SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d4m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 3d4m GLUTAREDOXIN-2,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		5 / 12 SER A  70
TYR A  79
ALA A  22
GLY A  59
LEU A  53
 None
 1.18A 4j7xB-3d4mA:
undetectable		 4j7xB-3d4mA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA610_0
(SERUM ALBUMIN)		 3d4m GLUTAREDOXIN-2,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		3 / 3 VAL A   2
SER A   3
THR A   6
 None
 0.40A 4luhA-3d4mA:
undetectable		 4luhA-3d4mA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3d4m GLUTAREDOXIN-2,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		3 / 3 ILE A  85
VAL A  78
PRO A  76
 None
 0.69A 5uunA-3d4mA:
6.0		 5uunA-3d4mA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_1
(CYTOCHROME P450 1A1)		 3d4m GLUTAREDOXIN-2,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		4 / 5 ILE A  69
SER A  70
ALA A  22
LEU A  13
 None
 0.95A 6dwnA-3d4mA:
undetectable		 6dwnA-3d4mA:
16.36