SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3d6r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S43_A_478A401_2 (PROTEASE)	3d6r	NON-STRUCTURAL PROTEIN 1 (Influenza A virus)	5 / 10	GLY B 184 ILE B 128 VAL B 157 ILE B 160 ILE B 192	None	1.01A	3s43B-3d6rB: undetectable	3s43B-3d6rB: 20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PST_A_FOLA201_1 (DIHYDROFOLATE REDUCTASE)	3d6r	NON-STRUCTURAL PROTEIN 1 (Influenza A virus)	3 / 3	ILE B 123 ASP B 153 ARG B 220	None	0.70A	4pstA-3d6rB: undetectable	4pstA-3d6rB: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5C0O_F_SAMF301_0 (TRNA (ADENINE(58)-N(1))-M ETHYLTRANSFERASE TRMI)	3d6r	NON-STRUCTURAL PROTEIN 1 (Influenza A virus)	5 / 12	GLY B 179 GLY B 183 GLY B 184 LEU B 185 LEU B 147	None	0.98A	5c0oF-3d6rB: undetectable	5c0oF-3d6rB: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E5K_B_017B201_1 (HIV-1 PROTEASE)	3d6r	NON-STRUCTURAL PROTEIN 1 (Influenza A virus)	5 / 12	GLY B 183 ILE B 128 VAL B 157 ILE B 160 ILE B 192	None	0.82A	5e5kA-3d6rB: undetectable	5e5kA-3d6rB: 20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5T8H_B_478B401_2 (PROTEASE)	3d6r	NON-STRUCTURAL PROTEIN 1 (Influenza A virus)	5 / 12	GLY B 183 ILE B 128 VAL B 157 ILE B 160 ILE B 192	None	0.79A	5t8hB-3d6rB: undetectable	5t8hB-3d6rB: 20.83

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3S43_A_478A401_2","PROTEASE;PROTEASE","3d6r","NON-STRUCTURAL PROTEIN 1","Influenza A virus",5,"GLY B 184;ILE B 128;VAL B 157;ILE B 160;ILE B 192","None","1.01A","3s43B-3d6rB:undetectable","3s43B-3d6rB:20.83"],["4PST_A_FOLA201_1","DIHYDROFOLATE REDUCTASE","3d6r","NON-STRUCTURAL PROTEIN 1","Influenza A virus",3,"ILE B 123;ASP B 153;ARG B 220","None","0.70A","4pstA-3d6rB:undetectable","4pstA-3d6rB:21.95"],["5C0O_F_SAMF301_0","TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE TRMI","3d6r","NON-STRUCTURAL PROTEIN 1","Influenza A virus",5,"GLY B 179;GLY B 183;GLY B 184;LEU B 185;LEU B 147","None","0.98A","5c0oF-3d6rB:undetectable","5c0oF-3d6rB:undetectable"],["5E5K_B_017B201_1","HIV-1 PROTEASE;HIV-1 PROTEASE","3d6r","NON-STRUCTURAL PROTEIN 1","Influenza A virus",5,"GLY B 183;ILE B 128;VAL B 157;ILE B 160;ILE B 192","None","0.82A","5e5kA-3d6rB:undetectable","5e5kA-3d6rB:20.83"],["5T8H_B_478B401_2","PROTEASE","3d6r","NON-STRUCTURAL PROTEIN 1","Influenza A virus",5,"GLY B 183;ILE B 128;VAL B 157;ILE B 160;ILE B 192","None","0.79A","5t8hB-3d6rB:undetectable","5t8hB-3d6rB:20.83"]]