SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d6c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3d6c THERMONUCLEASE
(Staphylococcus
aureus) 		5 / 9 MET A  65
PHE A  61
GLY A  20
ALA A 109
LEU A 108
 None
 1.14A 1jb0A-3d6cA:
undetectable		 1jb0A-3d6cA:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3d6c THERMONUCLEASE
(Staphylococcus
aureus) 		4 / 8 MET A  65
PHE A  61
ALA A 109
LEU A 108
 None
 0.79A 2o01A-3d6cA:
undetectable		 2o01A-3d6cA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_A_PQNA847_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3d6c THERMONUCLEASE
(Staphylococcus
aureus) 		5 / 9 MET A  65
PHE A  61
GLY A  20
ALA A 109
LEU A 108
 None
 1.14A 3pcqA-3d6cA:
undetectable		 3pcqA-3d6cA:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 3d6c THERMONUCLEASE
(Staphylococcus
aureus) 		5 / 12 GLU A  57
SER A  59
GLY A  20
THR A  41
THR A  44
 None
None
None
CA  A 150 (-4.9A)
None
 1.38A 3r75A-3d6cA:
undetectable		 3r75A-3d6cA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 3d6c THERMONUCLEASE
(Staphylococcus
aureus) 		5 / 12 GLU A  57
SER A  59
GLY A  20
THR A  41
THR A  44
 None
None
None
CA  A 150 (-4.9A)
None
 1.37A 3r75B-3d6cA:
undetectable		 3r75B-3d6cA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 3d6c THERMONUCLEASE
(Staphylococcus
aureus) 		5 / 11 GLU A  57
SER A  59
GLY A  20
THR A  41
THR A  44
 None
None
None
CA  A 150 (-4.9A)
None
 1.36A 3r76A-3d6cA:
undetectable		 3r76A-3d6cA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3d6c THERMONUCLEASE
(Staphylococcus
aureus) 		4 / 7 MET A  65
PHE A  61
ALA A 109
LEU A 108
 None
 1.08A 4xk8A-3d6cA:
undetectable		 4xk8A-3d6cA:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3d6c THERMONUCLEASE
(Staphylococcus
aureus) 		4 / 5 GLU A  52
THR A  44
GLU A  57
LEU A 103
 None
 1.11A 5hm8A-3d6cA:
undetectable		 5hm8A-3d6cA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3d6c THERMONUCLEASE
(Staphylococcus
aureus) 		4 / 5 GLU A  52
THR A  44
GLU A  57
LEU A 103
 None
 1.11A 5hm8B-3d6cA:
undetectable		 5hm8B-3d6cA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3d6c THERMONUCLEASE
(Staphylococcus
aureus) 		4 / 5 GLU A  52
THR A  44
GLU A  57
LEU A 103
 None
 1.11A 5hm8C-3d6cA:
undetectable		 5hm8C-3d6cA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3d6c THERMONUCLEASE
(Staphylococcus
aureus) 		4 / 5 GLU A  52
THR A  44
GLU A  57
LEU A 103
 None
 1.11A 5hm8D-3d6cA:
undetectable		 5hm8D-3d6cA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3d6c THERMONUCLEASE
(Staphylococcus
aureus) 		4 / 5 GLU A  52
THR A  44
GLU A  57
LEU A 103
 None
 1.11A 5hm8E-3d6cA:
undetectable		 5hm8E-3d6cA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3d6c THERMONUCLEASE
(Staphylococcus
aureus) 		4 / 5 GLU A  52
THR A  44
GLU A  57
LEU A 103
 None
 1.11A 5hm8F-3d6cA:
undetectable		 5hm8F-3d6cA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3d6c THERMONUCLEASE
(Staphylococcus
aureus) 		4 / 5 GLU A  52
THR A  44
GLU A  57
LEU A 103
 None
 1.11A 5hm8H-3d6cA:
undetectable		 5hm8H-3d6cA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 3d6c THERMONUCLEASE
(Staphylococcus
aureus) 		4 / 7 VAL A  23
LEU A  25
ALA A  17
LEU A  36
 None
 0.68A 5jq7A-3d6cA:
undetectable		 5jq7A-3d6cA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 3d6c THERMONUCLEASE
(Staphylococcus
aureus) 		4 / 7 VAL A  23
LEU A  25
ALA A  17
LEU A 103
 None
 0.65A 5jq7A-3d6cA:
undetectable		 5jq7A-3d6cA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3d6c THERMONUCLEASE
(Staphylococcus
aureus) 		5 / 9 MET A  65
PHE A  61
GLY A  20
ALA A 109
LEU A 108
 None
 1.14A 5l8rA-3d6cA:
undetectable		 5l8rA-3d6cA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3d6c THERMONUCLEASE
(Staphylococcus
aureus) 		5 / 12 MET A  65
PHE A  61
ALA A 109
LEU A 108
ALA A  58
 None
 1.31A 5oy02-3d6cA:
undetectable		 5oy02-3d6cA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_B_PQNB1844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3d6c THERMONUCLEASE
(Staphylococcus
aureus) 		5 / 10 MET A  65
PHE A  61
ALA A 109
LEU A 108
ALA A  58
 None
 1.42A 5oy0b-3d6cA:
undetectable		 5oy0b-3d6cA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3d6c THERMONUCLEASE
(Staphylococcus
aureus) 		5 / 10 MET A  65
PHE A  61
GLY A  20
ALA A 109
LEU A 108
 None
 1.17A 5zjiA-3d6cA:
undetectable
5zjiJ-3d6cA:
undetectable		 5zjiA-3d6cA:
19.42
5zjiJ-3d6cA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3d6c THERMONUCLEASE
(Staphylococcus
aureus) 		4 / 6 MET A  65
ALA A 109
LEU A 108
ALA A  58
 None
 1.12A 6fosB-3d6cA:
undetectable		 6fosB-3d6cA:
20.86