SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d3j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 3d3j ENHANCER OF
MRNA-DECAPPING
PROTEIN 3
(Homo
sapiens) 		4 / 5 LEU A 368
GLY A 342
HIS A 344
ILE A 378
 None
 0.93A 1xf1A-3d3jA:
2.1		 1xf1A-3d3jA:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 3d3j ENHANCER OF
MRNA-DECAPPING
PROTEIN 3
(Homo
sapiens) 		4 / 4 GLY A 354
SER A 313
VAL A 362
LEU A 339
 None
 1.36A 1yajB-3d3jA:
undetectable		 1yajB-3d3jA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_B_017B203_1
(HIV-1 PROTEASE)		 3d3j ENHANCER OF
MRNA-DECAPPING
PROTEIN 3
(Homo
sapiens) 		4 / 7 GLU A 469
PRO A 445
LYS A 453
GLY A 472
 None
 1.24A 2hs1B-3d3jA:
undetectable		 2hs1B-3d3jA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)		 3d3j ENHANCER OF
MRNA-DECAPPING
PROTEIN 3
(Homo
sapiens) 		5 / 11 LEU A 406
LEU A 317
ALA A 316
ALA A 358
VAL A 362
 None
 1.29A 3e22D-3d3jA:
2.7		 3e22D-3d3jA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 3d3j ENHANCER OF
MRNA-DECAPPING
PROTEIN 3
(Homo
sapiens) 		5 / 12 GLY A 342
GLY A 347
ASN A 409
ASN A 416
LEU A 419
 None
 1.08A 3vywB-3d3jA:
5.0		 3vywB-3d3jA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3d3j ENHANCER OF
MRNA-DECAPPING
PROTEIN 3
(Homo
sapiens) 		4 / 8 LEU A 357
VAL A 364
LEU A 459
LEU A 440
 None
 0.97A 4l1xA-3d3jA:
undetectable		 4l1xA-3d3jA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BTX_A_EDTA503_0
(SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER))		 3d3j ENHANCER OF
MRNA-DECAPPING
PROTEIN 3
(Homo
sapiens) 		4 / 7 SER A 352
HIS A 356
GLY A 309
ARG A 355
 None
 1.12A 6btxA-3d3jA:
undetectable		 6btxA-3d3jA:
22.56