SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d6i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 3d6i MONOTHIOL
GLUTAREDOXIN-3
(Saccharomyces
cerevisiae) 		4 / 8 GLY A 122
HIS A 120
ILE A 117
ALA A  55
 None
 0.93A 2x0pA-3d6iA:
undetectable		 2x0pA-3d6iA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 3d6i MONOTHIOL
GLUTAREDOXIN-3
(Saccharomyces
cerevisiae) 		3 / 3 SER A  67
ASP A  97
ASN A  42
 None
 1.03A 3lsfB-3d6iA:
undetectable
3lsfE-3d6iA:
undetectable		 3lsfB-3d6iA:
17.06
3lsfE-3d6iA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 3d6i MONOTHIOL
GLUTAREDOXIN-3
(Saccharomyces
cerevisiae) 		3 / 3 ASP A  97
ASN A  42
SER A  67
 None
 0.99A 3lsfB-3d6iA:
undetectable
3lsfE-3d6iA:
undetectable		 3lsfB-3d6iA:
17.06
3lsfE-3d6iA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 3d6i MONOTHIOL
GLUTAREDOXIN-3
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 117
LEU A 140
LEU A  94
PHE A  64
ILE A  60
 None
 1.06A 5j7wD-3d6iA:
undetectable		 5j7wD-3d6iA:
17.87