SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d3q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDS_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 3d3q TRNA
DELTA(2)-ISOPENTENYL
PYROPHOSPHATE
TRANSFERASE
(Staphylococcus
epidermidis) 		5 / 12 VAL A  11
LEU A 113
TYR A 196
PHE A  81
MET A 288
 None
 1.43A 1fdsA-3d3qA:
4.5		 1fdsA-3d3qA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4D_A_TOYA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 3d3q TRNA
DELTA(2)-ISOPENTENYL
PYROPHOSPHATE
TRANSFERASE
(Staphylococcus
epidermidis) 		5 / 10 PHE A  76
ALA A 246
ASP A  48
THR A  51
ASP A  68
 None
 1.48A 1m4dA-3d3qA:
undetectable		 1m4dA-3d3qA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_B_CIAB2003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3d3q TRNA
DELTA(2)-ISOPENTENYL
PYROPHOSPHATE
TRANSFERASE
(Staphylococcus
epidermidis) 		5 / 12 ILE A  12
VAL A  27
ALA A  28
PHE A  31
PHE A   8
 None
 1.09A 1uduB-3d3qA:
undetectable		 1uduB-3d3qA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 3d3q TRNA
DELTA(2)-ISOPENTENYL
PYROPHOSPHATE
TRANSFERASE
(Staphylococcus
epidermidis) 		4 / 4 GLY A 248
SER A 273
VAL A 266
LEU A 226
 None
 1.07A 1yajB-3d3qA:
undetectable		 1yajB-3d3qA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 3d3q TRNA
DELTA(2)-ISOPENTENYL
PYROPHOSPHATE
TRANSFERASE
(Staphylococcus
epidermidis) 		5 / 10 ILE A 100
ILE A 101
TYR A 196
ILE A  89
ILE A  92
 None
 0.93A 3p4wD-3d3qA:
undetectable		 3p4wD-3d3qA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 3d3q TRNA
DELTA(2)-ISOPENTENYL
PYROPHOSPHATE
TRANSFERASE
(Staphylococcus
epidermidis) 		5 / 10 ILE A 100
ILE A 101
TYR A 196
ILE A  89
ILE A  92
 None
 0.93A 3p4wE-3d3qA:
undetectable		 3p4wE-3d3qA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 3d3q TRNA
DELTA(2)-ISOPENTENYL
PYROPHOSPHATE
TRANSFERASE
(Staphylococcus
epidermidis) 		3 / 3 TRP A 283
GLN A 275
THR A 282
 None
 0.99A 4m2xA-3d3qA:
2.3		 4m2xA-3d3qA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 3d3q TRNA
DELTA(2)-ISOPENTENYL
PYROPHOSPHATE
TRANSFERASE
(Staphylococcus
epidermidis) 		5 / 12 LEU A 300
LEU A 199
ILE A 201
LYS A 295
ILE A  12
 None
 1.11A 4y0pA-3d3qA:
undetectable		 4y0pA-3d3qA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3d3q TRNA
DELTA(2)-ISOPENTENYL
PYROPHOSPHATE
TRANSFERASE
(Staphylococcus
epidermidis) 		5 / 10 THR A  16
SER A  18
GLY A  38
ALA A 102
SER A  24
 None
 1.39A 5l66K-3d3qA:
undetectable
5l66L-3d3qA:
undetectable		 5l66K-3d3qA:
18.34
5l66L-3d3qA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3d3q TRNA
DELTA(2)-ISOPENTENYL
PYROPHOSPHATE
TRANSFERASE
(Staphylococcus
epidermidis) 		5 / 10 THR A  16
SER A  18
GLY A  38
ALA A 102
SER A  24
 None
 1.39A 5l66Y-3d3qA:
undetectable
5l66Z-3d3qA:
undetectable		 5l66Y-3d3qA:
18.34
5l66Z-3d3qA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 3d3q TRNA
DELTA(2)-ISOPENTENYL
PYROPHOSPHATE
TRANSFERASE
(Staphylococcus
epidermidis) 		5 / 12 ASN A 228
GLN A 231
GLU A 229
LEU A 226
LEU A 252
 None
 1.24A 5nwwA-3d3qA:
undetectable		 5nwwA-3d3qA:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3d3q TRNA
DELTA(2)-ISOPENTENYL
PYROPHOSPHATE
TRANSFERASE
(Staphylococcus
epidermidis) 		4 / 5 LEU A 252
VAL A 230
GLU A 229
LEU A 226
 None
 0.98A 5xooB-3d3qA:
undetectable		 5xooB-3d3qA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 3d3q TRNA
DELTA(2)-ISOPENTENYL
PYROPHOSPHATE
TRANSFERASE
(Staphylococcus
epidermidis) 		4 / 6 PRO A  63
ILE A  25
GLY A  61
GLU A  60
 None
 1.14A 6gqiA-3d3qA:
undetectable		 6gqiA-3d3qA:
19.46