SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d45'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_A_FLPA1650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		5 / 12 VAL A 277
LEU A 315
ILE A 267
ALA A 271
SER A 273
 None
 0.89A 1cqeA-3d45A:
undetectable		 1cqeA-3d45A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_B_FLPB2650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		5 / 12 VAL A 277
LEU A 315
ILE A 267
ALA A 271
SER A 273
 None
 0.88A 1cqeB-3d45A:
undetectable		 1cqeB-3d45A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_A_IBPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		5 / 9 VAL A 277
LEU A 315
ILE A 267
ALA A 271
SER A 273
 None
 0.96A 1eqgA-3d45A:
undetectable		 1eqgA-3d45A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_A_FLPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		5 / 12 VAL A 277
LEU A 315
ILE A 267
ALA A 271
SER A 273
 None
 0.90A 1eqhA-3d45A:
undetectable		 1eqhA-3d45A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		5 / 12 VAL A 277
LEU A 315
ILE A 267
ALA A 271
SER A 273
 None
 0.91A 1eqhB-3d45A:
undetectable		 1eqhB-3d45A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 1.02A 1p7lC-3d45A:
undetectable		 1p7lC-3d45A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 1.01A 1p7lD-3d45A:
undetectable		 1p7lD-3d45A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 0.96A 1rg9A-3d45A:
undetectable		 1rg9A-3d45A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 0.95A 1rg9B-3d45A:
undetectable		 1rg9B-3d45A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 0.99A 1rg9C-3d45A:
undetectable		 1rg9C-3d45A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 0.99A 1rg9D-3d45A:
undetectable		 1rg9D-3d45A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 ASP A 259
GLY A 130
PHE A  93
TYR A 133
 None
 1.01A 2aouA-3d45A:
undetectable		 2aouA-3d45A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		5 / 12 VAL A 277
LEU A 315
ILE A 267
ALA A 271
SER A 273
 None
 0.95A 2aylB-3d45A:
undetectable		 2aylB-3d45A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 0.90A 2obvA-3d45A:
undetectable		 2obvA-3d45A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 5 LEU A 457
ALA A 487
ILE A 499
SER A 491
 None
 0.89A 2othA-3d45A:
undetectable		 2othA-3d45A:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 0.91A 2p02A-3d45A:
undetectable		 2p02A-3d45A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLK_B_SPMB1302_1
(ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 10)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 4 ALA A 376
TYR A 377
ALA A 372
TYR A 374
 None
 1.20A 2wlkA-3d45A:
undetectable
2wlkB-3d45A:
undetectable		 2wlkA-3d45A:
20.12
2wlkB-3d45A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZTH_A_SAMA305_1
(CATECHOL
O-METHYLTRANSFERASE)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		3 / 3 SER A 385
GLU A 345
ASP A 349
 None
 0.83A 2zthA-3d45A:
undetectable		 2zthA-3d45A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		3 / 3 SER A 385
GLU A 345
ASP A 349
 None
 0.85A 3bwmA-3d45A:
undetectable		 3bwmA-3d45A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		5 / 12 VAL A 277
LEU A 315
ILE A 267
ALA A 271
SER A 273
 None
 0.91A 3kk6A-3d45A:
undetectable		 3kk6A-3d45A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 PHE A  69
PHE A  90
PHE A 263
ALA A 269
 None
 0.87A 3t3sD-3d45A:
undetectable		 3t3sD-3d45A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 5 PHE A 411
PHE A 327
ALA A 322
LEU A 316
 None
 1.12A 3t3zC-3d45A:
undetectable		 3t3zC-3d45A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		5 / 9 ASP A 285
GLY A  29
ASP A 375
ILE A  34
LEU A 283
 None
None
None
GDP  A 652 ( 4.4A)
GDP  A 652 ( 4.2A)
 1.03A 3u7sB-3d45A:
undetectable		 3u7sB-3d45A:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 0.95A 4k0bB-3d45A:
undetectable		 4k0bB-3d45A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 0.98A 4kttA-3d45A:
undetectable		 4kttA-3d45A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 0.98A 4kttC-3d45A:
undetectable		 4kttC-3d45A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 0.97A 4l7iB-3d45A:
undetectable		 4l7iB-3d45A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 MET A 321
ALA A 322
VAL A 353
PHE A  74
 None
 0.93A 4ltwA-3d45A:
undetectable		 4ltwA-3d45A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 0.89A 4ndnA-3d45A:
undetectable		 4ndnA-3d45A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 7 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 0.93A 4ndnC-3d45A:
undetectable		 4ndnC-3d45A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 7 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 1.00A 4odjA-3d45A:
undetectable		 4odjA-3d45A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_2
(ESTROGEN RECEPTOR)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 6 LEU A 478
ASP A 438
ILE A 466
PRO A 435
 None
 1.08A 4xi3C-3d45A:
undetectable		 4xi3C-3d45A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		3 / 3 SER A 385
GLU A 345
ASP A 349
 None
 0.85A 4xudA-3d45A:
undetectable		 4xudA-3d45A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		3 / 3 GLU A   2
LYS A 125
ASN A  89
 None
 0.88A 4y1dA-3d45A:
undetectable
4y1dD-3d45A:
undetectable		 4y1dA-3d45A:
17.19
4y1dD-3d45A:
3.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 0.92A 5a1iA-3d45A:
undetectable		 5a1iA-3d45A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 7 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 0.92A 5a1iA-3d45A:
undetectable		 5a1iA-3d45A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 7 ILE A  34
GLY A  33
PHE A 293
PHE A  69
 GDP  A 652 ( 4.4A)
None
None
None
 1.14A 5hieA-3d45A:
undetectable		 5hieA-3d45A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 1.01A 5t8sB-3d45A:
undetectable		 5t8sB-3d45A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 GLU A  20
PHE A  74
SER A 355
LEU A 381
 None
 1.08A 5y2tB-3d45A:
undetectable		 5y2tB-3d45A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 7 PHE A  88
LEU A  71
ALA A  18
GLN A  68
 None
 1.21A 6b89A-3d45A:
undetectable		 6b89A-3d45A:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 0.99A 6fbnB-3d45A:
undetectable		 6fbnB-3d45A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 0.93A 6fboA-3d45A:
undetectable		 6fboA-3d45A:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 0.92A 6fcbA-3d45A:
undetectable		 6fcbA-3d45A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 8 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 0.93A 6fcdA-3d45A:
undetectable		 6fcdA-3d45A:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 7 HIS A 439
PRO A 481
ASP A 438
LYS A 436
 None
 0.91A 6g6rA-3d45A:
undetectable		 6g6rA-3d45A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3d45 POLY(A)-SPECIFIC
RIBONUCLEASE PARN
(Mus
musculus) 		4 / 6 LEU A 116
VAL A 278
PHE A  67
GLY A  33
 None
 1.03A 6hd4B-3d45A:
undetectable		 6hd4B-3d45A:
10.21