SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d5o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3d5o SERUM AMYLOID
P-COMPONENT
(Homo
sapiens) 		5 / 11 THR A  81
SER A  82
SER A  72
PHE A  37
VAL A  63
 None
 1.41A 1q23L-3d5oA:
undetectable		 1q23L-3d5oA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3d5o SERUM AMYLOID
P-COMPONENT
(Homo
sapiens) 		5 / 12 LEU A   4
ALA A  39
PHE A  11
PHE A 150
VAL A 196
 None
 1.13A 4ib4A-3d5oA:
undetectable		 4ib4A-3d5oA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3d5o SERUM AMYLOID
P-COMPONENT
(Homo
sapiens) 		5 / 12 LEU A 188
ALA A  39
PHE A  11
PHE A 150
VAL A 196
 None
 1.22A 4ib4A-3d5oA:
undetectable		 4ib4A-3d5oA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3d5o SERUM AMYLOID
P-COMPONENT
(Homo
sapiens) 		4 / 6 PHE A  50
MET A 159
ILE A 131
VAL A 125
 None
 1.37A 4mk4B-3d5oA:
undetectable		 4mk4B-3d5oA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3d5o SERUM AMYLOID
P-COMPONENT
(Homo
sapiens) 		4 / 4 LEU A 157
ARG A  38
ILE A 154
PHE A  37
 None
 1.18A 5kirB-3d5oA:
undetectable		 5kirB-3d5oA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 3d5o SERUM AMYLOID
P-COMPONENT
(Homo
sapiens) 		5 / 12 LEU A   4
ALA A  39
PHE A  11
PHE A 150
VAL A 196
 None
 1.07A 5tudA-3d5oA:
undetectable		 5tudA-3d5oA:
19.59