SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d3a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA153_1
(CALMODULIN)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 8 ILE A 174
LEU A 166
GLU A 107
ALA A 105
VAL A 112
 None
 1.13A 1a29A-3d3aA:
undetectable		 1a29A-3d3aA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CTR_A_TFPA153_1
(CALMODULIN)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 9 ILE A 174
LEU A 166
GLU A 107
ALA A 105
VAL A 112
 None
 1.11A 1ctrA-3d3aA:
undetectable		 1ctrA-3d3aA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 LEU A 461
THR A 409
GLY A 458
LEU A 455
 None
 0.84A 1gtiB-3d3aA:
undetectable		 1gtiB-3d3aA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 PRO A  55
GLY A 578
CYH A 579
PHE A 305
 None
 0.88A 1h4oB-3d3aA:
undetectable		 1h4oB-3d3aA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 PRO A  55
GLY A 578
CYH A 579
PHE A 305
 None
 0.85A 1h4oG-3d3aA:
undetectable		 1h4oG-3d3aA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 LEU A 433
VAL A 431
VAL A 498
VAL A 487
 None
 0.90A 1iwiA-3d3aA:
undetectable		 1iwiA-3d3aA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A  72
PHE A  28
VAL A  44
 None
 0.75A 1kijA-3d3aA:
undetectable		 1kijA-3d3aA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 PRO A  55
GLY A 578
CYH A 579
PHE A 305
 None
 0.85A 1oc3A-3d3aA:
undetectable		 1oc3A-3d3aA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A 125
ASN A  81
TRP A 308
 None
 0.87A 1r15D-3d3aA:
2.9		 1r15D-3d3aA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A 125
ASN A  81
TRP A 308
 None
 0.92A 1r15E-3d3aA:
3.0		 1r15E-3d3aA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A 125
ASN A  81
TRP A 308
 None
 0.90A 1r15F-3d3aA:
2.9		 1r15F-3d3aA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 327
LEU A  69
MET A 284
MET A  71
THR A 235
 None
 1.39A 2aa6A-3d3aA:
undetectable		 2aa6A-3d3aA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_B_STRB402_1
(MINERALOCORTICOID
RECEPTOR)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 327
LEU A  69
MET A 284
MET A  71
THR A 235
 None
 1.38A 2aa6B-3d3aA:
undetectable		 2aa6B-3d3aA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_B_017B203_1
(HIV-1 PROTEASE)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 GLU A 424
PRO A 318
ARG A 443
GLY A 446
 None
 1.31A 2hs1B-3d3aA:
undetectable		 2hs1B-3d3aA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 LEU A 433
VAL A 431
VAL A 498
VAL A 487
 None
 0.99A 2z97A-3d3aA:
undetectable		 2z97A-3d3aA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A 326
THR A 543
GLU A 331
 None
 0.83A 2zifB-3d3aA:
undetectable		 2zifB-3d3aA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA512_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 ALA A 270
TYR A 618
SER A 317
PHE A 265
HIS A 267
 None
 1.10A 2zm8A-3d3aA:
undetectable		 2zm8A-3d3aA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ILE A 588
MET A 547
THR A 573
LEU A 574
 None
 1.03A 3ag1N-3d3aA:
undetectable
3ag1W-3d3aA:
undetectable		 3ag1N-3d3aA:
20.83
3ag1W-3d3aA:
7.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 141
TRP A 131
TYR A 147
 None
 0.95A 3aicA-3d3aA:
3.1		 3aicA-3d3aA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 141
TRP A 131
TYR A 147
 None
 0.95A 3aicB-3d3aA:
4.3		 3aicB-3d3aA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 141
TRP A 131
TYR A 147
 None
 0.97A 3aicE-3d3aA:
3.3		 3aicE-3d3aA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 141
TRP A 131
TYR A 147
 None
 0.94A 3aicG-3d3aA:
3.4		 3aicG-3d3aA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 141
TRP A 131
TYR A 147
 None
 1.00A 3aicH-3d3aA:
4.0		 3aicH-3d3aA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A 235
SER A 276
LYS A 338
 None
 1.10A 3aocC-3d3aA:
undetectable		 3aocC-3d3aA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A 465
ILE A 405
LEU A 134
GLU A 396
ARG A 470
 None
 1.32A 3apwB-3d3aA:
undetectable		 3apwB-3d3aA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A 462
LEU A 464
GLN A 400
 None
 0.83A 3g4lA-3d3aA:
undetectable		 3g4lA-3d3aA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 GLY A 301
GLY A 263
CYH A  75
PHE A 101
 None
 0.93A 3ko0M-3d3aA:
undetectable
3ko0P-3d3aA:
undetectable		 3ko0M-3d3aA:
10.45
3ko0P-3d3aA:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 GLY A 301
GLY A 263
CYH A 121
PHE A  79
 None
 0.93A 3ko0M-3d3aA:
undetectable
3ko0P-3d3aA:
undetectable		 3ko0M-3d3aA:
10.45
3ko0P-3d3aA:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 LEU A 604
GLN A 572
THR A 573
GLU A 602
 None
 1.47A 3n58C-3d3aA:
3.8		 3n58C-3d3aA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 156
ARG A 142
ASN A  81
 None
 0.73A 3qxvD-3d3aA:
2.8		 3qxvD-3d3aA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA504_1
(CYTOCHROME P450 2B4)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 9 ILE A 113
ILE A 175
PHE A 294
GLU A  48
VAL A  44
 None
 1.41A 3tmzA-3d3aA:
undetectable		 3tmzA-3d3aA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 197
LEU A 210
VAL A 179
ASP A 198
 None
 0.95A 3ufnA-3d3aA:
undetectable
3ufnB-3d3aA:
undetectable		 3ufnA-3d3aA:
10.41
3ufnB-3d3aA:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 404
GLY A 403
GLN A 400
 None
 0.56A 3v4tH-3d3aA:
1.2		 3v4tH-3d3aA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 TYR A 323
TYR A 297
ARG A 275
LEU A 280
 None
 1.30A 3wipG-3d3aA:
undetectable
3wipH-3d3aA:
undetectable		 3wipG-3d3aA:
16.20
3wipH-3d3aA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ARG A 275
LEU A 280
TYR A 323
TYR A 297
 None
 1.26A 3wipF-3d3aA:
undetectable
3wipJ-3d3aA:
undetectable		 3wipF-3d3aA:
16.20
3wipJ-3d3aA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A 232
GLU A 182
ARG A 115
 None
 1.00A 3wxoA-3d3aA:
undetectable		 3wxoA-3d3aA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 GLN A 572
ASN A 546
THR A 601
TRP A 550
 None
 1.38A 4d1yA-3d3aA:
2.8
4d1yB-3d3aA:
undetectable		 4d1yA-3d3aA:
15.61
4d1yB-3d3aA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A  76
PRO A  52
ALA A 122
MET A 298
GLY A 301
 None
 1.38A 4j7xA-3d3aA:
undetectable		 4j7xA-3d3aA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ASN A 232
GLU A 259
GLU A  48
TYR A 111
 None
 1.22A 4mj8A-3d3aA:
undetectable
4mj8C-3d3aA:
undetectable		 4mj8A-3d3aA:
14.90
4mj8C-3d3aA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 216
ALA A 185
GLY A 184
GLY A 474
PHE A 473
 None
 1.18A 4obwA-3d3aA:
undetectable		 4obwA-3d3aA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_B_SAMB601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 216
ALA A 185
GLY A 184
GLY A 474
PHE A 473
 None
 1.03A 4obwB-3d3aA:
undetectable		 4obwB-3d3aA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 452
ASN A 434
LEU A 433
ARG A 460
LEU A 461
 None
 1.17A 4wg0I-3d3aA:
undetectable
4wg0J-3d3aA:
undetectable
4wg0K-3d3aA:
undetectable		 4wg0I-3d3aA:
2.49
4wg0J-3d3aA:
2.49
4wg0K-3d3aA:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP4_A_COCA706_1
(DOPAMINE TRANSPORTER)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 PHE A 260
ALA A 277
GLY A 283
SER A 262
GLY A 234
 None
 1.00A 4xp4A-3d3aA:
undetectable		 4xp4A-3d3aA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 TYR A  77
GLY A 117
GLU A 180
ASN A 181
 None
 1.21A 4zbqA-3d3aA:
undetectable		 4zbqA-3d3aA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 PHE A 512
HIS A 385
LEU A 383
PRO A 507
 None
 1.37A 5csyB-3d3aA:
9.7		 5csyB-3d3aA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSM_A_GCSA801_1
(EXO-BETA-D-GLUCOSAMI
NIDASE)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 12 TYR A  77
CYH A 121
GLU A 123
GLU A 182
GLU A 259
TYR A 297
 None
 1.01A 5gsmA-3d3aA:
35.8		 5gsmA-3d3aA:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSM_B_GCSB801_1
(EXO-BETA-D-GLUCOSAMI
NIDASE)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 12 TYR A  77
CYH A 121
GLU A 123
GLU A 182
GLU A 259
TYR A 297
 None
 0.99A 5gsmB-3d3aA:
15.2		 5gsmB-3d3aA:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_I_EY4I500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 GLN A 430
VAL A 431
PRO A 528
THR A 409
 None
 1.38A 6cduI-3d3aA:
undetectable
6cduJ-3d3aA:
undetectable		 6cduI-3d3aA:
18.63
6cduJ-3d3aA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 482
GLU A 466
VAL A 465
LEU A 464
ILE A 463
 None
 0.98A 6ectA-3d3aA:
undetectable		 6ectA-3d3aA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FI4_B_DVAB8_0
(14-3-3 PROTEIN SIGMA
PRO-SEP-LEU-PRO-DVA)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 SER A 293
VAL A  44
ASN A  72
PRO A  41
 None
 1.50A 6fi4A-3d3aA:
undetectable
6fi4B-3d3aA:
undetectable		 6fi4A-3d3aA:
17.04
6fi4B-3d3aA:
0.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 3d3a BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 469
HIS A 307
PRO A 607
VAL A 508
GLU A 466
 None
 1.24A 6gngA-3d3aA:
undetectable		 6gngA-3d3aA:
21.92