SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d3y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 3d3y UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 5 LEU A 136
LEU A 140
LEU A 153
GLY A 172
 None
 1.06A 1a4lC-3d3yA:
undetectable		 1a4lC-3d3yA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_A_ESTA351_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3d3y UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 VAL A 206
LEU A 211
GLY A 204
LEU A 110
VAL A 107
 None
 1.12A 1fduA-3d3yA:
undetectable		 1fduA-3d3yA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)		 3d3y UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 7 PHE A 279
GLY A 277
THR A 350
ILE A 392
 None
 1.11A 2bdmA-3d3yA:
undetectable		 2bdmA-3d3yA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_2
(PROTEASE)		 3d3y UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		3 / 3 ARG A 343
VAL A 274
THR A 350
 None
 0.83A 2nnkA-3d3yA:
undetectable		 2nnkA-3d3yA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 3d3y UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		3 / 3 ASP A 199
THR A 384
GLU A 372
 None
 0.83A 2zifB-3d3yA:
undetectable		 2zifB-3d3yA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZS9_A_PAUA603_0
(PANTOTHENATE KINASE)		 3d3y UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 6 VAL A 326
ASP A 319
LYS A 253
TYR A 300
 None
EDO  A 428 (-3.6A)
None
None
 1.42A 2zs9A-3d3yA:
undetectable		 2zs9A-3d3yA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_1
(PROTEASE)		 3d3y UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 8 ARG A 246
ALA A 151
GLY A 317
ILE A 318
 None
 0.72A 3el9A-3d3yA:
undetectable		 3el9A-3d3yA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_2
(HIV-1 PROTEASE)		 3d3y UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		3 / 3 ARG A 343
VAL A 274
THR A 350
 None
 0.86A 3k4vA-3d3yA:
undetectable		 3k4vA-3d3yA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_3
(PROTEASE)		 3d3y UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		3 / 3 ARG A 343
VAL A 274
THR A 350
 None
 0.83A 3nduD-3d3yA:
undetectable		 3nduD-3d3yA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_2
(PROTEASE)		 3d3y UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		3 / 3 ARG A 343
VAL A 274
THR A 350
 None
 0.82A 3pwrA-3d3yA:
undetectable		 3pwrA-3d3yA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_2
(HIV-1 PROTEASE)		 3d3y UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 7 ARG A 246
ALA A 151
GLY A 317
ILE A 318
 None
 0.79A 3spkB-3d3yA:
undetectable		 3spkB-3d3yA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_2
(PROTEASE)		 3d3y UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		3 / 3 ARG A 343
VAL A 274
THR A 350
 None
 0.84A 3tl9A-3d3yA:
undetectable		 3tl9A-3d3yA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_A_MTXA603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3d3y UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 VAL A 314
LEU A 327
SER A 331
ILE A 240
THR A 316
 None
 0.90A 4ky8A-3d3yA:
undetectable		 4ky8A-3d3yA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_B_MTXB603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3d3y UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 VAL A 314
LEU A 327
SER A 331
ILE A 240
THR A 316
 None
 1.00A 4ky8B-3d3yA:
undetectable		 4ky8B-3d3yA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_C_MTXC603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3d3y UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 VAL A 314
LEU A 327
SER A 331
ILE A 240
THR A 316
 None
 0.95A 4ky8C-3d3yA:
undetectable		 4ky8C-3d3yA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_D_MTXD603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3d3y UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 VAL A 314
LEU A 327
SER A 331
ILE A 240
THR A 316
 None
 0.94A 4ky8D-3d3yA:
undetectable		 4ky8D-3d3yA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_E_MTXE603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3d3y UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 VAL A 314
LEU A 327
SER A 331
ILE A 240
THR A 316
 None
 0.97A 4ky8E-3d3yA:
undetectable		 4ky8E-3d3yA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)		 3d3y UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 6 ASP A 363
ASN A 364
ALA A 361
TYR A 358
 None
 1.18A 4mdaA-3d3yA:
undetectable		 4mdaA-3d3yA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 3d3y UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 7 TYR A 258
ARG A 338
SER A 331
LEU A 334
 None
 1.10A 5bphB-3d3yA:
undetectable		 5bphB-3d3yA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 3d3y UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 6 TYR A 258
ARG A 338
SER A 331
LEU A 334
 None
 1.07A 5bphD-3d3yA:
undetectable		 5bphD-3d3yA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3d3y UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 10 LEU A 327
VAL A 314
VAL A 291
ALA A 301
LEU A 256
 None
 1.13A 6czmA-3d3yA:
undetectable
6czmC-3d3yA:
undetectable		 6czmA-3d3yA:
22.87
6czmC-3d3yA:
22.87