SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d3k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 3d3k ENHANCER OF
MRNA-DECAPPING
PROTEIN 3
(Homo
sapiens) 		4 / 5 HIS A 287
LEU A 299
SER A 495
GLY A 480
 None
 1.00A 1a4lB-3d3kA:
undetectable		 1a4lB-3d3kA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)		 3d3k ENHANCER OF
MRNA-DECAPPING
PROTEIN 3
(Homo
sapiens) 		4 / 6 LEU A 411
LEU A 339
LEU A 399
LEU A 305
 None
 0.88A 1errA-3d3kA:
undetectable		 1errA-3d3kA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 3d3k ENHANCER OF
MRNA-DECAPPING
PROTEIN 3
(Homo
sapiens) 		4 / 5 LEU A 368
GLY A 342
HIS A 344
ILE A 378
 None
 0.88A 1xf1A-3d3kA:
undetectable		 1xf1A-3d3kA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)		 3d3k ENHANCER OF
MRNA-DECAPPING
PROTEIN 3
(Homo
sapiens) 		4 / 6 LEU A 368
GLY A 342
HIS A 344
ILE A 378
 None
 0.86A 1xf1B-3d3kA:
undetectable		 1xf1B-3d3kA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 3d3k ENHANCER OF
MRNA-DECAPPING
PROTEIN 3
(Homo
sapiens) 		5 / 12 GLY A 350
LYS A 346
ASP A 443
ILE A 442
GLY A 309
 None
 1.38A 3ps9A-3d3kA:
3.9		 3ps9A-3d3kA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3d3k ENHANCER OF
MRNA-DECAPPING
PROTEIN 3
(Homo
sapiens) 		4 / 5 PHE A 486
LEU A 476
ILE A 491
VAL A 263
 None
 0.88A 3wrkA-3d3kA:
undetectable		 3wrkA-3d3kA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3d3k ENHANCER OF
MRNA-DECAPPING
PROTEIN 3
(Homo
sapiens) 		4 / 5 PRO A 444
ASP A 443
ILE A 474
VAL A 502
 None
 1.02A 4hytA-3d3kA:
undetectable		 4hytA-3d3kA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3d3k ENHANCER OF
MRNA-DECAPPING
PROTEIN 3
(Homo
sapiens) 		4 / 8 LEU A 357
VAL A 364
LEU A 459
LEU A 440
 None
 1.02A 4l1xA-3d3kA:
undetectable		 4l1xA-3d3kA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3d3k ENHANCER OF
MRNA-DECAPPING
PROTEIN 3
(Homo
sapiens) 		4 / 7 PHE A 486
ILE A 491
GLY A 462
LEU A 505
 None
 0.95A 4zdzA-3d3kA:
undetectable		 4zdzA-3d3kA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BTX_A_EDTA503_0
(SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER))		 3d3k ENHANCER OF
MRNA-DECAPPING
PROTEIN 3
(Homo
sapiens) 		4 / 7 SER A 352
HIS A 356
GLY A 309
LEU A 384
 None
 0.72A 6btxA-3d3kA:
undetectable		 6btxA-3d3kA:
20.50