SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d2u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3d2u UL18 PROTEIN
(Human
betaherpesvirus
5) 		5 / 12 TYR A  62
GLY A  47
SER A  56
TRP A  51
GLY A  23
 None
 0.87A 1kiaA-3d2uA:
undetectable		 1kiaA-3d2uA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3d2u UL18 PROTEIN
(Human
betaherpesvirus
5) 		5 / 12 TYR A  62
GLY A  47
SER A  56
TRP A  51
GLY A  23
 None
 0.85A 1nbhB-3d2uA:
undetectable		 1nbhB-3d2uA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3d2u UL18 PROTEIN
(Human
betaherpesvirus
5) 		5 / 12 TYR A  62
GLY A  47
SER A  56
TRP A  51
GLY A  23
 None
 0.88A 1nbiA-3d2uA:
undetectable		 1nbiA-3d2uA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3d2u UL18 PROTEIN
(Human
betaherpesvirus
5) 		5 / 12 TYR A  62
GLY A  47
SER A  56
TRP A  51
GLY A  23
 None
 0.88A 1nbiB-3d2uA:
undetectable		 1nbiB-3d2uA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3d2u UL18 PROTEIN
(Human
betaherpesvirus
5) 		5 / 12 TYR A  62
GLY A  47
SER A  56
TRP A  51
GLY A  23
 None
 1.07A 1nbiC-3d2uA:
undetectable		 1nbiC-3d2uA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3d2u UL18 PROTEIN
(Human
betaherpesvirus
5) 		5 / 12 TYR A  62
GLY A  47
SER A  56
TRP A  51
GLY A  23
 None
 1.07A 1nbiD-3d2uA:
undetectable		 1nbiD-3d2uA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 3d2u UL18 PROTEIN
(Human
betaherpesvirus
5) 		3 / 3 TRP A 177
GLU A  66
TYR A  62
 None
 0.96A 2a3aA-3d2uA:
undetectable		 2a3aA-3d2uA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 3d2u UL18 PROTEIN
(Human
betaherpesvirus
5) 		3 / 3 LEU A   3
TYR A 181
GLY A 183
 None
 0.57A 2ocuA-3d2uA:
undetectable		 2ocuA-3d2uA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3d2u UL18 PROTEIN
(Human
betaherpesvirus
5) 		3 / 3 PRO A 240
LEU A 241
GLN A 251
 None
 0.60A 3hznG-3d2uA:
undetectable
3hznH-3d2uA:
undetectable		 3hznG-3d2uA:
17.87
3hznH-3d2uA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 3d2u UL18 PROTEIN
(Human
betaherpesvirus
5) 		4 / 6 PHE A  31
HIS A  34
THR A  32
VAL A  21
 None
 1.29A 3lb3A-3d2uA:
undetectable		 3lb3A-3d2uA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3d2u UL18 PROTEIN
(Human
betaherpesvirus
5) 		4 / 8 PRO A 191
SER A 211
VAL A 193
VAL A 188
 None
 0.98A 4mk4A-3d2uA:
undetectable		 4mk4A-3d2uA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3d2u UL18 PROTEIN
(Human
betaherpesvirus
5) 		4 / 6 GLY A  70
ASP A  71
SER A  43
ARG A  67
 None
 1.22A 6dwdA-3d2uA:
undetectable
6dwdC-3d2uA:
undetectable		 6dwdA-3d2uA:
17.34
6dwdC-3d2uA:
17.34