SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d5p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3d5p PUTATIVE GLUCAN
SYNTHESIS REGULATOR
OF SMI1/KNR4 FAMILY
(Bacteroides
fragilis) 		5 / 12 ILE A  58
GLU A  23
SER A 117
ALA A 115
LEU A 122
 None
 1.11A 2xkwB-3d5pA:
undetectable		 2xkwB-3d5pA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3d5p PUTATIVE GLUCAN
SYNTHESIS REGULATOR
OF SMI1/KNR4 FAMILY
(Bacteroides
fragilis) 		5 / 12 VAL A  22
ASN A  65
LEU A  91
ASN A  42
LEU A  38
 None
 0.89A 4kuoA-3d5pA:
undetectable		 4kuoA-3d5pA:
23.26