SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d37'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 3d37 TAIL PROTEIN, 43 KDA
(Neisseria
meningitidis) 		3 / 3 ARG A  92
THR A 150
VAL A  99
 None
CL  A 383 ( 4.1A)
CL  A 383 ( 4.0A)
 0.70A 1hxbA-3d37A:
undetectable		 1hxbA-3d37A:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 3d37 TAIL PROTEIN, 43 KDA
(Neisseria
meningitidis) 		5 / 8 ASP A 327
GLU A 201
GLY A 285
ASP A 204
THR A 281
 None
 1.31A 1m4iA-3d37A:
undetectable		 1m4iA-3d37A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZEA_A_DHIA6_0
(MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
H CHAIN
MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
L CHAIN
SHORT SYNTHETIC
D-AMINO ACID PEPTIDE
D2)		 3d37 TAIL PROTEIN, 43 KDA
(Neisseria
meningitidis) 		3 / 3 TRP A 295
ARG A 319
PHE A 321
 None
 1.02A 1zeaH-3d37A:
undetectable
1zeaL-3d37A:
undetectable		 1zeaH-3d37A:
18.02
1zeaL-3d37A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_1
(POL PROTEIN)		 3d37 TAIL PROTEIN, 43 KDA
(Neisseria
meningitidis) 		5 / 11 ILE A 340
ALA A 312
ASP A 311
ILE A 282
PHE A 278
 None
 1.00A 2fxdA-3d37A:
undetectable		 2fxdA-3d37A:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)		 3d37 TAIL PROTEIN, 43 KDA
(Neisseria
meningitidis) 		3 / 3 ARG A  92
THR A 150
VAL A  99
 None
CL  A 383 ( 4.1A)
CL  A 383 ( 4.0A)
 0.70A 2q64A-3d37A:
undetectable		 2q64A-3d37A:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3d37 TAIL PROTEIN, 43 KDA
(Neisseria
meningitidis) 		3 / 3 ARG A  92
THR A 150
VAL A  99
 None
CL  A 383 ( 4.1A)
CL  A 383 ( 4.0A)
 0.65A 2qakA-3d37A:
undetectable		 2qakA-3d37A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 3d37 TAIL PROTEIN, 43 KDA
(Neisseria
meningitidis) 		5 / 9 LEU A  87
ILE A  42
GLY A  43
LEU A  89
SER A  90
 None
 1.09A 3ai9X-3d37A:
undetectable		 3ai9X-3d37A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 3d37 TAIL PROTEIN, 43 KDA
(Neisseria
meningitidis) 		5 / 10 ALA A 116
LEU A 155
VAL A 176
ILE A 127
LEU A 168
 None
 1.17A 3jw3A-3d37A:
undetectable		 3jw3A-3d37A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_A_NCAA192_0
(NICOTINAMIDASE)		 3d37 TAIL PROTEIN, 43 KDA
(Neisseria
meningitidis) 		5 / 11 ASP A  53
LEU A  87
LEU A  54
ILE A  73
SER A  55
 None
 1.26A 3o94A-3d37A:
undetectable		 3o94A-3d37A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_B_NCAB192_0
(NICOTINAMIDASE)		 3d37 TAIL PROTEIN, 43 KDA
(Neisseria
meningitidis) 		5 / 11 ASP A  53
LEU A  87
LEU A  54
ILE A  73
SER A  55
 None
 1.28A 3o94B-3d37A:
undetectable		 3o94B-3d37A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_C_NCAC192_0
(NICOTINAMIDASE)		 3d37 TAIL PROTEIN, 43 KDA
(Neisseria
meningitidis) 		5 / 11 ASP A  53
LEU A  87
LEU A  54
ILE A  73
SER A  55
 None
 1.29A 3o94C-3d37A:
undetectable		 3o94C-3d37A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_D_NCAD192_0
(NICOTINAMIDASE)		 3d37 TAIL PROTEIN, 43 KDA
(Neisseria
meningitidis) 		5 / 11 ASP A  53
LEU A  87
LEU A  54
ILE A  73
SER A  55
 None
 1.28A 3o94D-3d37A:
undetectable		 3o94D-3d37A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 3d37 TAIL PROTEIN, 43 KDA
(Neisseria
meningitidis) 		4 / 5 THR A 342
GLY A 177
VAL A 175
PRO A 166
 None
 1.03A 4grkA-3d37A:
undetectable		 4grkA-3d37A:
23.35