A)
None
 1.34A 2ylgA-3d2sA:
undetectable		 2ylgA-3d2sA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 3d2s MUSCLEBLIND-LIKE
PROTEIN 1
(Homo
sapiens) 		4 / 5 ALA A 203
GLY A 196
CYH A 200
HIS A 242
 None
None
ZN  A 303 (-2.3A)
None
 1.31A 3zwiA-3d2sA:
undetectable		 3zwiA-3d2sA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CIP_A_ASCA130_0
(CYTOCHROME C')		 3d2s MUSCLEBLIND-LIKE
PROTEIN 1
(Homo
sapiens) 		4 / 4 ALA A 203
GLY A 196
CYH A 200
HIS A 242
 None
None
ZN  A 303 (-2.3A)
None
 1.31A 4cipA-3d2sA:
undetectable		 4cipA-3d2sA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8J_A_ADNA401_1
(RNA 3'-TERMINAL
PHOSPHATE CYCLASE)		 3d2s MUSCLEBLIND-LIKE
PROTEIN 1
(Homo
sapiens) 		5 / 12 LEU A 182
PRO A 239
TYR A 224
GLN A 244
HIS A 242
 None
 1.25A 4o8jA-3d2sA:
0.0		 4o8jA-3d2sA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8J_B_ADNB401_1
(RNA 3'-TERMINAL
PHOSPHATE CYCLASE)		 3d2s MUSCLEBLIND-LIKE
PROTEIN 1
(Homo
sapiens) 		5 / 12 LEU A 182
PRO A 239
TYR A 224
GLN A 244
HIS A 242
 None
 1.25A 4o8jB-3d2sA:
0.0		 4o8jB-3d2sA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 3d2s MUSCLEBLIND-LIKE
PROTEIN 1
(Homo
sapiens) 		4 / 5 ALA A 203
GLY A 196
CYH A 200
HIS A 242
 None
None
ZN  A 303 (-2.3A)
None
 1.29A 5jliA-3d2sA:
undetectable		 5jliA-3d2sA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSL_A_ASCA202_0
(CYTOCHROME C')		 3d2s MUSCLEBLIND-LIKE
PROTEIN 1
(Homo
sapiens) 		4 / 4 ALA A 203
GLY A 196
CYH A 200
HIS A 242
 None
None
ZN  A 303 (-2.3A)
None
 1.31A 5jslA-3d2sA:
undetectable		 5jslA-3d2sA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 3d2s MUSCLEBLIND-LIKE
PROTEIN 1
(Homo
sapiens) 		4 / 5 ALA A 203
GLY A 196
CYH A 200
HIS A 242
 None
None
ZN  A 303 (-2.3A)
None
 1.32A 5jt4A-3d2sA:
undetectable		 5jt4A-3d2sA:
17.59