SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d3b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 3d3b 30S RIBOSOMAL
PROTEIN S10
(Escherichia
coli) 		4 / 6 ALA J  21
ILE J  25
LEU J  71
ALA J  12
 None
 0.82A 3r9sA-3d3bJ:
undetectable		 3r9sA-3d3bJ:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 3d3b 30S RIBOSOMAL
PROTEIN S10
(Escherichia
coli) 		4 / 6 ALA J  21
ILE J  25
LEU J  71
ALA J  12
 None
 0.82A 3r9sC-3d3bJ:
undetectable		 3r9sC-3d3bJ:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 3d3b 30S RIBOSOMAL
PROTEIN S10
(Escherichia
coli) 		5 / 12 LEU J  17
ALA J  21
GLU J  24
LEU J  71
LEU J  10
 None
 1.16A 4zn7A-3d3bJ:
undetectable		 4zn7A-3d3bJ:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 3d3b 30S RIBOSOMAL
PROTEIN S10
(Escherichia
coli) 		5 / 12 ILE J  25
LEU J  10
VAL J  26
ASP J  54
GLY J  38
 None
 1.23A 5nnaA-3d3bJ:
undetectable		 5nnaA-3d3bJ:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 3d3b 30S RIBOSOMAL
PROTEIN S10
(Escherichia
coli) 		5 / 12 ILE J  25
LEU J  10
VAL J  26
ASP J  54
GLY J  38
 None
 1.24A 5nnaB-3d3bJ:
undetectable		 5nnaB-3d3bJ:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 3d3b 30S RIBOSOMAL
PROTEIN S10
(Escherichia
coli) 		5 / 12 ILE J  25
LEU J  10
VAL J  26
ASP J  54
GLY J  38
 None
 1.21A 5nnaD-3d3bJ:
undetectable		 5nnaD-3d3bJ:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDM_A_ADNA904_1
(ATP-CITRATE SYNTHASE)		 3d3b 30S RIBOSOMAL
PROTEIN S10
(Escherichia
coli) 		4 / 4 THR J  62
ASP J  64
ARG J  68
LEU J  66
 None
 1.28A 5tdmA-3d3bJ:
undetectable		 5tdmA-3d3bJ:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3d3b 30S RIBOSOMAL
PROTEIN S10
(Escherichia
coli) 		3 / 3 ILE J  55
VAL J  36
PRO J  39
 None
 0.70A 5uunA-3d3bJ:
undetectable		 5uunA-3d3bJ:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3d3b 30S RIBOSOMAL
PROTEIN S10
(Escherichia
coli) 		3 / 3 HIS J  15
HIS J  49
ARG J  51
 None
 0.98A 6b58A-3d3bJ:
undetectable		 6b58A-3d3bJ:
9.57