SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d4r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CP3_B_RBTB1129_1 (B-CELL LYMPHOMA 6 PROTEIN)	3d4r	DOMAIN OF UNKNOWN FUNCTION FROM THE PFAM-B_34464 FAMILY (Methanococcus maripaludis)	4 / 7	ASN A 123 ARG A 108 LEU A 109 TYR A 107	None	0.85A	4cp3A-3d4rA: undetectable 4cp3B-3d4rA: undetectable	4cp3A-3d4rA: 18.39 4cp3B-3d4rA: 18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OLM_A_198A1001_2 (ANDROGEN RECEPTOR)	3d4r	DOMAIN OF UNKNOWN FUNCTION FROM THE PFAM-B_34464 FAMILY (Methanococcus maripaludis)	4 / 6	MET A 55 ILE A 20 ILE A 27 VAL A 18	None	0.99A	4olmA-3d4rA: undetectable	4olmA-3d4rA: 18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R38_A_RBFA201_2 (BLUE-LIGHT-ACTIVATED HISTIDINE KINASE 2)	3d4r	DOMAIN OF UNKNOWN FUNCTION FROM THE PFAM-B_34464 FAMILY (Methanococcus maripaludis)	4 / 8	THR A 81 VAL A 18 LEU A 43 ILE A 20	None	0.81A	4r38A-3d4rA: undetectable	4r38A-3d4rA: 20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A93_B_8NUB3001_1 (5-HYDROXYTRYPTAMINE RECEPTOR 2A,SOLUBLE CYTOCHROME B562)	3d4r	DOMAIN OF UNKNOWN FUNCTION FROM THE PFAM-B_34464 FAMILY (Methanococcus maripaludis)	4 / 5	ASP A 50 ILE A 3 PHE A 99 TYR A 146	None	1.20A	6a93B-3d4rA: undetectable	6a93B-3d4rA: 16.49

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4CP3_B_RBTB1129_1","B-CELL LYMPHOMA 6 PROTEIN;B-CELL LYMPHOMA 6 PROTEIN","3d4r","DOMAIN OF UNKNOWN FUNCTION FROM THE PFAM-B_34464 FAMILY","Methanococcus maripaludis",4,"ASN A 123;ARG A 108;LEU A 109;TYR A 107","None","0.85A","4cp3A-3d4rA:undetectable;4cp3B-3d4rA:undetectable","4cp3A-3d4rA:18.39;4cp3B-3d4rA:18.39"],["4OLM_A_198A1001_2","ANDROGEN RECEPTOR","3d4r","DOMAIN OF UNKNOWN FUNCTION FROM THE PFAM-B_34464 FAMILY","Methanococcus maripaludis",4,"MET A  55;ILE A  20;ILE A  27;VAL A  18","None","0.99A","4olmA-3d4rA:undetectable","4olmA-3d4rA:18.85"],["4R38_A_RBFA201_2","BLUE-LIGHT-ACTIVATED HISTIDINE KINASE 2","3d4r","DOMAIN OF UNKNOWN FUNCTION FROM THE PFAM-B_34464 FAMILY","Methanococcus maripaludis",4,"THR A  81;VAL A  18;LEU A  43;ILE A  20","None","0.81A","4r38A-3d4rA:undetectable","4r38A-3d4rA:20.59"],["6A93_B_8NUB3001_1","5-HYDROXYTRYPTAMINE RECEPTOR 2A,SOLUBLE CYTOCHROME B562","3d4r","DOMAIN OF UNKNOWN FUNCTION FROM THE PFAM-B_34464 FAMILY","Methanococcus maripaludis",4,"ASP A  50;ILE A   3;PHE A  99;TYR A 146","None","1.20A","6a93B-3d4rA:undetectable","6a93B-3d4rA:16.49"]]